| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ileus | D045823 | 3 associated lipids |
| Rectal Diseases | D012002 | 1 associated lipids |
| Angiolymphoid Hyperplasia with Eosinophilia | D000796 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Morena M et al. | Low-density lipoprotein composition and oxidation are not influenced by calcineurin inhibitors in renal transplant patients. | 2000 | Transplant. Proc. | pmid:11134805 |
| Fischer S et al. | Initial experience of combined immunosuppressive induction therapy with polyclonal antithymocyte antibody, FK 506 (tacrolimus), and prednisolone in clinical liver transplantation. | 2000 | Transplant. Proc. | pmid:11134815 |
| Sam WJ et al. | Population pharmacokinetics of tacrolimus in Asian paediatric liver transplant patients. | 2000 | Br J Clin Pharmacol | pmid:11136292 |
| Sestak K et al. | Tacrolimus-FK506 induced immunosuppression in gnotobiotic piglets. | 2000 | Vet. Immunol. Immunopathol. | pmid:11137126 |
| Michnick SW | Chemical biology beyond binary codes. | 2000 | Chem. Biol. | pmid:11137822 |
| Lopau K et al. | Tacrolimus in acute renal failure: does L-arginine-infusion prevent changes in renal hemodynamics? | 2000 | Transpl. Int. | pmid:11140242 |
| Abraham KA et al. | Hemolytic-uremic syndrome in association with both cyclosporine and tacrolimus. | 2000 | Transpl. Int. | pmid:11140243 |
| Haas M et al. | Hypothyroidism as a cause of tacrolimus intoxication and acute renal failure: a case report. | 2000 | Wien. Klin. Wochenschr. | pmid:11144010 |
| Barone GW et al. | The tolerability of newer immunosuppressive medications in a patient with acute intermittent porphyria. | 2001 | J Clin Pharmacol | pmid:11144989 |
| Bekersky I et al. | Nonclinical and early clinical development of tacrolimus ointment for the treatment of atopic dermatitis. | 2001 | J. Am. Acad. Dermatol. | pmid:11145792 |
| Hanifin JM et al. | Tacrolimus ointment for the treatment of atopic dermatitis in adult patients: part I, efficacy. | 2001 | J. Am. Acad. Dermatol. | pmid:11145793 |
| Soter NA et al. | Tacrolimus ointment for the treatment of atopic dermatitis in adult patients: part II, safety. | 2001 | J. Am. Acad. Dermatol. | pmid:11145794 |
| Paller A et al. | A 12-week study of tacrolimus ointment for the treatment of atopic dermatitis in pediatric patients. | 2001 | J. Am. Acad. Dermatol. | pmid:11145795 |
| Kang S et al. | Long-term safety and efficacy of tacrolimus ointment for the treatment of atopic dermatitis in children. | 2001 | J. Am. Acad. Dermatol. | pmid:11145796 |
| Drake L et al. | The impact of tacrolimus ointment on health-related quality of life of adult and pediatric patients with atopic dermatitis. | 2001 | J. Am. Acad. Dermatol. | pmid:11145797 |
| Vallejo C et al. | Resolution of cyclosporine-induced gingival hyperplasia resistant to azithromycin by switching to tacrolimus. | 2001 | Haematologica | pmid:11146586 |
| Nghiem P | "Topical immunomodulators?": introducing old friends and a new ally, tacrolimus. | 2001 | J. Am. Acad. Dermatol. | pmid:11148486 |
| Butani L and Makker SP | Conversion from tacrolimus to neoral for postrenal transplant diabetes. | 2000 | Pediatr. Nephrol. | pmid:11149106 |
| Gondo H et al. | Acquired Pelger-Huët anomaly in association with concomitant tacrolimus and fluconazole therapy following allogeneic bone marrow transplantation. | 2000 | Bone Marrow Transplant. | pmid:11149744 |
| Remitz A et al. | Tacrolimus ointment reduces staphylococcal colonization of atopic dermatitis lesions. | 2001 | J. Allergy Clin. Immunol. | pmid:11150013 |
| Emre S et al. | Safety and risk of using pediatric donor livers in adult liver transplantation. | 2001 | Liver Transpl. | pmid:11150421 |
| Nagatomo I et al. | Effects of MK-801, dantrolene, and FK506 on convulsive seizures and brain nitric oxide production in seizure-susceptible EL mice. | 2001 | Brain Res. | pmid:11150489 |
| Hamar P et al. | Interleukin-2-dependent mechanisms are involved in the development of glomerulosclerosis after partial renal ablation in rats. | 2001 Mar-Apr | Exp. Nephrol. | pmid:11150862 |
| Bain JR | Peripheral nerve and neuromuscular allotransplantation: current status. | 2000 | Microsurgery | pmid:11150988 |
| Gruber SA et al. | Local drug delivery to composite tissue allografts. | 2000 | Microsurgery | pmid:11150992 |
