tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Ileus D045823 3 associated lipids
Rectal Diseases D012002 1 associated lipids
Angiolymphoid Hyperplasia with Eosinophilia D000796 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Landy J and Hart AL Commentary: short-term efficacy of tacrolimus in steroid-refractory ulcerative colitis. 2013 Aliment. Pharmacol. Ther. pmid:23336680
Hirai F et al. Letter: short-term efficacy of tacrolimus in steroid-refractory ulcerative colitis. 2013 Aliment. Pharmacol. Ther. pmid:23336690
Schmidt KJ et al. Letter: short-term efficacy of tacrolimus in steroid-refractory ulcerative colitis - authors' reply. 2013 Aliment. Pharmacol. Ther. pmid:23336691
Baumgart DC et al. Rescue therapy with tacrolimus is effective in patients with severe and refractory inflammatory bowel disease. 2003 Aliment. Pharmacol. Ther. pmid:12755840
Yamamoto T et al. Tacrolimus vs. anti-tumour necrosis factor agents for moderately to severely active ulcerative colitis: a retrospective observational study. 2016 Aliment. Pharmacol. Ther. pmid:26762838
Ierardi E et al. Oral tacrolimus long-term therapy in patients with Crohn's disease and steroid resistance. 2001 Aliment. Pharmacol. Ther. pmid:11207512
Travis S Review article: saving the colon in severe colitis - the case for medical therapy. 2006 Aliment. Pharmacol. Ther. pmid:16961749
Romano C et al. Oral tacrolimus (FK 506) in refractory paediatric ulcerative colitis. 2010 Aliment. Pharmacol. Ther. pmid:20148798
McSharry K et al. Systematic review: the role of tacrolimus in the management of Crohn's disease. 2011 Aliment. Pharmacol. Ther. pmid:21999607
Beckebaum S et al. Renal function and cardiovascular risk profile after conversion from ciclosporin to tacrolimus: prospective study in 80 liver transplant recipients. 2009 Aliment. Pharmacol. Ther. pmid:19624550
Herrlinger KR et al. Infliximab as rescue medication for patients with severe ulcerative/indeterminate colitis refractory to tacrolimus. 2010 Aliment. Pharmacol. Ther. pmid:20175769
Schwrer H et al. Pantoprazole and cyclosporine or tacrolimus. 2001 Aliment. Pharmacol. Ther. pmid:11284790
Yamamoto T et al. Letter: which patient profile for tacrolimus in ulcerative colitis? Authors' reply. 2016 Aliment. Pharmacol. Ther. pmid:27137731
Laharie D and Poullenot F Letter: which patient profile for tacrolimus in ulcerative colitis? 2016 Aliment. Pharmacol. Ther. pmid:27137730
Lawrance IC and Copeland TS Rectal tacrolimus in the treatment of resistant ulcerative proctitis. 2008 Aliment. Pharmacol. Ther. pmid:18761706
Liberal R et al. Expert clinical management of autoimmune hepatitis in the real world. 2017 Aliment. Pharmacol. Ther. pmid:28004405
Segal JP et al. Systematic review with meta-analysis: the management of chronic refractory pouchitis with an evidence-based treatment algorithm. 2017 Aliment. Pharmacol. Ther. pmid:28008631
Yamamoto T et al. Editorial: tacrolimus vs. anti-tumour necrosis factor agents for moderately to severely active ulcerative colitis--authors' reply. 2016 Aliment. Pharmacol. Ther. pmid:27040167
Taylor KM and Sparrow MP Editorial: tacrolimus vs. anti-tumour necrosis factor agents for moderately to severely active ulcerative colitis. 2016 Aliment. Pharmacol. Ther. pmid:27040166
Nakase H et al. Cytomegalovirus affects clinical outcome of infliximab in ulcerative colitis refractory to tacrolimus. 2010 Aliment. Pharmacol. Ther. pmid:20636704