| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ileus | D045823 | 3 associated lipids |
| Rectal Diseases | D012002 | 1 associated lipids |
| Angiolymphoid Hyperplasia with Eosinophilia | D000796 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Pharmacol. Exp. Ther. (1)
- Am. J. Physiol. Renal Physiol. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shin TH et al. | Formulation and in vivo pharmacokinetic evaluation of ethyl cellulose-coated sustained release multiple-unit system of tacrolimus. | 2018 | Int. J. Biol. Macromol. | pmid:29277422 |
| Moriguchi S et al. | Reduced expression of Na/Ca exchangers is associated with cognitive deficits seen in Alzheimer's disease model mice. | 2018 | Neuropharmacology | pmid:29274751 |
| Gaynor JJ and Ciancio G | The Importance of Using Serially Measured Tacrolimus Clearance Values, Especially During the Early Posttransplantation Period. | 2018 | Transplantation | pmid:29271869 |
| Ohara M et al. | Myasthenia Gravis Complicated with Peripheral T-cell Lymphoma, Not Otherwise Specified (PTCL-NOS), Following Thymectomy and Longstanding Tacrolimus Therapy. | 2018 | Intern. Med. | pmid:29269644 |
| Karagun BS et al. | Eye Movement Disorders Following Allogeneic Bone Marrow Transplantation on FK506 (Tacrolimus) and Ganciclovir. | 2018 | J. Pediatr. Hematol. Oncol. | pmid:28731920 |
| Komura Y et al. | Economic assessment of actual prescription of drugs for treatment of atopic dermatitis: Differences between dermatology and pediatrics in large-scale receipt data. | 2018 | J. Dermatol. | pmid:29168213 |
| Cho EJ et al. | Performance of the Dimension TAC assay and comparison of multiple platforms for the measurement of tacrolimus. | 2018 | J. Clin. Lab. Anal. | pmid:29148096 |
| Sir G et al. | Antagonistic Effect of Oxytocin and Tacrolimus Combination on Adipose Tissue - Derived Mesenchymal Stem Cells: Antagonistic effect of oxytocin and tacrolimus. | 2018 | Biomed. Pharmacother. | pmid:29136956 |
| Kirchhof J et al. | Learned immunosuppressive placebo responses in renal transplant patients. | 2018 | Proc. Natl. Acad. Sci. U.S.A. | pmid:29610294 |
| Kojima CA et al. | Sirolimus Associated with Tacrolimus at Low Doses in Elderly Kidney Transplant Patients: A Prospective Randomized Controlled Trial. | 2018 | Exp Clin Transplant | pmid:28836934 |
| Fonseca ACRG et al. | Calcineurin is an important factor involved in glucose uptake in human adipocytes. | 2018 | Mol. Cell. Biochem. | pmid:29380240 |
| Mithani Z et al. | De Novo Donor-Specific Antibody Formation in Tacrolimus-Based, Mycophenolate Versus Mammalian Target of Rapamycin Immunosuppressive Regimens. | 2018 | Exp Clin Transplant | pmid:28332959 |
| Felipe C et al. | Adequacy of Initial Everolimus Dose, With and Without Calcineurin Inhibitors, in Kidney Transplant Recipients. | 2018 | Ther Drug Monit | pmid:29271815 |
| Kimura Y et al. | Profiling the immunotoxicity of chemicals based on in vitro evaluation by a combination of the Multi-ImmunoTox assay and the IL-8 Luc assay. | 2018 | Arch. Toxicol. | pmid:29594315 |
| Vandenbussche C et al. | Tacrolimus-induced nephrotoxicity in mice is associated with microRNA deregulation. | 2018 | Arch. Toxicol. | pmid:29362864 |
| Pflugrad H et al. | Longterm calcineurin inhibitor therapy and brain function in patients after liver transplantation. | 2018 | Liver Transpl. | pmid:29156491 |
| Loeschenberger B et al. | Calcineurin inhibitor-induced complement system activation via ERK1/2 signalling is inhibited by SOCS-3 in human renal tubule cells. | 2018 | Eur. J. Immunol. | pmid:29143318 |
| Liu YJ et al. | Pooled analysis of the comparative efficacy between tacrolimus and infliximab for ulcerative colitis. | 2018 | Medicine (Baltimore) | pmid:30095612 |
| Garaix F et al. | Tacrolimus Granules for Oral Suspension as Post-Transplant Immunosuppression in Routine Medical Practice in France: The OPTIMOD Study. | 2018 | Ann. Transplant. | pmid:30093607 |
| Li P et al. | Risk factors for BK virus infection in living-donor renal transplant recipients: a single-center study from China. | 2018 | Ren Fail | pmid:30052479 |
| Özçakar ZB et al. | Transplantation within the era of anti-IL-1 therapy: case series of five patients with familial Mediterranean fever-related amyloidosis. | 2018 | Transpl. Int. | pmid:29957882 |
| Chao YH et al. | Tolerogenic β2-glycoprotein I DNA vaccine and FK506 as an adjuvant attenuates experimental obstetric antiphospholipid syndrome. | 2018 | PLoS ONE | pmid:29894515 |
| Krogstad V et al. | Determination of Tacrolimus Concentration and Protein Expression of P-Glycoprotein in Single Human Renal Core Biopsies. | 2018 | Ther Drug Monit | pmid:29578937 |
| Rigo-Bonnin R et al. | Different top-down approaches to estimate measurement uncertainty of whole blood tacrolimus mass concentration values. | 2018 | Clin. Biochem. | pmid:29750938 |