| König A et al. | Intravascular ultrasound for assessment of coronary allograft vasculopathy. | 2000 | Z Kardiol | pmid:11151792 |
| Kainz A et al. | Review of the course and outcome of 100 pregnancies in 84 women treated with tacrolimus. | 2000 | Transplantation | pmid:11152103 |
| MacDonald AS | Impact of immunosuppressive therapy on hypertension. | 2000 | Transplantation | pmid:11152235 |
| Cather JC et al. | Cyclosporine and tacrolimus in dermatology. | 2001 | Dermatol Clin | pmid:11155577 |
| Tolou-Ghamari Z et al. | In vitro pentamer formation as a biomarker of tacrolimus-related immunosuppressive activity after liver transplantation. | 2000 | Clin. Chem. Lab. Med. | pmid:11156362 |
| Mathis AS and Friedman GS | Coadministration of digoxin with itraconazole in renal transplant recipients. | 2001 | Am. J. Kidney Dis. | pmid:11157404 |
| Prestle J et al. | Overexpression of FK506-binding protein FKBP12.6 in cardiomyocytes reduces ryanodine receptor-mediated Ca(2+) leak from the sarcoplasmic reticulum and increases contractility. | 2001 | Circ. Res. | pmid:11157671 |
| Ligtenberg G et al. | Cardiovascular risk factors in renal transplant patients: cyclosporin A versus tacrolimus. | 2001 | J. Am. Soc. Nephrol. | pmid:11158228 |
| Coupes BM et al. | Plasma transforming growth factor beta(1) and platelet activation: implications for studies in transplant recipients. | 2001 | Nephrol. Dial. Transplant. | pmid:11158413 |
| Hanauer SB and Dassopoulos T | Evolving treatment strategies for inflammatory bowel disease. | 2001 | Annu. Rev. Med. | pmid:11160781 |
| Rose N and Lever A | The rapamycin sensitivity of human T-cell leukaemia virus type I-induced T-cell proliferation is mediated independently of the polypyrimidine motifs in the 5' long terminal repeat. | 2001 | J. Gen. Virol. | pmid:11161283 |
| Peeling J et al. | Effect of FK-506 on inflammation and behavioral outcome following intracerebral hemorrhage in rat. | 2001 | Exp. Neurol. | pmid:11161622 |
| Hofbauer LC et al. | Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11162519 |
| Wakugawa M et al. | Evaluation of mite allergen-induced Th1 and Th2 cytokine secretion of peripheral blood mononuclear cells from atopic dermatitis patients: association between IL-13 and mite-specific IgE levels. | 2001 | J. Dermatol. Sci. | pmid:11164708 |
| Baran DA et al. | Tacrolimus monotherapy in adult cardiac transplant recipients: intermediate-term results. | 2001 | J. Heart Lung Transplant. | pmid:11166613 |
| Tanaka K et al. | Immunosuppressive and non-immunosuppressive immunophilin ligands improve H(2)O(2)-induced cell damage by increasing glutathione levels in NG108-15 cells. | 2001 | Brain Res. | pmid:11166708 |
| Macleod MR et al. | Serum withdrawal causes apoptosis in SHSY 5Y cells. | 2001 | Brain Res. | pmid:11166724 |
| Boulad F et al. | Stem cell transplantation for the treatment of Fanconi anaemia using a fludarabine-based cytoreductive regimen and T-cell-depleted related HLA-mismatched peripheral blood stem cell grafts. | 2000 | Br. J. Haematol. | pmid:11167755 |
| Jørgensen PF et al. | Sirolimus interferes with the innate response to bacterial products in human whole blood by attenuation of IL-10 production. | 2001 | Scand. J. Immunol. | pmid:11169223 |
| Bayguinov O et al. | Muscarinic stimulation increases basal Ca(2+) and inhibits spontaneous Ca(2+) transients in murine colonic myocytes. | 2001 | Am. J. Physiol., Cell Physiol. | pmid:11171588 |
| Manzarbeitia C et al. | Tacrolimus conversion improves hyperlipidemic states in stable liver transplant recipients. | 2001 | Liver Transpl. | pmid:11172391 |
| Shibazaki Y et al. | Effect of the immunosuppressant drug FK506 on neonatal cerebral mitochondrial function and energy metabolism after transient intrauterine ischemia in rats. | 2001 | Brain Res. | pmid:11172783 |
| Panhans-Gross A et al. | Human epidermal Langerhans' cells are targets for the immunosuppressive macrolide tacrolimus (FK506). | 2001 | J. Allergy Clin. Immunol. | pmid:11174203 |
| Hauk PJ and Leung DY | Tacrolimus (FK506): new treatment approach in superantigen-associated diseases like atopic dermatitis? | 2001 | J. Allergy Clin. Immunol. | pmid:11174211 |
| Paller AS | Use of nonsteroidal topical immunomodulators for the treatment of atopic dermatitis in the pediatric population. | 2001 | J. Pediatr. | pmid:11174611 |