MeSH term | MeSH ID | Detail |
---|---|---|
Retrognathia | D063173 | 1 associated lipids |
Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
Scorpion Stings | D065008 | 1 associated lipids |
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gammie JS et al. | Tacrolimus-based partial conditioning produces stable mixed lymphohematopoietic chimerism and tolerance for cardiac allografts. | 1998 | Circulation | pmid:9852899 |
Radermacher J et al. | Pronounced renal vasoconstriction and systemic hypertension in renal transplant patients treated with cyclosporin A versus FK 506. | 1998 | Transpl. Int. | pmid:9503547 |
Pou L et al. | Therapeutic drug monitoring of tacrolimus in liver transplantation, phase III FK506 multicenter Spanish Study Group: a two-year follow-up. | 1998 | Ther Drug Monit | pmid:9853973 |
Brunet M et al. | Multicenter comparison of first- and second-generation IMx tacrolimus microparticle enzyme immunoassays in liver and kidney transplantation. | 1998 | Ther Drug Monit | pmid:9853987 |
Lukyanenko V et al. | Termination of Ca2+ release during Ca2+ sparks in rat ventricular myocytes. | 1998 | J. Physiol. (Lond.) | pmid:9508828 |
Mentzer RM et al. | Tacrolimus as a rescue immunosuppressant after heart and lung transplantation. The U.S. Multicenter FK506 Study Group. | 1998 | Transplantation | pmid:9448154 |
Ernst A et al. | Lung abcess complicating Legionella micdadei pneumonia in an adult liver transplant recipient: case report and review. | 1998 | Transplantation | pmid:9448158 |
Cavaillé-Coll MW and Elashoff MR | Commentary on a comparison of tacrolimus and cyclosporine for immunosuppression after cadaveric renal transplantation. | 1998 | Transplantation | pmid:9448161 |
Alaiti S et al. | Tacrolimus (FK506) ointment for atopic dermatitis: a phase I study in adults and children. | 1998 | J. Am. Acad. Dermatol. | pmid:9448208 |
Millis JM et al. | Successful use of tacrolimus for initial rejection episodes after liver transplantation. | 1998 | Transplant. Proc. | pmid:9636569 |
Platz KP et al. | FK506 for primary and rescue therapy following liver transplantation. | 1998 | Transplant. Proc. | pmid:9636570 |
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Cai TH et al. | Improved immunosuppression with combination tacrolimus (FK506) and mycophenolic acid in orthotopic liver transplantation. | 1998 | Transplant. Proc. | pmid:9636572 |
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Barinaga M | Signaling path may lead to better heart-failure therapies. | 1998 | Science | pmid:9575084 |
Miyasaka N | [Recent findings on etiological mechanism of autoimmune diseases]. | 1998 | Nippon Naika Gakkai Zasshi | pmid:9577564 |
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Sugi-Ikai N et al. | Increased frequencies of interleukin-2- and interferon-gamma-producing T cells in patients with active Behçet's disease. | 1998 | Invest. Ophthalmol. Vis. Sci. | pmid:9579479 |
Burke GW et al. | Use of tacrolimus and mycophenolate mofetil for pancreas-kidney transplantation with or without OKT3 induction. | 1998 | Transplant. Proc. | pmid:9636627 |
Gruessner RW | Antibody induction therapy in pancreas transplantation. | 1998 | Transplant. Proc. | pmid:9636632 |
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Schneeberger H et al. | Tacrolimus as a primary immunosuppressive therapy in cadaveric renal transplantation: five years' experience at a single center. | 1998 | Transplant. Proc. | pmid:9636642 |
Pham H et al. | Occurrence of gammopathies and lymphoproliferative disorders in liver transplant recipients randomized to tacrolimus (FK506)- or cyclosporine-based immunosuppression. | 1998 | Liver Transpl Surg | pmid:9516567 |
Uchida J et al. | Renal endothelin in FK506-induced nephrotoxicity in spontaneously hypertensive rats. | 1998 | Jpn. J. Pharmacol. | pmid:9517403 |
Schuppe HC et al. | Topical tacrolimus for pyoderma gangrenosum. | 1998 | Lancet | pmid:9519983 |
Sequeira M et al. | New-onset Majocchi's granuloma in two kidney transplant recipients under tacrolimus treatment. | 1998 | J. Am. Acad. Dermatol. | pmid:9520033 |
Herzberg GZ et al. | The effects of HLA mismatching and immunosuppressive therapy on early rejection outcome in pediatric heart transplant recipients. | 1998 | J. Heart Lung Transplant. | pmid:9883760 |
Harrison S et al. | Stimulation of airway sensory nerves by cyclosporin A and FK506 in guinea-pig isolated bronchus. | 1998 | Br. J. Pharmacol. | pmid:9884067 |
