MeSH term | MeSH ID | Detail |
---|---|---|
Ileus | D045823 | 3 associated lipids |
Rectal Diseases | D012002 | 1 associated lipids |
Angiolymphoid Hyperplasia with Eosinophilia | D000796 | 1 associated lipids |
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Labrador J et al. | Risk factors for thrombotic microangiopathy in allogeneic hematopoietic stem cell recipients receiving GVHD prophylaxis with tacrolimus plus MTX or sirolimus. | 2014 | Bone Marrow Transplant. | pmid:24566710 |
Singh K et al. | Superiority of rapamycin over tacrolimus in preserving nonhuman primate Treg half-life and phenotype after adoptive transfer. | 2014 | Am. J. Transplant. | pmid:25359003 |
Siebelt M et al. | FK506 protects against articular cartilage collagenous extra-cellular matrix degradation. | 2014 | Osteoarthr. Cartil. | pmid:24561282 |
Tang Q | Pharmacokinetics of therapeutic Tregs. | 2014 | Am. J. Transplant. | pmid:25358900 |
Hamzah S et al. | Pharmacogenotyping of CYP3A5 in predicting dose-adjusted trough levels of tacrolimus among Malaysian kidney-transplant patients. | 2014 | Can. J. Physiol. Pharmacol. | pmid:24383873 |
Amorim J et al. | Tacrolimus-induced neutropenia in a cardiac transplant patient. | 2014 | Pediatr Transplant | pmid:24384051 |
Silva HT et al. | Long-term follow-up of a phase III clinical trial comparing tacrolimus extended-release/MMF, tacrolimus/MMF, and cyclosporine/MMF in de novo kidney transplant recipients. | 2014 | Transplantation | pmid:24521771 |
Kiiski V et al. | Long-term safety of topical pimecrolimus and topical tacrolimus in atopic blepharoconjunctivitis. | 2014 | JAMA Dermatol | pmid:24500107 |
Naganuma M et al. | [Clinical relevance of tacrolimus trough levels in outpatients with active ulcerative colitis]. | 2014 | Nihon Shokakibyo Gakkai Zasshi | pmid:24500317 |
Lapeyraque AL et al. | Conversion from twice- to once-daily tacrolimus in pediatric kidney recipients: a pharmacokinetic and bioequivalence study. | 2014 | Pediatr. Nephrol. | pmid:24435759 |
Højfeldt JW et al. | Bifunctional ligands allow deliberate extrinsic reprogramming of the glucocorticoid receptor. | 2014 | Mol. Endocrinol. | pmid:24422633 |
Saso S et al. | Uterine allotransplantation in a rabbit model using aorto-caval anastomosis: a long-term viability study. | 2014 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:25306223 |
Mekaj AY et al. | Application of topical pharmacological agents at the site of peripheral nerve injury and methods used for evaluating the success of the regenerative process. | 2014 | J Orthop Surg Res | pmid:25303779 |
Satoh S et al. | Pharmacokinetic and CYP3A5 pharmacogenetic differences between once- and twice-daily tacrolimus from the first dosing day to 1 year after renal transplantation. | 2014 | Pharmacogenomics | pmid:25303300 |
Müller GG et al. | Topical tacrolimus 0.03% as sole therapy in vernal keratoconjunctivitis: a randomized double-masked study. | 2014 | Eye Contact Lens | pmid:24418865 |
Meyer KC et al. | An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome. | 2014 | Eur. Respir. J. | pmid:25359357 |
Ahmed S et al. | Photocleavable dimerizer for the rapid reversal of molecular trap antagonists. | 2014 | J. Biol. Chem. | pmid:24421317 |
Souto-RodrÃguez R et al. | Differences in the incidence and clinical evolution of early neurotoxicity after liver transplantation based on tacrolimus formulation used in the immunosuppressive induction protocol. | 2014 | Transplant. Proc. | pmid:25420839 |
