| MeSH term | MeSH ID | Detail |
|---|---|---|
| Retrognathia | D063173 | 1 associated lipids |
| Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
| Scorpion Stings | D065008 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Alak AM et al. | An HPLC/MS/MS assay for tacrolimus in patient blood samples. Correlation with results of an ELISA assay. | 1997 | J Pharm Biomed Anal | pmid:9447546 |
| Singh N et al. | Predictors and outcome of early- versus late-onset major bacterial infections in liver transplant recipients receiving tacrolimus (FK506) as primary immunosuppression. | 1997 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9447904 |
| Taylor DO | The use of tacrolimus and mycophenolate mofetil after cardiac transplantation. | 1997 | Curr. Opin. Cardiol. | pmid:9192485 |
| Harihara Y and Makuuchi M | [Partial liver transplantation]. | 1997 | Nippon Naika Gakkai Zasshi | pmid:9340350 |
| Hayashi S et al. | Adenovirus-mediated gene transfer to the xenogeneic liver in liver xenotransplantation: the transduction of complement regulatory factor genes (DAF and HRF20). | 1997 | Transplant. Proc. | pmid:9193595 |
| Wallemacq PE et al. | IMx tacrolimus II vs IMx tacrolimus microparticle enzyme immunoassay evaluated in renal and hepatic transplant patients. | 1997 | Clin. Chem. | pmid:9342026 |
| Hohage H et al. | Effects of cyclosporin A and FK 506 on lipid metabolism and fibrinogen in kidney transplant recipients. | 1997 | Clin Transplant | pmid:9193847 |
| Gold BG et al. | A nonimmunosuppressant FKBP-12 ligand increases nerve regeneration. | 1997 | Exp. Neurol. | pmid:9344552 |
| Katari SR et al. | Clinical features of acute reversible tacrolimus (FK 506) nephrotoxicity in kidney transplant recipients. | 1997 | Clin Transplant | pmid:9193849 |
| Ciancio G et al. | Post-transplant lymphoproliferative disease in kidney transplant patients in the new immunosuppressive era. | 1997 | Clin Transplant | pmid:9193850 |
| Jindal RM | Post-transplant hyperlipidaemia. | 1997 | Postgrad Med J | pmid:9497947 |
| Koneru B et al. | Blood transfusions in liver recipients: a conundrum or a clear benefit in the cyclosporine/tacrolimus era? | 1997 | Transplantation | pmid:9197350 |
| Cameron AM et al. | FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain. | 1997 | J. Biol. Chem. | pmid:9346894 |
| Sugitani A et al. | En bloc pancreas and kidney transplantation in a patient with limited vascular access. | 1997 | Transplantation | pmid:9197366 |
| Hosoi R et al. | Isoform-specific up-regulation by ouabain of Na+,K+-ATPase in cultured rat astrocytes. | 1997 | J. Neurochem. | pmid:9349566 |
| Guerini D | Calcineurin: not just a simple protein phosphatase. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9199180 |
| Krüger M et al. | Inhibition of CREB- and cAMP response element-mediated gene transcription by the immunosuppressive drugs cyclosporin A and FK506 in T cells. | 1997 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:9349628 |
| Rouviere N et al. | Immunosuppressor binding to the immunophilin FKBP59 affects the local structural dynamics of a surface beta-strand: time-resolved fluorescence study. | 1997 | Biochemistry | pmid:9200682 |
| Prokisch H et al. | Impairment of calcineurin function in Neurospora crassa reveals its essential role in hyphal growth, morphology and maintenance of the apical Ca2+ gradient. | 1997 | Mol. Gen. Genet. | pmid:9349701 |
| de Paulis A et al. | Human synovial mast cells. II. Heterogeneity of the pharmacologic effects of antiinflammatory and immunosuppressive drugs. | 1997 | Arthritis Rheum. | pmid:9082935 |
| Wagner K et al. | New-onset diabetes mellitus in pediatric thoracic organ recipients receiving tacrolimus-based immunosuppression. | 1997 | J. Heart Lung Transplant. | pmid:9087870 |
| Yasutomi M et al. | Evaluation of tetrahydropyranyladriamycin as an immunosuppressant in concordant xenotransplantation. | 1997 | J. Heart Lung Transplant. | pmid:9087871 |
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| Morrissey PE et al. | Correlation of clinical outcomes after tacrolimus conversion for resistant kidney rejection or cyclosporine toxicity with pathologic staging by the Banff criteria. | 1997 | Transplantation | pmid:9089224 |
| Midtvedt K et al. | Successful pregnancies in a combined pancreas and renal allograft recipient and in a renal graft recipient on tacrolimus treatment. | 1997 | Nephrol. Dial. Transplant. | pmid:9430893 |
| Kiuchi T et al. | A hepatic graft tuberculosis transmitted from a living-related donor. | 1997 | Transplantation | pmid:9089234 |
| Paterson DL and Singh N | Interactions between tacrolimus and antimicrobial agents. | 1997 | Clin. Infect. Dis. | pmid:9431391 |
| Krämer BK and Schweda F | Differing proteinuria control with cyclosporin and tacrolimus. | 1997 | Lancet | pmid:9093272 |