Samsó M and Wagenknecht T | Contributions of electron microscopy and single-particle techniques to the determination of the ryanodine receptor three-dimensional structure. | 1998 | J. Struct. Biol. | pmid:9615436 |
Fisher RA et al. | A prospective randomized trial of mycophenolate mofetil with neoral or tacrolimus after orthotopic liver transplantation. | 1998 | Transplantation | pmid:9884248 |
Morris-Stiff G et al. | Conversion of renal transplant recipients from cyclosporin (neoral) to tacrolimus (prograf) for haemolytic uraemic syndrome. | 1998 | Transpl. Int. | pmid:9664954 |
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Idilman R et al. | Immunosuppressive drug-induced leukoencephalopathy in patients with liver transplant. | 1998 | Eur J Gastroenterol Hepatol | pmid:9619393 |
Kyo M et al. | Morphological findings in non-episode biopsies of kidney transplant allografts treated with FK506 or cyclosporine. | 1998 | Transpl. Int. | pmid:9664955 |
Kikuchi M et al. | Protective effects of FK506 against glutamate-induced neurotoxicity in retinal cell culture. | 1998 | Invest. Ophthalmol. Vis. Sci. | pmid:9620083 |
Hernández-Herrera G et al. | Tacrolimus rescue therapy for cyclosporine-induced nephrotoxicity. | 1998 | Transpl. Int. | pmid:9664956 |
Lampen A et al. | Catalytic activities, protein- and mRNA-expression of cytochrome P450 isoenzymes in intestinal cell lines. | 1998 | Xenobiotica | pmid:9622846 |
Margarit C et al. | Efficacy and safety of oral low-dose tacrolimus treatment in liver transplantation. | 1998 | Transpl. Int. | pmid:9664992 |
Matsui H et al. | [Physiological role of calcineurin in central nervous system]. | 1998 | Tanpakushitsu Kakusan Koso | pmid:9655961 |
Pou L et al. | Influence of posttransplant time on dose and concentration of tacrolimus in liver transplant patients. | 1998 | Transpl. Int. | pmid:9664994 |
Furutani M et al. | Biochemical and genetic characterization of an FK506-sensitive peptidyl prolyl cis-trans isomerase from a thermophilic archaeon, Methanococcus thermolithotrophicus. | 1998 | J. Bacteriol. | pmid:9440528 |
Sasaki K et al. | Effect of FK 506 and splenectomy on orthotopic small bowel xenotransplantation in the hamster-to-rat animal models. | 1998 | Transplant. Proc. | pmid:9838521 |
Takayama J et al. | Living related liver transplantation in patients with ABO incompatibility. | 1998 | Transplant. Proc. | pmid:9838537 |
Wu MS et al. | Cyclosporine, but not FK 506 and rapamycin, enhances cell proliferation in mouse medullary thick ascending cultured cells. | 1998 | Transplant. Proc. | pmid:9838561 |
Oyanagui Y | Immunosuppressants enhance superoxide radical/nitric oxide-dependent dexamethasone suppression of ischemic paw edema in mice. | 1998 | Eur. J. Pharmacol. | pmid:9600660 |
Kliem V and Brunkhorst R | Tacrolimus in kidney transplantation. A clinical review. | 1998 | Nephron | pmid:9609456 |
Shu KH et al. | A multicenter trial of FK506 as rescue therapy for renal transplant recipients in Taiwan. | 1998 | Transplant. Proc. | pmid:9838570 |
Jurcevic S et al. | A new enzyme-linked immunosorbent assay to measure anti-endothelial antibodies after cardiac transplantation demonstrates greater inhibition of antibody formation by tacrolimus compared with cyclosporine. | 1998 | Transplantation | pmid:9603168 |
Abu-Elmagd K et al. | Clinical intestinal transplantation: new perspectives and immunologic considerations. | 1998 | J. Am. Coll. Surg. | pmid:9583691 |
Lo CM et al. | Use of FK506 as primary or rescue therapy after liver transplantation in Hong Kong. | 1998 | Transplant. Proc. | pmid:9838571 |
Beatty PR et al. | Effect of cyclosporine and tacrolimus on the growth of Epstein-Barr virus-transformed B-cell lines. | 1998 | Transplantation | pmid:9603175 |
Zervos XA et al. | Comparison of tacrolimus with microemulsion cyclosporine as primary immunosuppression in hepatitis C patients after liver transplantation. | 1998 | Transplantation | pmid:9583863 |
Shapiro R et al. | Alopecia as a consequence of tacrolimus therapy. | 1998 | Transplantation | pmid:9603186 |
Muraki T et al. | Effects of cyclosporine and FK506 on in vitro high shear-induced platelet reactivity in rat and human non-anticoagulated blood. | 1998 | Transplantation | pmid:9583878 |
Sikorski R and Peters R | Droplet discovery. | 1998 | Science | pmid:9454334 |
Kadry Z et al. | Kaposi's sarcoma in liver transplant recipients on FK506. | 1998 | Transplantation | pmid:9583882 |
