| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ileus | D045823 | 3 associated lipids |
| Rectal Diseases | D012002 | 1 associated lipids |
| Angiolymphoid Hyperplasia with Eosinophilia | D000796 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Miyauchi T et al. | Effect of donor-specific splenocytes via portal vein and FK506 in rat small bowel transplantation. | 1998 | Transplantation | pmid:9448139 |
| Rosen HR et al. | Significance of early aminotransferase elevation after liver transplantation. | 1998 | Transplantation | pmid:9448146 |
| Connor A et al. | Generic tacrolimus in renal transplantation: trough blood concentration as a surrogate for drug exposure. | 2012 | Transplantation | pmid:23318306 |
| Koprak S et al. | Depletion of the mature CD4+8- thymocyte subset by FK506 analogs correlates with their immunosuppressive and calcineurin inhibitory activities. | 1996 | Transplantation | pmid:8623162 |
| Stevens RB et al. | Randomized trial of single-dose versus divided-dose rabbit anti-thymocyte globulin induction in renal transplantation: an interim report. | 2008 | Transplantation | pmid:18497677 |
| Gurk-Turner C et al. | Thymoglobulin dose optimization for induction therapy in high risk kidney transplant recipients. | 2008 | Transplantation | pmid:18497682 |
| Selzner N et al. | Antiviral treatment of recurrent hepatitis C after liver transplantation: predictors of response and long-term outcome. | 2009 | Transplantation | pmid:19935376 |
| Rush DN et al. | Factors associated with progression of interstitial fibrosis in renal transplant patients receiving tacrolimus and mycophenolate mofetil. | 2009 | Transplantation | pmid:19935461 |
| Gayowski T et al. | Orthotopic liver transplantation in high-risk patients: risk factors associated with mortality and infectious morbidity. | 1998 | Transplantation | pmid:9500623 |
| Arns W et al. | Pharmacokinetics and Clinical Outcomes of Generic Tacrolimus (Hexal) Versus Branded Tacrolimus in De Novo Kidney Transplant Patients: A Multicenter, Randomized Trial. | 2017 | Transplantation | pmid:28658202 |
| Kim YI et al. | Stimulation of liver regeneration by pretreatment with azathioprine as well as cyclosporine and FK506. | 1992 | Transplantation | pmid:1373539 |
| Ashokkumar C et al. | Allospecific CD154+ T-cytotoxic memory cells identify recipients experiencing acute cellular rejection after renal transplantation. | 2011 | Transplantation | pmid:21747326 |
| Cosio FG et al. | Comparison of low versus high tacrolimus levels in kidney transplantation: assessment of efficacy by protocol biopsies. | 2007 | Transplantation | pmid:17318073 |
| Budde K et al. | Conversion from mycophenolate mofetil to enteric-coated mycophenolate sodium in maintenance renal transplant recipients receiving tacrolimus: clinical, pharmacokinetic, and pharmacodynamic outcomes. | 2007 | Transplantation | pmid:17318074 |
| Casey MJ et al. | Prolonged immunosuppression preserves nonsensitization status after kidney transplant failure. | 2014 | Transplantation | pmid:24717218 |
| Stifft F et al. | Lower variability in 24-hour exposure during once-daily compared to twice-daily tacrolimus formulation in kidney transplantation. | 2014 | Transplantation | pmid:24686426 |
| Shibutani S et al. | Effects of immunosuppressants on induction of regulatory cells after intratracheal delivery of alloantigen. | 2005 | Transplantation | pmid:15849542 |
| Peloso LJ et al. | The serum concentration of tacrolimus after ingesting omeprazole: a pilot study. | 2014 | Transplantation | pmid:25221905 |
| Jain A et al. | Pharmacokinetics of tacrolimus in living donor liver transplant and deceased donor liver transplant recipients. | 2008 | Transplantation | pmid:18347534 |
| Kessler M et al. | A renal allograft recipient with late recurrence of focal and segmental glomerulosclerosis after switching from cyclosporine to tacrolimus. | 1999 | Transplantation | pmid:10071045 |
| Robertsen I et al. | Use of generic tacrolimus in elderly renal transplant recipients: precaution is needed. | 2015 | Transplantation | pmid:25148382 |
| Mor E et al. | Late-onset acute rejection in orthotopic liver transplantation--associated risk factors and outcome. | 1992 | Transplantation | pmid:1279849 |
| Hirano Y et al. | The effects of FK506 and cyclosporine on the exocrine function of the rat pancreas. | 1992 | Transplantation | pmid:1279850 |
| van Rijen MM et al. | CD154 is expressed during treatment with calcineurin inhibitors after organ transplantation. | 2002 | Transplantation | pmid:12042657 |
| di Francesco F et al. | One year follow-up of steroid-free immunosuppression plus everolimus in isolated pancreas transplantation. | 2008 | Transplantation | pmid:18946356 |
