| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ileus | D045823 | 3 associated lipids |
| Rectal Diseases | D012002 | 1 associated lipids |
| Angiolymphoid Hyperplasia with Eosinophilia | D000796 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fellermann K et al. | Tacrolimus: a new immunosuppressant for steroid refractory inflammatory bowel disease. | 2001 | Transplant. Proc. | pmid:11377517 |
| Salizzoni M et al. | Tacrolimus-based dual therapy is as efficacious and safe as the conventional tacrolimus-based triple therapy in liver transplantation. | 2001 | Transplant. Proc. | pmid:11377521 |
| Langrehr JM et al. | Chronic rejection after orthotopic liver transplantation is increased under induction therapy with interleukin-2 receptor antibody BT563. | 2001 | Transplant. Proc. | pmid:11377531 |
| Migita K and Eguchi K | FK 506-mediated T-cell apoptosis induction. | 2001 | Transplant. Proc. | pmid:11377532 |
| Nakache R et al. | Management of massive proteinuria following renal transplantation with mycophenolate mofetil and blood pressure normalization. | 2001 | Transplant. Proc. | pmid:11377533 |
| Nakatani T et al. | Effect of tacrolimus on the gene expression of renin and endothelin in the rat kidney. | 2001 | Transplant. Proc. | pmid:11377534 |
| Schweizer RT and Meisterling LD | Tolerability of mycophenolate mofetil in organ transplant recipients. | 2001 | Transplant. Proc. | pmid:11377540 |
| Langrehr JM et al. | Quadruple versus dual tacrolimus-based induction after liver transplantation: a prospective, randomized trial. | 2001 | Transplant. Proc. | pmid:11377549 |
| Nagashima N et al. | Immunocompetence assay for net effect of combined immunosuppression. | 2001 | Transplant. Proc. | pmid:11377556 |
| Chariat MN et al. | Basiliximab in the therapy of acute rejection after organ transplantation. | 2001 | Transplant. Proc. | pmid:11377567 |
| Molinaro M et al. | Pharmacokinetics of tacrolimus during the early phase after heart transplantation. | 2001 | Transplant. Proc. | pmid:11377570 |
| McCarter JF et al. | FK 506 protects brain tissue in animal models of stroke. | 2001 | Transplant. Proc. | pmid:11377571 |
| van Gelder T et al. | ATP-binding cassette transporters and calcineurin inhibitors: potential clinical implications. | 2001 | Transplant. Proc. | pmid:11377580 |
| Sandborn WJ | Transcending conventional therapies: the role of biologic and other novel therapies. | 2001 | Inflamm. Bowel Dis. | pmid:11380043 |
| Teixeira R et al. | Management of recurrent hepatitis C after liver transplantation. | 2001 | J. Viral Hepat. | pmid:11380792 |
| Kooman JP et al. | A comparison between office and ambulatory blood pressure measurements in renal transplant patients with chronic transplant nephropathy. | 2001 | Am. J. Kidney Dis. | pmid:11382685 |
| Barten MJ et al. | Flow cytometric quantitation of calcium-dependent and -independent mitogen-stimulation of T cell functions in whole blood: inhibition by immunosuppressive drugs in vitro. | 2001 | J. Immunol. Methods | pmid:11384672 |
| Wakugawa M et al. | Interferon-gamma-induced RANTES production by human keratinocytes is enhanced by IL-1beta, TNF-alpha, IL-4 and IL-13 and is inhibited by dexamethasone and tacrolimus. | 2001 | Dermatology (Basel) | pmid:11385231 |
| Goffin E et al. | Osteoporosis after organ transplantation. | 2001 | Lancet | pmid:11386322 |
| Boillot O et al. | Low rejection rates with tacrolimus-based dual and triple regimens following liver transplantation. | 2001 | Clin Transplant | pmid:11389705 |