Al-Amri AM | Long-term follow-up of tacrolimus ointment for treatment of atopic keratoconjunctivitis. | 2014 | Am. J. Ophthalmol. | pmid:24439439 |
de la Fuente S et al. | Long-term survivors after pediatric liver transplatation are at increased risk for development of cardiovascular disease events: analysis of 30 cases. | 2014 | Transplant. Proc. | pmid:25420837 |
Kim JR et al. | 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol-fortified ginseng extract attenuates the development of atopic dermatitis-like symptoms in NC/Nga mice. | 2014 | J Ethnopharmacol | pmid:24269244 |
Tavira B et al. | Mitochondrial DNA haplogroups and risk of new-onset diabetes among tacrolimus-treated renal transplanted patients. | 2014 | Gene | pmid:24445060 |
Lin Y et al. | PERK activation preserves the viability and function of remyelinating oligodendrocytes in immune-mediated demyelinating diseases. | 2014 | Am. J. Pathol. | pmid:24269558 |
Barreiro C and MartÃnez-Castro M | Trends in the biosynthesis and production of the immunosuppressant tacrolimus (FK506). | 2014 | Appl. Microbiol. Biotechnol. | pmid:24272367 |
Masson P et al. | Belatacept for kidney transplant recipients. | 2014 | Cochrane Database Syst Rev | pmid:25416857 |
Xu W et al. | Toward immunosuppressive effects on liver transplantation in rat model: tacrolimus loaded poly(ethylene glycol)-poly(D,L-lactide) nanoparticle with longer survival time. | 2014 | Int J Pharm | pmid:24172796 |
Salehi-Najafabadi Z et al. | The gamma-butyrolactone receptors BulR1 and BulR2 of Streptomyces tsukubaensis: tacrolimus (FK506) and butyrolactone synthetases production control. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24562179 |
Xue W et al. | Effects of tacrolimus and cyclosporine treatment on metabolic syndrome and cardiovascular risk factors after renal transplantation: a meta-analysis. | 2014 | Chin. Med. J. | pmid:24931259 |
Gomez-Moyano E et al. | Periorbital granuloma annulare successfully treated with tacrolimus 0.1% ointment. | 2014 | Int. J. Dermatol. | pmid:23432464 |
Lalić J et al. | Immunosuppressive medication adherence in kidney transplant patients. | 2014 | Med Princ Pract | pmid:24923773 |
Gijsen VM et al. | P450 oxidoreductase *28 (POR*28) and tacrolimus disposition in pediatric kidney transplant recipients--a pilot study. | 2014 | Ther Drug Monit | pmid:24089076 |
Koren G and Rieder M | Measuring oral bioavailability of tacrolimus. | 2014 | Pediatr Transplant | pmid:25250966 |
Chen Z et al. | Mutations adjacent to the end of transmembrane helices 6 and 7 independently affect drug efflux capacity of yeast ABC transporter Pdr5p. | 2014 | Biochim. Biophys. Acta | pmid:24333836 |
Ueda K et al. | Early corticosteroid withdrawal in the real world: a long-term analysis of kidney transplant recipients from the Mycophenolic Acid Observational Renal Transplant Registry. | 2014 | Ann. Transplant. | pmid:24535029 |
Nasu R et al. | Favorable outcomes of tacrolimus compared with cyclosporine A for GVHD prophylaxis in HSCT for standard-risk hematological diseases. | 2014 | Ann. Hematol. | pmid:24590535 |
Kujawski S et al. | Calcineurin regulates coordinated outgrowth of zebrafish regenerating fins. | 2014 | Dev. Cell | pmid:24561038 |
Mujtaba MA et al. | Conversion from tacrolimus to belatacept to prevent the progression of chronic kidney disease in pancreas transplantation: case report of two patients. | 2014 | Am. J. Transplant. | pmid:25179306 |
Rahman Z et al. | Determination of tacrolimus crystalline fraction in the commercial immediate release amorphous solid dispersion products by a standardized X-ray powder diffraction method with chemometrics. | 2014 | Int J Pharm | pmid:25173870 |