| Openshaw H | Peripheral neuropathy after bone marrow transplantation. | 1997 | Biol. Blood Marrow Transplant. | pmid:9360782 |
| Maurer M et al. | Hair growth modulation by topical immunophilin ligands: induction of anagen, inhibition of massive catagen development, and relative protection from chemotherapy-induced alopecia. | 1997 | Am. J. Pathol. | pmid:9094998 |
| Rinaldi M et al. | FK506 effectiveness in reducing acute rejection after heart transplantation: a prospective randomized study. | 1997 | J. Heart Lung Transplant. | pmid:9361242 |
| Steiner JP et al. | Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A. | 1997 | Nat. Med. | pmid:9095176 |
| Nakai A et al. | The immunosuppressant drug FK506 ameliorates secondary mitochondrial dysfunction following transient focal cerebral ischemia in the rat. | 1997 | Neurobiol. Dis. | pmid:9361306 |
| Reyes J et al. | Graft-versus-host disease after liver and small bowel transplantation in a child. | 1997 | Clin Transplant | pmid:9361921 |
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| Neu AM et al. | Evaluation of neurotoxicity in pediatric renal transplant recipients treated with tacrolimus (FK506). | 1997 | Clin Transplant | pmid:9361932 |
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| Waer M | New immunosuppressive agents for organ transplantation. | 1997 | Acta Clin Belg | pmid:9351290 |
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| Karlsson H and Nässberger L | FK506 suppresses the mitogen-induced increase in lymphocyte adhesiveness to endothelial cells, but does not affect endothelial cell activation in response to inflammatory stimuli. | 1997 | Transplantation | pmid:9355847 |
| van Hooff JP | Pneumocystis carinii pneumonia after renal transplantation. | 1997 | Transplantation | pmid:9158038 |
| Ishida H et al. | Cataract development induced by repeated oral dosing with FK506 (tacrolimus) in adult rats. | 1997 | Toxicology | pmid:9355935 |
| Siddiqui MA et al. | Lymphomatoid papulosis and FK 506. | 1997 | Int. J. Dermatol. | pmid:9159004 |
| Wang JH and Kelly PT | Attenuation of paired-pulse facilitation associated with synaptic potentiation mediated by postsynaptic mechanisms. | 1997 | J. Neurophysiol. | pmid:9356420 |
| Okudaira H et al. | Control of allergic diseases by regulation of cytokine gene transcription. | 1997 | Arb Paul Ehrlich Inst Bundesamt Sera Impfstoffe Frankf A M | pmid:9383912 |
| Lee JW et al. | Tacrolimus (FK506): validation of a sensitive enzyme-linked immunosorbent assay kit for and application to a clinical pharmacokinetic study. | 1997 | Ther Drug Monit | pmid:9108651 |
| Thyagarajan GK et al. | FK506-induced fulminant leukoencephalopathy after single-lung transplantation. | 1997 | Ann. Thorac. Surg. | pmid:9386723 |
| Holt DW and Johnston A | Tacrolimus quality assessment. | 1997 | Ther Drug Monit | pmid:9108659 |
| Wang MS et al. | Comparative dose-dependence study of FK506 and cyclosporin A on the rate of axonal regeneration in the rat sciatic nerve. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9262378 |
| McElwee KJ et al. | Topical FK506: a potent immunotherapy for alopecia areata? Studies using the Dundee experimental bald rat model. | 1997 | Br. J. Dermatol. | pmid:9390322 |
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| Zhang Q et al. | A specific method for the measurement of tacrolimus in human whole blood by liquid chromatography/tandem mass spectrometry. | 1997 | Ther Drug Monit | pmid:9263391 |
| Huang J and Schreiber SL | A yeast genetic system for selecting small molecule inhibitors of protein-protein interactions in nanodroplets. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9391035 |
| Hikita N et al. | Use of topical FK506 in a corneal graft rejection model in Lewis rats. | 1997 | Invest. Ophthalmol. Vis. Sci. | pmid:9112986 |
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| Ahsan N et al. | Successful reversal of acute vascular rejection in a renal allograft with combined mycophenolate mofetil and tacrolimus as primary immunotherapy. | 1997 | Clin Transplant | pmid:9113443 |
| Sokal EM et al. | Early signs and risk factors for the increased incidence of Epstein-Barr virus-related posttransplant lymphoproliferative diseases in pediatric liver transplant recipients treated with tacrolimus. | 1997 | Transplantation | pmid:9392308 |
| Alessiani M et al. | [Flexibility of the surgical model of intestinal transplantation in swine]. | 1997 | Minerva Chir | pmid:9432575 |
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| Yagi M et al. | Effect of a glutamine-enriched diet on small bowel allograft during immunosuppressive therapy. | 1997 | Nutrition | pmid:9290090 |
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