MeSH term | MeSH ID | Detail |
---|---|---|
Retrognathia | D063173 | 1 associated lipids |
Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
Scorpion Stings | D065008 | 1 associated lipids |
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Ramachandran R et al. | Tacrolimus combined with corticosteroids versus Modified Ponticelli regimen in treatment of idiopathic membranous nephropathy: Randomized control trial. | 2016 | Nephrology (Carlton) | pmid:26205759 |
Hurabielle C et al. | Certolizumab pegol - A new therapeutic option for refractory disseminated pyoderma gangrenosum associated with Crohn's disease. | 2016 | J Dermatolog Treat | pmid:25909366 |
Muduma G et al. | Systematic Review and Meta-Analysis of Tacrolimus versus Ciclosporin as Primary Immunosuppression After Liver Transplant. | 2016 | PLoS ONE | pmid:27812112 |
Prókai à et al. | Calcineurin-inhibition Results in Upregulation of Local Renin and Subsequent Vascular Endothelial Growth Factor Production in Renal Collecting Ducts. | 2016 | Transplantation | pmid:26502369 |
Unver Dogan N et al. | Investigation of developmental toxicity and teratogenicity of cyclosporine A, tacrolimus and their combinations with prednisolone. | 2016 | Regul. Toxicol. Pharmacol. | pmid:26993750 |
Garcovich S et al. | First report of hereditary Christ-Siemens-Touraine syndrome and non-segmental vitiligo association in a young adult: contraindication for vitiligo treatment. | 2016 | J Eur Acad Dermatol Venereol | pmid:25339629 |
Ferjani H et al. | Combination of tacrolimus and mycophenolate mofetil induces oxidative stress and genotoxicity in spleen and bone marrow of Wistar rats. | 2016 | Mutat. Res. | pmid:27776691 |
Deng S et al. | Mechanism of tacrolimus-induced chronic renal fibrosis following transplantation is regulated by ox-LDL and its receptor, LOX-1. | 2016 | Mol Med Rep | pmid:27633115 |
Fathy M et al. | Impact of CYP3A5 and MDR-1 gene polymorphisms on the dose and level of tacrolimus among living-donor liver transplanted patients: single center experience. | 2016 | Biomarkers | pmid:26856709 |
Størset E et al. | Low-target tacrolimus in de novo standard risk renal transplant recipients: A single-centre experience. | 2016 | Nephrology (Carlton) | pmid:26854648 |
Novosel MK and Bistrup C | Discontinuation of steroids in ABO-incompatible renal transplantation. | 2016 | Transpl. Int. | pmid:26706618 |
Suh SW et al. | Risk Factors for the Adverse Events after Conversion from Twice-Daily to Once-Daily Tacrolimus in Stable Liver Transplantation Patients. | 2016 | J. Korean Med. Sci. | pmid:27709847 |
Yamamoto T et al. | Tacrolimus vs. anti-tumour necrosis factor agents for moderately to severely active ulcerative colitis: a retrospective observational study. | 2016 | Aliment. Pharmacol. Ther. | pmid:26762838 |
Witt LJ et al. | Benefit of adjunctive tacrolimus in connective tissue disease-interstitial lung disease. | 2016 | Pulm Pharmacol Ther | pmid:26762710 |
Dayal S et al. | Treatment of Childhood Vitiligo Using Tacrolimus Ointment with Narrowband Ultraviolet B Phototherapy. | 2016 | Pediatr Dermatol | pmid:27699846 |
Ueda Y et al. | Interstitial cystitis associated with primary Sjögren's syndrome successfully treated with a combination of tacrolimus and corticosteroid: A case report and literature review. | 2016 | Mod Rheumatol | pmid:24720552 |
Singh JA et al. | Treatments for Lupus Nephritis: A Systematic Review and Network Metaanalysis. | 2016 | J. Rheumatol. | pmid:27585688 |
Jones-Hughes T et al. | Immunosuppressive therapy for kidney transplantation in adults: a systematic review and economic model. | 2016 | Health Technol Assess | pmid:27578428 |
Saito S et al. | Role of Paternal Antigen-Specific Treg Cells in Successful Implantation. | 2016 | Am. J. Reprod. Immunol. | pmid:26706630 |
Georgiou GK et al. | Calcineurin inhibitors and male fertility after renal transplantation - a review. | 2016 | Andrologia | pmid:26341518 |
Herden U et al. | Early Initiation of Everolimus After Liver Transplantation: A Single-Center Experience. | 2016 | Ann. Transplant. | pmid:26842532 |
Thomas KS et al. | Clinical outcomes and response of patients applying topical therapy for pyoderma gangrenosum: A prospective cohort study. | 2016 | J. Am. Acad. Dermatol. | pmid:27502313 |
Yamaguchi Y et al. | Plasma cell cheilitis successfully treated with topical calcineurin inhibitors. | 2016 | Eur J Dermatol | pmid:27502182 |
Shuker N et al. | Pretransplant Tacrolimus Dose Requirements Predict Early Posttransplant Dose Requirements in Blood Group AB0-Incompatible Kidney Transplant Recipients. | 2016 | Ther Drug Monit | pmid:26630539 |