Jia JJ et al. | ''Minimizing tacrolimus'' strategy and long-term survival after liver transplantation. | 2014 | World J. Gastroenterol. | pmid:25170223 |
Hao JC et al. | Effect of low-dose tacrolimus with mycophenolate mofetil on renal function following liver transplantation. | 2014 | World J. Gastroenterol. | pmid:25170222 |
Vattemi G et al. | Polymyositis in solid organ transplant recipients receiving tacrolimus. | 2014 | J. Neurol. Sci. | pmid:25130930 |
Görzer I et al. | Plasma DNA levels of Torque teno virus and immunosuppression after lung transplantation. | 2014 | J. Heart Lung Transplant. | pmid:24559947 |
Barnieh L et al. | The cost of kidney transplant over time. | 2014 | Prog Transplant | pmid:25193726 |
Calo S et al. | Antifungal drug resistance evoked via RNAi-dependent epimutations. | 2014 | Nature | pmid:25079329 |
Guy S et al. | Successful treatment of acute severe graft-versus-host-disease in a pancreas-after-kidney transplant recipient: case report. | 2014 | Transplant. Proc. | pmid:25179161 |
Yuan C et al. | A simple and robust LC-MS/MS method for measuring sirolimus and everolimus in whole blood. | 2014 | Bioanalysis | pmid:25077621 |
Aulagnon F et al. | Diarrhea after kidney transplantation: a new look at a frequent symptom. | 2014 | Transplantation | pmid:25073040 |
Beermann KJ et al. | Tacrolimus dose requirements in African-American and Caucasian kidney transplant recipients on mycophenolate and prednisone. | 2014 | Clin Transplant | pmid:24754564 |
Zwiech R | [The early C4d urinary excretion and long-term kidney graft survival in patients treated with tacrolimus and mycophenolate mophetil]. | 2014 | Pol. Merkur. Lekarski | pmid:24779215 |
Matia I et al. | Immunosuppressive protocol with delayed use of low-dose tacrolimus after aortic transplantation suppresses donor-specific anti-MHC class I and class II antibody production in rats. | 2014 | Ann. Transplant. | pmid:24815872 |
Harada N et al. | [Follow-up study on patients with vernal keratoconjunctivitis undergoing topical 0.1% tacrolimus treatment]. | 2014 | Nippon Ganka Gakkai Zasshi | pmid:24864437 |
Denfield SW | Oxidative and other stresses following pediatric heart transplantation. | 2014 | Pediatr Transplant | pmid:25250969 |
Izumi Y et al. | Safety of tacrolimus treatment during pregnancy and lactation in systemic lupus erythematosus: a report of two patients. | 2014 | Tohoku J. Exp. Med. | pmid:25175032 |
Piao SG et al. | Combined treatment of tacrolimus and everolimus increases oxidative stress by pharmacological interactions. | 2014 | Transplantation | pmid:24825522 |
Personett HA et al. | Impact of molecular adsorbent recirculating system therapy on tacrolimus elimination: a case report. | 2014 | Transplant. Proc. | pmid:25017243 |
Gujadhur A et al. | CMV sinusitis in a HIV-negative renal transplant recipient. | 2014 | Transplantation | pmid:24827770 |
Anderson JS et al. | Statistical allosteric coupling to the active site indole ring flip equilibria in the FK506-binding domain. | 2014 | Biophys. Chem. | pmid:25016286 |
Navas-López VM et al. | Oral tacrolimus for pediatric steroid-resistant ulcerative colitis. | 2014 | J Crohns Colitis | pmid:23582736 |
van Gelder T et al. | Pharmacogenetics and immunosuppressive drugs in solid organ transplantation. | 2014 | Nat Rev Nephrol | pmid:25247332 |
