tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Ileus D045823 3 associated lipids
Rectal Diseases D012002 1 associated lipids
Angiolymphoid Hyperplasia with Eosinophilia D000796 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Chen YH et al. [Prevention of diltiazem in tacrolimus-induced nephrotoxicity: experiment with rats]. 2007 Zhonghua Yi Xue Za Zhi pmid:18001539
Jin J et al. Impact of multidrug resistance 1 gene polymorphism on tacrolimus dose and concentration-to-dose ratio in Chinese liver transplantation recipients. 2005 Zhonghua Yi Xue Yi Chuan Xue Za Zhi pmid:16331555
Xie H et al. [Effect of FK506 eye-drop combined with keratoplasty on recurrent Mooren's ulcer]. 2002 Zhonghua Yan Ke Za Zhi pmid:11955293
Chen J et al. [The study of FK506 eye drops preventing and treating immune rejection on limbal allograft transplantation]. 2003 Zhonghua Yan Ke Za Zhi pmid:14766087
Xiang DM et al. [The observation of tacrolimus eye drops preventing the early immunological rejection after penetrating keratoplasty for fungal keratitis]. 2017 Zhonghua Yan Ke Za Zhi pmid:28412805
Sun YJ et al. [Systematic review of penetrating keratoplasty rejection treated by immunosuppressants]. 2010 Zhonghua Yan Ke Za Zhi pmid:21211228
Shi WY et al. [Implantation of FK506 drug delivery system into the anterior chamber for inhibiting corneal rejection in high risk rabbit corneal allograft]. 2006 Zhonghua Yan Ke Za Zhi pmid:16762204
Fei WL et al. [The pharmacokinetics of FK506 and its nanoparticles in aqueous humor of rabbits]. 2006 Zhonghua Yan Ke Za Zhi pmid:16762205
Lü L et al. [Experimental studies on the effect of the immunosuppressant FK-506 on penetrating keratoplasty rejection model in rats]. 1999 Zhonghua Yan Ke Za Zhi pmid:11835769
Lü L and Zhang W [Immunopathologic studies on the effects of immunosuppressant FK 506 on penetrating keratoplasty rejection model in rat]. 1998 Zhonghua Yan Ke Za Zhi pmid:11877144