| Mahé E et al. | Drug-induced hypersensitivity syndrome associated with primary Epstein-Barr virus and human herpesvirus 6 infections in a child intestinal transplant recipient. | 2004 | Transplantation | pmid:14966435 |
| Paramesh AS et al. | Thrombotic microangiopathy associated with combined sirolimus and tacrolimus immunosuppression after intestinal transplantation. | 2004 | Transplantation | pmid:14724447 |
| Boillot O et al. | Reversal of early acute rejection with increased doses of tacrolimus in liver transplantation: a pilot study. | 1998 | Transplantation | pmid:9825815 |
| Jain AB et al. | Comparative incidence of de novo nonlymphoid malignancies after liver transplantation under tacrolimus using surveillance epidemiologic end result data. | 1998 | Transplantation | pmid:9825817 |
| Opelz G | Comparison of FK506 and cyclosporine. | 1996 | Transplantation | pmid:8830844 |
| Zhao W et al. | Pharmacokinetic interaction between tacrolimus and amlodipine in a renal transplant child. | 2012 | Transplantation | pmid:22450597 |
| Yoshimura N et al. | Effect of a new immunosuppressive agent, FK506, on human lymphocyte responses in vitro. I. Inhibition of expression of alloantigen-activated suppressor cells, as well as induction of alloreactivity. | 1989 | Transplantation | pmid:2465592 |
| Jacobson PA et al. | Genetic and clinical determinants of early, acute calcineurin inhibitor-related nephrotoxicity: results from a kidney transplant consortium. | 2012 | Transplantation | pmid:22334041 |
| Schneeberger S et al. | Cytomegalovirus-related complications in human hand transplantation. | 2005 | Transplantation | pmid:16123716 |
| Abadja F et al. | Impact of mycophenolic acid and tacrolimus on Th17-related immune response. | 2011 | Transplantation | pmid:21818055 |
| Ciancio G et al. | A randomized trial of three renal transplant induction antibodies: early comparison of tacrolimus, mycophenolate mofetil, and steroid dosing, and newer immune-monitoring. | 2005 | Transplantation | pmid:16123718 |
| Jain AB et al. | A prospective randomized trial of tacrolimus and prednisone versus tacrolimus, prednisone, and mycophenolate mofetil in primary adult liver transplant recipients: an interim report. | 1998 | Transplantation | pmid:9846530 |
| Ochiai T et al. | Optimal serum trough levels of FK506 in renal allotransplantation of the beagle dog. | 1989 | Transplantation | pmid:2474208 |
| Ochiai T et al. | Effects of combination treatment with FK506 and cyclosporine on survival time and vascular changes in renal-allograft-recipient dogs. | 1989 | Transplantation | pmid:2474209 |
| Macedo C et al. | Long-term effects of alemtuzumab on regulatory and memory T-cell subsets in kidney transplantation. | 2012 | Transplantation | pmid:22343334 |
| Hariharan S | Case 2: strategies to minimize the use of calcineurin inhibitors (CNIs). | 2002 | Transplantation | pmid:12357988 |
| Wu MJ et al. | Lower variability of tacrolimus trough concentration after conversion from prograf to advagraf in stable kidney transplant recipients. | 2011 | Transplantation | pmid:21912349 |
| Schena FP et al. | Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial. | 2009 | Transplantation | pmid:19155978 |
| Fridell JA et al. | Causes of mortality beyond 1 year after primary pediatric liver transplant under tacrolimus. | 2002 | Transplantation | pmid:12499888 |
| Aw MM et al. | Basiliximab (Simulect) for the treatment of steroid-resistant rejection in pediatric liver transpland recipients: a preliminary experience. | 2003 | Transplantation | pmid:12660504 |
| Uchikoshi F et al. | Restoration of immune abnormalities in diabetic BB rats after pancreas transplantation. I. Macrochimerism of donor-graft-derived RT6+ T cells responsible for restoration of immune responsiveness and suppression of autoimmune reaction. | 1996 | Transplantation | pmid:8669109 |
| Gruessner RW et al. | Portal donor-specific blood transfusion and mycophenolate mofetil allow steroid avoidance and tacrolimus dose reduction with sustained levels of chimerism in a pig model of intestinal transplantation. | 2004 | Transplantation | pmid:15239611 |
| Macphee IA et al. | Tacrolimus pharmacogenetics: the CYP3A5*1 allele predicts low dose-normalized tacrolimus blood concentrations in whites and South Asians. | 2005 | Transplantation | pmid:15729180 |
| Baggio B et al. | Relationship between plasma phospholipid polyunsaturated fatty acid composition and bone disease in renal transplantation. | 2005 | Transplantation | pmid:16314806 |
| Margreiter R et al. | A double-hand transplant can be worth the effort! | 2002 | Transplantation | pmid:12134104 |