tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Ileus D045823 3 associated lipids
Rectal Diseases D012002 1 associated lipids
Angiolymphoid Hyperplasia with Eosinophilia D000796 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Suda D et al. The effect of bone mass and architecture on mandibular condyle after mandibular distraction. 2017 Oral Surg Oral Med Oral Pathol Oral Radiol pmid:28864292
Ng YZ et al. Fluorescence Polarization Assay for Small Molecule Screening of FK506 Biosynthesized in 96-Well Microtiter Plates. 2017 Biochemistry pmid:28841306
Wiebe C et al. Class II Eplet Mismatch Modulates Tacrolimus Trough Levels Required to Prevent Donor-Specific Antibody Development. 2017 J. Am. Soc. Nephrol. pmid:28729289
Chiramel DM et al. Topical tacrolimus causing gingival hyperplasia: A case report. 2017 Dermatol Ther pmid:27572623
Hou X et al. Overexpression of Fibulin-5 attenuates burn-induced inflammation via TRPV1/CGRP pathway. 2017 Exp. Cell Res. pmid:28602628
Tang JT et al. The pharmacokinetics and pharmacodynamics of mycophenolate mofetil in younger and elderly renal transplant recipients. 2017 Br J Clin Pharmacol pmid:27753146
Kita K and Mano Y Application of volumetric absorptive microsampling device for quantification of tacrolimus in human blood as a model drug of high blood cell partition. 2017 J Pharm Biomed Anal pmid:28601765
Abongwa C et al. Successful treatment of tacrolimus-related pure red cell aplasia and autoimmune hemolytic anemia with rituximab in a pediatric cardiac transplant patient. 2017 Pediatr Blood Cancer pmid:28598573
Wu Z et al. FOXP3 rs3761548 polymorphism is associated with tacrolimus-induced acute nephrotoxicity in renal transplant patients. 2017 Eur. J. Clin. Pharmacol. pmid:27747372
Torres IB et al. Tacrolimus and mycophenolate regimen and subclinical tubulo-interstitial inflammation in low immunological risk renal transplants. 2017 Transpl. Int. pmid:28667664
Miller AK et al. Transmission of Donor-Derived Breast Carcinoma as a Recurrent Mass in a Keratolimbal Allograft. 2017 Cornea pmid:28476053
Nakagawa K et al. Immunosuppressive treatment using tacrolimus promotes pregnancy outcome in infertile women with repeated implantation failures. 2017 Am. J. Reprod. Immunol. pmid:28466977
Ikebe T et al. Hemophagocytic lymphohistiocytosis following influenza vaccination in a patient with aplastic anemia undergoing allogeneic bone marrow stem cell transplantation. 2017 Int. J. Hematol. pmid:28054244
Harada S et al. Complete remission of angiolymphoid hyperplasia with eosinophilia using topical tacrolimus. 2017 Eur J Dermatol pmid:28007668
Zhang L et al. Characterization of calcineurin from Cryptococcus humicola and the application of calcineurin in aluminum tolerance. 2017 BMC Biotechnol. pmid:28356086
Bellon H et al. The Effect of Immunosuppression on Airway Integrity. 2017 Transplantation pmid:28471870
Ferjani H et al. Beneficial effects of mycophenolate mofetil on cardiotoxicity induced by tacrolimus in wistar rats. 2017 Exp. Biol. Med. (Maywood) pmid:26582055
Solari S et al. Sublingual tacrolimus administration provides similar drug exposure to per-oral route employing lower doses in liver transplantation: a pilot study. 2017 Aliment. Pharmacol. Ther. pmid:28261844
Rodríguez-Perálvarez M et al. Maintenance immunosuppression for adults undergoing liver transplantation: a network meta-analysis. 2017 Cochrane Database Syst Rev pmid:28362060
Cui W et al. Therapy of tacrolimus combined with corticosteroids in idiopathic membranous nephropathy. 2017 Braz. J. Med. Biol. Res. pmid:28355356
Chakfe N Commentary on "Tacrolimus Eluting Suture Inhibits Neointimal Hyperplasia: An Experimental In Vivo Study in Rats". 2017 Eur J Vasc Endovasc Surg pmid:28169106
Siponen M et al. Topical tacrolimus, triamcinolone acetonide, and placebo in oral lichen planus: a pilot randomized controlled trial. 2017 Oral Dis pmid:28168769
Vanhove T et al. Response to: 'Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance'. 2017 Br J Clin Pharmacol pmid:28168728
Gao L et al. Low incidence of acute graft-versus-host disease with short-term tacrolimus in haploidentical hematopoietic stem cell transplantation. 2017 Leuk. Res. pmid:28273549