| Strohbehn GW et al. | Large-Scale Variability of Inpatient Tacrolimus Therapeutic Drug Monitoring at an Academic Transplant Center: A Retrospective Study. | 2018 | Ther Drug Monit | pmid:29750738 |
| Sablik KA et al. | Tacrolimus intra-patient variability is not associated with chronic active antibody mediated rejection. | 2018 | PLoS ONE | pmid:29746495 |
| Tang JT et al. | A Low Fixed Tacrolimus Starting Dose Is Effective and Safe in Chinese Renal Transplantation Recipients. | 2018 | Ann. Transplant. | pmid:29735966 |
| Cai W et al. | Limited Sampling Strategy for Estimating Mycophenolic Acid Exposure on Day 7 Post-Transplant for Two Mycophenolate Mofetil Formulations Derived From 20 Chinese Renal Transplant Recipients. | 2018 | Transplant. Proc. | pmid:29735215 |
| Chung YW et al. | Tacrolimus-Induced Apoptosis is Mediated by Endoplasmic Reticulum-derived Calcium-dependent Caspases-3,-12 in Jurkat Cells. | 2018 | Transplant. Proc. | pmid:29731088 |
| Zhang Y and Zhang R | Recent advances in analytical methods for the therapeutic drug monitoring of immunosuppressive drugs. | 2018 | Drug Test Anal | pmid:28851030 |
| Kaya Z et al. | Tacrolimus-Induced Autoimmune Hemolytic Anemia in a Previously Reported Child With History of Thrombocytopenia Following Liver Transplant. | 2018 | Exp Clin Transplant | pmid:29633932 |
| Nanmoku K et al. | Steroid Withdrawal Using Everolimus in ABO-Incompatible Kidney Transplant Recipients With Post-Transplant Diabetes Mellitus. | 2018 | Transplant. Proc. | pmid:29631750 |
| Thishya K et al. | Artificial neural network model for predicting the bioavailability of tacrolimus in patients with renal transplantation. | 2018 | PLoS ONE | pmid:29621269 |
| Riva N et al. | Survival Time to Biopsy-Proven Acute Rejection and Tacrolimus Adverse Drug Reactions in Pediatric Liver Transplantation. | 2018 | Ther Drug Monit | pmid:29621122 |
| Youssef A et al. | Angiolymphoid hyperplasia with eosinophilia: a case report. | 2018 | J Med Case Rep | pmid:29606120 |
| Goto T et al. | Prospective observational study on the first 51 cases of peripheral blood stem cell transplantation from unrelated donors in Japan. | 2018 | Int. J. Hematol. | pmid:29027623 |
| Chen ZH et al. | Adenovirus-mediated OX40Ig gene transfer induces long-term survival of orthotopic liver allograft in rats. | 2018 | Transpl. Immunol. | pmid:29454984 |
| Liu J et al. | Donor and recipient P450 gene polymorphisms influence individual pharmacological effects of tacrolimus in Chinese liver transplantation patients. | 2018 | Int. Immunopharmacol. | pmid:29454235 |
| Choi CB et al. | Outcomes of multitarget therapy using mycophenolate mofetil and tacrolimus for refractory or relapsing lupus nephritis. | 2018 | Lupus | pmid:29448881 |
| Woodworth MH et al. | Tacrolimus concentration to dose ratio in solid organ transplant patients treated with fecal microbiota transplantation for recurrent Clostridium difficile infection. | 2018 | Transpl Infect Dis | pmid:29446866 |
| Konma J et al. | Efficacy and safety of combination therapy with prednisolone and oral tacrolimus for progressive interstitial pneumonia with systemic sclerosis: A retrospective study. | 2018 | Mod Rheumatol | pmid:29442534 |
| Buchholz BM et al. | Role of colectomy in preventing recurrent primary sclerosing cholangitis in liver transplant recipients. | 2018 | World J. Gastroenterol. | pmid:30065563 |
| Lloberas N et al. | The combination of CYP3A4*22 and CYP3A5*3 single-nucleotide polymorphisms determines tacrolimus dose requirement after kidney transplantation. | 2017 | Pharmacogenet. Genomics | pmid:28704257 |
| Lombardi A et al. | Impaired mitochondrial calcium uptake caused by tacrolimus underlies beta-cell failure. | 2017 | Cell Commun. Signal | pmid:29132395 |
| Gooptu M and Koreth J | Better acute graft--host disease outcomes for allogeneic transplant recipients in the modern era: a tacrolimus effect? | 2017 | Haematologica | pmid:28458253 |
| Zhang X et al. | Influence of IL-18 and IL-10 Polymorphisms on Tacrolimus Elimination in Chinese Lung Transplant Patients. | 2017 | Dis. Markers | pmid:28246425 |
| D'Avola D et al. | Cardiovascular morbidity and mortality after liver transplantation: The protective role of mycophenolate mofetil. | 2017 | Liver Transpl. | pmid:28160394 |
| Andreu F et al. | A New CYP3A5*3 and CYP3A4*22 Cluster Influencing Tacrolimus Target Concentrations: A Population Approach. | 2017 | Clin Pharmacokinet | pmid:28050888 |
| Olmedo MartÃn RV et al. | Medium to long-term efficacy and safety of oral tacrolimus in moderate to severe steroid refractory ulcerative colitis. | 2017 | Rev Esp Enferm Dig | pmid:28617029 |
| Chucair-Elliott AJ et al. | Colony Stimulating Factor-1 Receptor Expressing Cells Infiltrating the Cornea Control Corneal Nerve Degeneration in Response to HSV-1 Infection. | 2017 | Invest. Ophthalmol. Vis. Sci. | pmid:28903153 |