| Utsugi R et al. | Induction of transplantation tolerance with a short course of tacrolimus (FK506): I. Rapid and stable tolerance to two-haplotype fully mhc-mismatched kidney allografts in miniature swine. | 2001 | Transplantation | pmid:11391221 |
| Yin DP et al. | Lewis rat pancreas, but not cardiac xenografts, are resistant to anti-gal antibody mediated hyperacute rejection. | 2001 | Transplantation | pmid:11391223 |
| Karasu Z et al. | Acute tacrolimus overdose and treatment with phenytoin in liver transplant recipients. | 2001 | J Okla State Med Assoc | pmid:11392178 |
| Maesaki S | [Molecular mechanize and clinical feature of azole-resistant Candida albicans strains and new strategy of treatment]. | 2001 | Jpn J Antibiot | pmid:11392683 |
| Tuteja S et al. | The effect of gut metabolism on tacrolimus bioavailability in renal transplant recipients. | 2001 | Transplantation | pmid:11397967 |
| Otsuka M et al. | Long-term results of donor-specific blood transfusion with cyclosporine in living related kidney transplantation. | 2001 | Nephron | pmid:11399917 |
| Bekersky I et al. | Comparative tacrolimus pharmacokinetics: normal versus mildly hepatically impaired subjects. | 2001 | J Clin Pharmacol | pmid:11402631 |
| Penson MG et al. | Safety and efficacy of pravastatin therapy for the prevention of hyperlipidemia in pediatric and adolescent cardiac transplant recipients. | 2001 | J. Heart Lung Transplant. | pmid:11404165 |
| Allen A et al. | Significant absorption of topical tacrolimus in 3 patients with Netherton syndrome. | 2001 | Arch Dermatol | pmid:11405764 |
| Diaz-Romero J et al. | Coexpression of CD4 and CD8alpha on rat T-cells in whole blood: a sensitive marker for monitoring T-cell immunosuppressive drugs. | 2001 | J. Immunol. Methods | pmid:11406149 |
| Osako M et al. | Alloimmune response may be involved in neointimal hyperplasia in cryopreserved aortic allografts. | 2001 | Transplant. Proc. | pmid:11406250 |
| Faivre L et al. | FK 506 dose in transplantation: from theory to practice. | 2001 | Transplant. Proc. | pmid:11406256 |
| Chan KL et al. | Porcine small bowel transplantation with FK506 as a single immunosuppressant. | 2001 | Transplant. Proc. | pmid:11406260 |
| Charpentier B | An induction versus no-induction protocol in anticalcineurin-based immunosuppression using very low-dose steroids. | 2001 | Transplant. Proc. | pmid:11406262 |
| Weir MR | Methods and outcomes of calcineurin inhibitor reduction or withdrawal in patients with chronic allograft nephropathy after the first year posttransplantation. | 2001 | Transplant. Proc. | pmid:11406264 |
| Land W et al. | Mycophenolate mofetil monotherapy: an optimal, safe, and efficacious immunosuppressive maintenance regimen in kidney transplant patients. | 2001 | Transplant. Proc. | pmid:11406265 |
| Sakuma S et al. | Tacrolimus suppressed the production of cytokines involved in atopic dermatitis by direct stimulation of human PBMC system. (Comparison with steroids). | 2001 | Int. Immunopharmacol. | pmid:11407316 |
| Shimoishi K et al. | FK506 (tacrolimus) increases rat alpha1-acid glycoprotein expression in liver and primary cultured hepatocytes. | 2001 | Eur. J. Pharmacol. | pmid:11408029 |
| Navarro X et al. | Effects of FK506 on nerve regeneration and reinnervation after graft or tube repair of long nerve gaps. | 2001 | Muscle Nerve | pmid:11410918 |
| Hiroi J | [Pharmacological profile and clinical effect of tacrolimus ointment (Protopic ointment) for atopic dermatitis]. | 2001 | Nippon Yakurigaku Zasshi | pmid:11411345 |