Tapirdamaz Ö et al. | Genetic variance in ABCB1 and CYP3A5 does not contribute toward the development of chronic kidney disease after liver transplantation. | 2014 | Pharmacogenet. Genomics | pmid:25014506 |
Helmschrott M et al. | Superior rejection profile during the first 24 months after heart transplantation under tacrolimus as baseline immunosuppressive regimen. | 2014 | Drug Des Devel Ther | pmid:25246772 |
Matta C et al. | Ser/Thr-phosphoprotein phosphatases in chondrogenesis: neglected components of a two-player game. | 2014 | Cell. Signal. | pmid:25007994 |
Matsuda Y et al. | Once-daily oral administration of cyclosporine in a lung transplant patient with a history of renal toxicity of calcineurin inhibitors. | 2014 | Interact Cardiovasc Thorac Surg | pmid:24659549 |
Hara H et al. | Hematopoietic chimerism following allotransplantation of the spleen, splenocytes or kidney in pigs. | 2014 | Transpl. Immunol. | pmid:25245436 |
Lunde I et al. | The influence of CYP3A, PPARA, and POR genetic variants on the pharmacokinetics of tacrolimus and cyclosporine in renal transplant recipients. | 2014 | Eur. J. Clin. Pharmacol. | pmid:24658827 |
Picchianti-Diamanti A et al. | P-glycoprotein and drug resistance in systemic autoimmune diseases. | 2014 | Int J Mol Sci | pmid:24658440 |
Andrade-Sierra J et al. | Early steroid withdrawal in a renal transplant cohort treated with tacrolimus, mycophenolate mofetil and basiliximab. | 2014 | Nefrologia | pmid:24658197 |
Webster P et al. | Tacrolimus is an effective treatment for lupus nephritis in pregnancy. | 2014 | Lupus | pmid:24928830 |
Wolfram D et al. | Insights from computational modeling in inflammation and acute rejection in limb transplantation. | 2014 | PLoS ONE | pmid:24926998 |
Zhao X et al. | [A retrospective cohort study regarding the effect of sirolimus-based immunosuppression protocol on the long-term survival of hepatocellular carcinoma patients after liver transplantation]. | 2014 | Zhonghua Wai Ke Za Zhi | pmid:24924566 |
Saito E et al. | Efficacy of salvage therapy and its effect on operative outcomes in patients with ulcerative colitis. | 2014 | Digestion | pmid:24458114 |
Song L et al. | Effects of ASKP1240 combined with tacrolimus or mycophenolate mofetil on renal allograft survival in Cynomolgus monkeys. | 2014 | Transplantation | pmid:24992357 |
Carbajo-Lozoya J et al. | Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir. | 2014 | Virus Res. | pmid:24566223 |
Rotter D et al. | Calcineurin and its regulator, RCAN1, confer time-of-day changes in susceptibility of the heart to ischemia/reperfusion. | 2014 | J. Mol. Cell. Cardiol. | pmid:24838101 |
Ren Y et al. | Tolerogenic dendritic cells modified by tacrolimus suppress CD4(+) T-cell proliferation and inhibit collagen-induced arthritis in mice. | 2014 | Int. Immunopharmacol. | pmid:24836681 |
Li H et al. | A promising approach of overcoming the intrinsic resistance of Candida krusei to fluconazole (FLC)--combining tacrolimus with FLC. | 2014 | FEMS Yeast Res. | pmid:24830342 |
Wang YB et al. | In vitro and in vivo performance of dry powder inhalation formulations: comparison of particles prepared by thin film freezing and micronization. | 2014 | AAPS PharmSciTech | pmid:24824172 |
Oda K et al. | In vitro experimental system for evaluating inhibitory effect of investigational drugs on P-glycoprotein-mediated transcellular transport of tacrolimus (FK506). | 2014 | Biopharm Drug Dispos | pmid:24822242 |
Wang Z et al. | Influence of TLR4 rs1927907 locus polymorphisms on tacrolimus pharmacokinetics in the early stage after liver transplantation. | 2014 | Eur. J. Clin. Pharmacol. | pmid:24820765 |