Aschauer C et al. Positioning of Tacrolimus for the Treatment of Diabetic Nephropathy Based on Computational Network Analysis. 2017 PLoS ONE pmid:28060893
Dong Y et al. Risk Factors, Clinical Features, and Treatment Outcomes of Recurrent Mooren Ulcers in China. 2017 Cornea pmid:28060068
de Oliveira JTP et al. Variability index of tacrolimus serum levels in pediatric liver transplant recipients younger than 12 years: Non-adherence or risk of non-adherence? 2017 Pediatr Transplant pmid:29034612
Kim YK et al. New tablet formulation of tacrolimus with smaller interindividual variability may become a better treatment option than the conventional capsule formulation in organ transplant patients. 2017 Drug Des Devel Ther pmid:29033547
Nazeer A et al. Factors leading to dyspepsia in renal transplant recipients. 2017 Pan Afr Med J pmid:29515738
Tamura M et al. [A case of anti-PL-7 antibody positive polymyositis with thrombotic microangiopathy]. 2017 Nihon Rinsho Meneki Gakkai Kaishi pmid:29367529
Komaki Y et al. Pharmacologic therapies for severe steroid refractory hospitalized ulcerative colitis: A network meta-analysis. 2017 J. Gastroenterol. Hepatol. pmid:27957761
Dutta D et al. Recruitment of calcineurin to the TCR positively regulates T cell activation. 2017 Nat. Immunol. pmid:27941787
Perez LE et al. Visilizumab with tacrolimus and methotrexate for GvHD prevention after allogeneic hematopoietic cell transplantation from mismatched unrelated donors. 2017 Bone Marrow Transplant. pmid:27991896
Lee SM et al. Inhibition of acute lethal pulmonary inflammation by the IDO-AhR pathway. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:28673995
Naicker D et al. Nationwide conversion to generic tacrolimus in pediatric kidney transplant recipients. 2017 Pediatr. Nephrol. pmid:28660366
Qi H et al. Integration of parallel C-labeling experiments and in silico pathway analysis for enhanced production of ascomycin. 2017 Biotechnol. Bioeng. pmid:27869289
Gatault P et al. Reduction of Extended-Release Tacrolimus Dose in Low-Immunological-Risk Kidney Transplant Recipients Increases Risk of Rejection and Appearance of Donor-Specific Antibodies: A Randomized Study. 2017 Am. J. Transplant. pmid:27862923
Herz S et al. Checkpoint inhibitors in chronic kidney failure and an organ transplant recipient. 2016 Eur. J. Cancer pmid:27614165
Nakajima A et al. Effectiveness of tacrolimus in comparison with methotrexate or biologics in propensity score-matched patients with rheumatoid arthritis. 2016 Mod Rheumatol pmid:26934454
Knight SR Intrapatient variability in tacrolimus exposure - a useful tool for clinical practice? 2016 Transpl. Int. pmid:27283231
Song JL et al. Minimizing tacrolimus decreases the risk of new-onset diabetes mellitus after liver transplantation. 2016 World J. Gastroenterol. pmid:26877618
Than NN et al. Long-term follow-up of patients with difficult to treat type 1 autoimmune hepatitis on Tacrolimus therapy. 2016 Scand. J. Gastroenterol. pmid:26458216
Malik N et al. A simple office-based procedure for patients with extensive vitiligo. 2016 J. Am. Acad. Dermatol. pmid:27745651
Lee B et al. Appropriate timing of tacrolimus concentration measurements in the emergency department. 2016 Am J Health Syst Pharm pmid:27543574
Komaki Y et al. Efficacy and Safety of Tacrolimus Therapy for Active Ulcerative Colitis; A Systematic Review and Meta-analysis. 2016 J Crohns Colitis pmid:26645641
Gardiner KM et al. Multinational Evaluation of Mycophenolic Acid, Tacrolimus, Cyclosporin, Sirolimus, and Everolimus Utilization. 2016 Ann. Transplant. pmid:26729299
Riegersperger M et al. The Effect of ABCB1 Polymorphisms on Serial Tacrolimus Concentrations in Stable Austrian Long-Term Kidney Transplant Recipients. 2016 Clin. Lab. pmid:28164520
Levitsky J et al. Immunoregulatory Effects of Everolimus on In Vitro Alloimmune Responses. 2016 PLoS ONE pmid:27275747
Baraldo M Meltdose Tacrolimus Pharmacokinetics. 2016 Transplant. Proc. pmid:27109969
Vanhove T et al. High Intrapatient Variability of Tacrolimus Concentrations Predicts Accelerated Progression of Chronic Histologic Lesions in Renal Recipients. 2016 Am. J. Transplant. pmid:27013142