| Kaibori M et al. | FK506, but not cyclosporin A, prevents mitochondrial dysfunction during hypoxia in rat hepatocytes. | 2001 | Life Sci. | pmid:11411802 |
| Sun J et al. | Role for p27(Kip1) in Vascular Smooth Muscle Cell Migration. | 2001 | Circulation | pmid:11413088 |
| Sing A et al. | Molecular diagnosis of an Enterocytozoon bieneusi human genotype C infection in a moderately immunosuppressed human immunodeficiency virus seronegative liver-transplant recipient with severe chronic diarrhea. | 2001 | J. Clin. Microbiol. | pmid:11414246 |
| Kolpak S and Mehler P | Medical issues in treating renal transplant patients. | 2001 | Hosp Pract (1995) | pmid:11419536 |
| Chang RK et al. | Echocardiographic findings of hypertrophic cardiomyopathy in children after orthotopic liver transplantation. | 2001 | Pediatr Transplant | pmid:11422821 |
| Hasegawa T et al. | Oral administration of tacrolimus in the presence of jejunostomy after liver transplantation. | 2001 | Pediatr Transplant | pmid:11422824 |
| Kanoh S et al. | FK506 inhibits Cl- secretion in airway epithelium via calcineurin-independent mechanism. | 2001 | Eur. J. Pharmacol. | pmid:11426833 |
| Mourad M et al. | Pharmacokinetic basis for the efficient and safe use of low-dose mycophenolate mofetil in combination with tacrolimus in kidney transplantation. | 2001 | Clin. Chem. | pmid:11427455 |
| Matsuo N et al. | Tacrolimus inhibits cytokine production and chemical mediator release following antigen stimulation of passively sensitized human lung tissues. | 2001 | Ann. Allergy Asthma Immunol. | pmid:11428741 |
| Ramm K and Plückthun A | High enzymatic activity and chaperone function are mechanistically related features of the dimeric E. coli peptidyl-prolyl-isomerase FkpA. | 2001 | J. Mol. Biol. | pmid:11428902 |
| Lo A et al. | Patterns of cytomegalovirus infection in simultaneous kidney-pancreas transplant recipients receiving tacrolimus, mycophenolate mofetil, and prednisone with ganciclovir prophylaxis. | 2001 | Transpl Infect Dis | pmid:11429034 |
| Tanaka K et al. | FK506 ameliorates the discrimination learning impairment due to preventing the rarefaction of white matter induced by chronic cerebral hypoperfusion in rats. | 2001 | Brain Res. | pmid:11430878 |
| Boldorini R et al. | Molecular characterization and sequence analysis of polyomavirus BKV-strain in a renal-allograft recipient. | 2001 | Hum. Pathol. | pmid:11431722 |
| Dorn GW | Calcineurin inhibition in hypertrophy: back from the dead! | 2001 | Circulation | pmid:11435329 |
| Yamataka A et al. | Bladder transplantation in rats using FK-506. | 2001 | J. Urol. | pmid:11435882 |
| Singleton RH et al. | The immunophilin ligand FK506 attenuates axonal injury in an impact-acceleration model of traumatic brain injury. | 2001 | J. Neurotrauma | pmid:11437083 |
| Kakegawa T et al. | [Effect of rapamycin on cytoplasmic accumulation of hetero nuclear ribonucleoprotein C-like unwinding protein 2]. | 2001 | Jpn J Antibiot | pmid:11439909 |
| Uyeda M et al. | Pentalenolactone I and hygromycin A, immunosuppressants produced by Streptomyces filipinensis and Streptomyces hygroscopicus. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11440152 |
| Volosov A et al. | Simultaneous simple and fast quantification of three major immunosuppressants by liquid chromatography--tandem mass-spectrometry. | 2001 | Clin. Biochem. | pmid:11440728 |