Welzl K et al. | Effect of different immunosuppressive drugs on immune cells from young and old healthy persons. | 2014 | Gerontology | pmid:24434865 |
Yang LM et al. | Experimental research on end-to-side anastomosis of peripheral nerves and effect of FK506 on end-to-side anastomosis. | 2014 | Bratisl Lek Listy | pmid:25573729 |
Taimur S et al. | Donor T-cell chimerism and early post-transplant cytomegalovirus viremia in patients treated with myeloablative allogeneic hematopoietic stem cell transplant. | 2014 | Transpl Infect Dis | pmid:24251680 |
Stewart JI et al. | Reverse halo sign on chest imaging in a renal transplant recipient. | 2014 | Transpl Infect Dis | pmid:24289813 |
Colom H et al. | Pharmacokinetic modeling of enterohepatic circulation of mycophenolic acid in renal transplant recipients. | 2014 | Kidney Int. | pmid:24402086 |
Muduma G et al. | A UK analysis of the cost of switching renal transplant patients from an immediate-release to a prolonged-release formulation of tacrolimus based on differences in trough concentration variability. | 2014 | J Med Econ | pmid:24754700 |
Shihab FS et al. | Tacrolimus exposure in the real world: an analysis from the Mycophenolic acid Observational REnal transplant study. | 2014 | Clin Transplant | pmid:24754603 |
Taube D et al. | Generic tacrolimus in solid organ transplantation. | 2014 | Clin Transplant | pmid:24750309 |
Bloch J et al. | Donor ABCB1 genetic polymorphisms influence epithelial-to-mesenchyme transition in tacrolimus-treated kidney recipients. | 2014 | Pharmacogenomics | pmid:25521359 |
Nacif LS et al. | An analysis of tacrolimus-related complications in the first 30 days after liver transplantation. | 2014 | Clinics (Sao Paulo) | pmid:25518032 |
Varghese J et al. | Tacrolimus-related adverse effects in liver transplant recipients: its association with trough concentrations. | 2014 | Indian J Gastroenterol | pmid:24740447 |
Kawaguch K et al. | Successful treatment with allogenic hematopoietic stem cell transplantation of a severe congenital neutropenia patient harboring a novel ELANE mutation. | 2014 | Rinsho Ketsueki | pmid:25501410 |
Cvetkovic TP et al. | Gender differences in oxidative and nitrosative stress parameters in kidney transplant patients on tacrolimus-based immunosuppression. | 2014 | Int Urol Nephrol | pmid:24101297 |
Hodzic E et al. | Posterior reversible encephalopathy syndrome (PRES) as a complication of immunosuppressive therapy in renal transplantation in children. | 2014 | Med Arh | pmid:25195358 |
Nishimoto K et al. | [Case of organizing pneumonia associated with sweet's syndrome]. | 2014 | Arerugi | pmid:25163580 |
Hässig A et al. | Association of BK viremia with human leukocyte antigen mismatches and acute rejection, but not with type of calcineurin inhibitor. | 2014 | Transpl Infect Dis | pmid:24134704 |
Elens L et al. | Clinical implementation of pharmacogenetics in kidney transplantation: calcineurin inhibitors in the starting blocks. | 2014 | Br J Clin Pharmacol | pmid:24118098 |
Manousou P et al. | Reduced fibrosis in recurrent HCV with tacrolimus, azathioprine and steroids versus tacrolimus: randomised trial long term outcomes. | 2014 | Gut | pmid:24131637 |
Langers P et al. | Limited sampling model for advanced mycophenolic acid therapeutic drug monitoring after liver transplantation. | 2014 | Ther Drug Monit | pmid:24081208 |
da Cunha Filho RR et al. | "Angular" plasma cell cheilitis. | 2014 | Dermatol. Online J. | pmid:24656273 |