MeSH term | MeSH ID | Detail |
---|---|---|
Acne Vulgaris | D000152 | 35 associated lipids |
Abortion, Spontaneous | D000022 | 12 associated lipids |
Abnormalities, Multiple | D000015 | 13 associated lipids |
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Holtbäck U and Eklöf AC | Mechanism of FK 506/520 action on rat renal proximal tubular Na+, K+-ATPase activity. | 1999 | Kidney Int. | pmid:10469369 |
MacFarlane GD et al. | Analytical validation of the PRO-Trac II ELISA for the determination of tacrolimus (FK506) in whole blood. | 1999 | Clin. Chem. | pmid:10471647 |
Hohl CM and Altschuld RA | FK506 alters sarcoplasmic reticulum calcium release in neonatal piglet cardiac myocytes. | 1999 | Pediatr. Res. | pmid:10473047 |
Medina J et al. | Cytokine profile of human bronchoalveolar macrophages and bronchial epithelial cells in response to inhalation particles of the cyclosporine derivative IMM 125. | 1999 | Inhal Toxicol | pmid:10477442 |
Herrero JI et al. | Conversion of liver transplant recipients on cyclosporine with renal impairment to mycophenolate mofetil. | 1999 | Liver Transpl Surg | pmid:10477843 |
Perry SS et al. | Direct effects of cyclosporin A on proliferation of hematopoietic stem and progenitor cells. | 1999 Jul-Aug | Cell Transplant | pmid:10478713 |
Christner C et al. | Synthesis and cytotoxic evaluation of cycloheximide derivatives as potential inhibitors of FKBP12 with neuroregenerative properties. | 1999 | J. Med. Chem. | pmid:10479292 |
Chan MA et al. | Triptolide is more effective in preventing T cell proliferation and interferon-gamma production than is FK506. | 1999 | Phytother Res | pmid:10479754 |
Fredericks S and Holt DW | TGF-beta quantitation can be tricky. | 1999 | Transplantation | pmid:10480399 |
Hughes JR et al. | Blood levels of TGFbeta1 in liver transplant recipients receiving either tacrolimus or micro-emulsified cyclosporine. | 1999 | Transplantation | pmid:10480422 |
Hodge S et al. | Postinoculation PMPA treatment, but not preinoculation immunomodulatory therapy, protects against development of acute disease induced by the unique simian immunodeficiency virus SIVsmmPBj. | 1999 | J. Virol. | pmid:10482616 |
Fleischer AB | Treatment of atopic dermatitis: role of tacrolimus ointment as a topical noncorticosteroidal therapy. | 1999 | J. Allergy Clin. Immunol. | pmid:10482864 |
Mookerjee B et al. | Salvage therapy for refractory chronic graft-versus-host disease with mycophenolate mofetil and tacrolimus. | 1999 | Bone Marrow Transplant. | pmid:10482936 |
Otsu S et al. | [T cell non-depleted bone marrow transplantation for primary refractory erythroleukemia using a partially HLA-mismatched related donor]. | 1999 | Rinsho Ketsueki | pmid:10483142 |
Tsuji-Takayama K et al. | Interleukin-18 induces interferon-gamma production through NF-kappaB and NFAT activation in murine T helper type 1 cells. | 1999 | Cell. Immunol. | pmid:10486154 |
Pinna AD et al. | Unusual presentation of graft-versus-host disease in pediatric liver transplant recipients: evidence of late and recurrent disease. | 1999 | Pediatr Transplant | pmid:10487286 |
Muthuswamy SK et al. | Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers. | 1999 | Mol. Cell. Biol. | pmid:10490623 |
Ahlers C et al. | Cyclosporin A inhibits Ca2+-mediated upregulation of the DNA repair enzyme DNA polymerase beta in human peripheral blood mononuclear cells. | 1999 | Eur. J. Biochem. | pmid:10491144 |
Sata M and Walsh K | Cyclosporine downregulates Fas ligand expression on vascular endothelial cells: implication for accelerated vasculopathy by immunosuppressive therapy. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10491310 |
Yeh CN et al. | Acute overdoses of tacrolimus (FK 506). | 1999 | Dig. Dis. Sci. | pmid:10492148 |