| Satoh S et al. | Chrono and clinical pharmacokinetic study of tacrolimus in continuous intravenous administration. | 2001 | Int. J. Urol. | pmid:11442656 |
| Neal DA et al. | Beneficial effects of converting liver transplant recipients from cyclosporine to tacrolimus on blood pressure, serum lipids, and weight. | 2001 | Liver Transpl. | pmid:11443583 |
| Hurtova M et al. | Successful tacrolimus therapy for a severe recurrence of type 1 autoimmune hepatitis in a liver graft recipient. | 2001 | Liver Transpl. | pmid:11443588 |
| Railson JE et al. | Heat shock protein-56 is induced by cardiotrophin-1 and mediates its hypertrophic effect. | 2001 | J. Mol. Cell. Cardiol. | pmid:11444924 |
| Nowak-Wegrzyn AH et al. | Food allergy after pediatric organ transplantation with tacrolimus immunosuppression. | 2001 | J. Allergy Clin. Immunol. | pmid:11447402 |
| Harmon JV et al. | Experimental short-term immunosuppression after bowel transplantation and donor-specific bone marrow infusion. | 2001 | Arch Surg | pmid:11448397 |
| Taylor DO et al. | Suggested guidelines for the use of tacrolimus in cardiac transplant recipients. | 2001 | J. Heart Lung Transplant. | pmid:11448799 |
| Strassburg CP et al. | Identification of cyclosporine A and tacrolimus glucuronidation in human liver and the gastrointestinal tract by a differentially expressed UDP-glucuronosyltransferase: UGT2B7. | 2001 | J. Hepatol. | pmid:11451170 |
| Nagler A et al. | Amelioration of steroid-resistant chronic graft-versus-host-mediated liver disease via tacrolimus treatment. | 2001 | J. Hematother. Stem Cell Res. | pmid:11454316 |
| Vennarecci G et al. | Apoptosis and rejection in rat intestinal transplantation: correlation with FK506 doses and donor specific bone marrow infusions. | 2001 | Transplantation | pmid:11455248 |
| Papaccio G et al. | Tacrolimus, but not cyclosporine A, significantly increases expression of ICAM-1 and IFN-gamma in the NOD mouse. | 2001 | J. Cell. Biochem. Suppl. | pmid:11455576 |
| Koide K et al. | A synthetic library of cell-permeable molecules. | 2001 | J. Am. Chem. Soc. | pmid:11456541 |
| Jain A et al. | Does tacrolimus offer virtual freedom from chronic rejection after primary liver transplantation? Risk and prognostic factors in 1,048 liver transplantations with a mean follow-up of 6 years. | 2001 | Liver Transpl. | pmid:11460230 |
| Motohashi H et al. | Effects of tacrolimus and cyclosporin A on peptide transporter PEPT1 in Caco-2 cells. | 2001 | Pharm. Res. | pmid:11465431 |
| Parvex P et al. | Reversible encephalopathy associated with tacrolimus in pediatric renal transplants. | 2001 | Pediatr. Nephrol. | pmid:11465799 |
| Sarwal MM et al. | Promising early outcomes with a novel, complete steroid avoidance immunosuppression protocol in pediatric renal transplantation. | 2001 | Transplantation | pmid:11468528 |
| Camirand G et al. | Combined immunosuppression of mycophenolate mofetil and FK506 for myoblast transplantation in mdx mice. | 2001 | Transplantation | pmid:11468532 |
| Squifflet JP et al. | Dose optimization of mycophenolate mofetil when administered with a low dose of tacrolimus in cadaveric renal transplant recipients. | 2001 | Transplantation | pmid:11468536 |
| Theruvath TP et al. | Control of antidonor antibody production with tacrolimus and mycophenolate mofetil in renal allograft recipients with chronic rejection. | 2001 | Transplantation | pmid:11468538 |
| Motohashi H et al. | Expression of peptide transporter following intestinal transplantation in the rat. | 2001 | J. Surg. Res. | pmid:11469900 |