Turrión-Merino L et al. | A Case Series of 4 Patients With Peristomal Pyoderma Gangrenosum: Review of Risk Factors and Treatment Response. | 2016 | Actas Dermosifiliogr | pmid:26626501 |
Niioka T et al. | Influence of everolimus on the pharmacokinetics of tacrolimus in Japanese renal transplant patients. | 2016 | Int. J. Urol. | pmid:26990259 |
Ogura Y et al. | Early Conversion From Twice-Daily Tacrolimus to Prolonged-Release Tacrolimus in Liver Transplantation: A Single-Center Experience. | 2016 | Ann. Transplant. | pmid:27432248 |
Asavakarn S et al. | Systematic Pharmaceutical Educational Approach to Enhance Drug Adherence in Liver Transplant Recipients. | 2016 | Transplant. Proc. | pmid:27320587 |
Limsrichamrern S et al. | Correlation of Hematocrit and Tacrolimus Level in Liver Transplant Recipients. | 2016 | Transplant. Proc. | pmid:27320581 |
Kim JD et al. | Single-Center Experience of ABO-Incompatible Living-Donor Liver Transplantation With a New Simplified Intravenous Immunoglobulin Protocol: A Propensity Score-Matching Analysis. | 2016 | Transplant. Proc. | pmid:27320573 |
Federico S et al. | Sublingual administration improves systemic exposure of tacrolimus in kidney transplant recipients: comparison with oral administration. | 2016 | Eur. J. Clin. Invest. | pmid:27240092 |
Mo S et al. | Improvement of FK506 Production in the High-Yielding Strain Streptomyces sp. RM7011 by Engineering the Supply of Allylmalonyl-CoA Through a Combination of Genetic and Chemical Approach. | 2016 | J. Microbiol. Biotechnol. | pmid:26502733 |
Sobiak J et al. | Pharmacokinetics of mycophenolate sodium co-administered with tacrolimus in the first year after renal transplantation. | 2016 | Eur J Drug Metab Pharmacokinet | pmid:25663618 |
Sharma P et al. | Protein Phosphatase 1-α Regulates AS160 Ser588 and Thr642 Dephosphorylation in Skeletal Muscle. | 2016 | Diabetes | pmid:27246912 |
Prytuła A et al. | Factors associated with 1,25-dihydroxyvitamin D3 concentrations in liver transplant recipients: a prospective observational longitudinal study. | 2016 | Endocrine | pmid:26433738 |
Nitta D et al. | Successful Pregnancy and Delivery in a Heart Transplantation Recipient. | 2016 | Int Heart J | pmid:27150004 |
Jovanović M and Golušin Z | Nonsteroidal Topical Immunomodulators in Allergology and Dermatology. | 2016 | Biomed Res Int | pmid:27144167 |
Ban YH et al. | The biosynthetic pathway of FK506 and its engineering: from past achievements to future prospects. | 2016 | J. Ind. Microbiol. Biotechnol. | pmid:26342319 |
Romano C et al. | Management of Acute Severe Colitis in Children With Ulcerative Colitis in the Biologics Era. | 2016 | Pediatrics | pmid:27244779 |
Fujii S et al. | Prior activation of inositol 1,4,5-trisphosphate receptors suppresses the subsequent induction of long-term potentiation in hippocampal CA1 neurons. | 2016 | Learn. Mem. | pmid:27084928 |
Han SS et al. | Monitoring the Intracellular Tacrolimus Concentration in Kidney Transplant Recipients with Stable Graft Function. | 2016 | PLoS ONE | pmid:27082871 |
Bianic F et al. | Cost-effectiveness of everolimus plus reduced tacrolimus in de novo liver-recipients in the Italian setting. | 2016 | J Med Econ | pmid:27081739 |
Tannuri AC et al. | Prognostic factors for the evolution and reversibility of chronic rejection in pediatric liver transplantation. | 2016 | Clinics (Sao Paulo) | pmid:27166772 |
Mok CC et al. | Tacrolimus versus mycophenolate mofetil for induction therapy of lupus nephritis: a randomised controlled trial and long-term follow-up. | 2016 | Ann. Rheum. Dis. | pmid:25550339 |
Ikeda M et al. | Successful Second Allogeneic Stem Cell Transplantation From a Sibling Donor for Relapse of Myelodysplastic Syndrome in a Recipient of a Renal Transplant From His Mother: Case Report. | 2016 | Transplant. Proc. | pmid:27932152 |
Suarez Benjumea A et al. | Hepatitis C Virus in Kidney Transplant Recipients: A Problem on the Path to Eradication. | 2016 | Transplant. Proc. | pmid:27932111 |
Rodriguez Cubillo B et al. | Risk Factors of Recurrence of Diabetic Nephropathy in Renal Transplants. | 2016 | Transplant. Proc. | pmid:27932117 |
Krämer BK et al. | Efficacy and safety of tacrolimus compared with ciclosporin-A in renal transplantation: 7-year observational results. | 2016 | Transpl. Int. | pmid:26565071 |
Pallet N et al. | Long-Term Clinical Impact of Adaptation of Initial Tacrolimus Dosing to CYP3A5 Genotype. | 2016 | Am. J. Transplant. | pmid:26990694 |
Stockwell J et al. | Protein phosphatase role in adenosine A1 receptor-induced AMPA receptor trafficking and rat hippocampal neuronal damage in hypoxia/reperfusion injury. | 2016 | Neuropharmacology | pmid:26626486 |