Neylan JF et al. | Assessment of the frequency and costs of posttransplantation hospitalizations in patients receiving tacrolimus versus cyclosporine. | 1998 | Am. J. Kidney Dis. | pmid:9820446 |
Patella V et al. | Endogenous superallergen protein Fv induces IL-4 secretion from human Fc epsilon RI+ cells through interaction with the VH3 region of IgE. | 1998 | J. Immunol. | pmid:9820545 |
Rossi FM and Blau HM | Recent advances in inducible gene expression systems. | 1998 | Curr. Opin. Biotechnol. | pmid:9821271 |
Tamura F et al. | FK506 promotes liver regeneration by suppressing natural killer cell activity. | 1998 | J. Gastroenterol. Hepatol. | pmid:9715421 |
Antoni FA et al. | Ca2+/calcineurin-inhibited adenylyl cyclase, highly abundant in forebrain regions, is important for learning and memory. | 1998 | J. Neurosci. | pmid:9822726 |
Fukuda K et al. | cFKBP/SMAP; a novel molecule involved in the regulation of smooth muscle differentiation. | 1998 | Development | pmid:9716519 |
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Jacobson P et al. | Tacrolimus: a new agent for the prevention of graft-versus-host disease in hematopoietic stem cell transplantation. | 1998 | Bone Marrow Transplant. | pmid:9720734 |
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Yoshida A et al. | Studies of repeated administration of FK-506 on myocardial metabolism in rats. | 1998 | J Toxicol Sci | pmid:9922943 |
Varghese Z et al. | Oxidizability of low-density lipoproteins from Neoral and tacrolimus-treated renal transplant patients. | 1998 | Transplant. Proc. | pmid:9723384 |
Wingard JR et al. | Relationship of tacrolimus (FK506) whole blood concentrations and efficacy and safety after HLA-identical sibling bone marrow transplantation. | 1998 | Biol. Blood Marrow Transplant. | pmid:9923414 |
Atillasoy E et al. | Cholesterol levels long-term after liver transplant. | 1998 | Transplant. Proc. | pmid:9723387 |
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Kohnle M et al. | Conversion to tacrolimus in cyclosporin A treated patients with gum hyperplasia. | 1998 | Transplant. Proc. | pmid:9723413 |
Alessiani M et al. | Effect of perioperative donor bone marrow infusion after small bowel transplantation in swine: preliminary results. | 1998 | Transplant. Proc. | pmid:9745496 |
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Isobe M et al. | Downregulation of endothelin expression in allograft coronary arteries after gene therapy targeting Cdk2 kinase. | 1998 | Transplant. Proc. | pmid:9636407 |
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Fujimura T et al. | Cellular surface molecular and cytokine gene expression in rat heart allografts under optimal doses of cyclosporine and FK 506. | 1998 | Transplant. Proc. | pmid:9636413 |
Hashimoto Y et al. | Effects of intestinal and hepatic metabolism on the bioavailability of tacrolimus in rats. | 1998 | Pharm. Res. | pmid:9794505 |
Yoshimura N et al. | Development of a macromolecular prodrug of FK 506: III: In vivo disposition of FK 506-dextran conjugate. | 1998 | Transplant. Proc. | pmid:9636415 |
Kobayashi M et al. | Effects of FK506 on experimental membranous glomerulonephritis induced by cationized bovine serum albumin in rats. | 1998 | Nephrol. Dial. Transplant. | pmid:9794552 |
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Chen H et al. | FK 506 and rapamycin in combination are not antagonistic but produce extended small bowel graft survival in the mouse. | 1998 | Transplant. Proc. | pmid:9636419 |
Faure JD et al. | An Arabidopsis immunophilin, AtFKBP12, binds to AtFIP37 (FKBP interacting protein) in an interaction that is disrupted by FK506. | 1998 | Plant J. | pmid:9807817 |
Busque S et al. | Conversion from Neoral (cyclosporine) to tacrolimus of kidney transplant recipients for gingival hyperplasia or hypertrichosis. | 1998 | Transplant. Proc. | pmid:9636507 |
Loss GE et al. | Reversal of delayed hyperacute renal allograft rejection with a tacrolimus-based therapeutic regimen. | 1998 | Transplant. Proc. | pmid:9636508 |
Kliem V et al. | Tacrolimus for steroid- and OKT3-resistant rejection in kidney recipients. | 1998 | Transplant. Proc. | pmid:9636509 |
Hodak SP et al. | QT prolongation and near fatal cardiac arrhythmia after intravenous tacrolimus administration: a case report. | 1998 | Transplantation | pmid:9734501 |
Copley JB et al. | Cyclosporine to tacrolimus: effect on hypertension and lipid profiles in renal allografts. | 1998 | Transplant. Proc. | pmid:9636510 |