| Hashimoto Y et al. | Novel immunosuppressive effect of FK506 by augmentation of T cell apoptosis. | 2001 | Clin. Exp. Immunol. | pmid:11472421 |
| Miki T et al. | Hamster-to-rat bone marrow xenotransplantation and humoral graft vs. host disease. | 2001 | Xenotransplantation | pmid:11472629 |
| Ahmed M et al. | Quantitation of immunosuppression by tacrolimus using flow cytometric analysis of interleukin-2 and interferon-gamma inhibition in CD8(-) and CD8(+) peripheral blood T cells. | 2001 | Ther Drug Monit | pmid:11477316 |
| Ahsan N et al. | Randomized trial of tacrolimus plus mycophenolate mofetil or azathioprine versus cyclosporine oral solution (modified) plus mycophenolate mofetil after cadaveric kidney transplantation: results at 2 years. | 2001 | Transplantation | pmid:11477347 |
| Andries S et al. | Posttransplant immune hepatitis in pediatric liver transplant recipients: incidence and maintenance therapy with azathioprine. | 2001 | Transplantation | pmid:11477351 |
| Yamataka A et al. | Transplantation of newborn esophagus: an experimental study. | 2001 | J. Pediatr. Surg. | pmid:11479870 |
| Son IJ et al. | No effect of water deprivation for 48 hours on the pharmacokiinetics of intravenous tacrolimus in rats. | 2000 | Res. Commun. Mol. Pathol. Pharmacol. | pmid:11484882 |
| Gianni LM and Sulli MM | Topical tacrolimus in the treatment of atopic dermatitis. | 2001 Jul-Aug | Ann Pharmacother | pmid:11485148 |
| Zager RA et al. | Renal cholesterol accumulation: a durable response after acute and subacute renal insults. | 2001 | Am. J. Pathol. | pmid:11485932 |
| Mück W et al. | Tacrolimus/cerivastatin interaction study in liver transplant recipients. | 2001 | Br J Clin Pharmacol | pmid:11488782 |
| James JA et al. | Tacrolimus is not associated with gingival overgrowth in renal transplant patients. | 2001 | J. Clin. Periodontol. | pmid:11493354 |
| Meyer D et al. | Orthotopic liver/small bowel transplantation in rats: a microsurgical model inducing tolerance. | 2001 | Microsurgery | pmid:11494384 |
| Suzuki Y et al. | [Mesial temporal lobe epilepsy in a patient with Wilson's disease receiving FK506 (tacrolimus) after liver transplantation]. | 2001 | No To Hattatsu | pmid:11494578 |
| Zuberbier T et al. | The ascomycin macrolactam pimecrolimus (Elidel, SDZ ASM 981) is a potent inhibitor of mediator release from human dermal mast cells and peripheral blood basophils. | 2001 | J. Allergy Clin. Immunol. | pmid:11496246 |
| Weir M | Impact of immunosuppressive regimes on posttransplant diabetes mellitus. | 2001 | Transplant. Proc. | pmid:11498201 |
| Eagle DA et al. | Gastroparesis following bone marrow transplantation. | 2001 | Bone Marrow Transplant. | pmid:11498745 |
| Gruessner RW et al. | Bone marrow augmentation in kidney transplantation: a large animal study. | 2001 | Transpl. Int. | pmid:11499905 |
| Hwang KK et al. | FK506 promotes adenosine release from endothelial cells via inhibition of adenosine kinase. | 2001 | Eur. J. Pharmacol. | pmid:11502273 |
| Takatsuki M et al. | Weaning of immunosuppression in living donor liver transplant recipients. | 2001 | Transplantation | pmid:11502975 |
| Lum H et al. | Protein phosphatase 2B inhibitor potentiates endothelial PKC activity and barrier dysfunction. | 2001 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:11504680 |
| Müller WE et al. | Suppression of allograft rejection in the sponge Suberites domuncula by FK506 and expression of genes encoding FK506-binding proteins in allografts. | 2001 | J. Exp. Biol. | pmid:11507104 |