tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Ileus D045823 3 associated lipids
Rectal Diseases D012002 1 associated lipids
Angiolymphoid Hyperplasia with Eosinophilia D000796 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

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Authors Title Published Journal PubMed Link
Abu Zaid M et al. Plasma biomarkers of risk for death in a multicenter phase 3 trial with uniform transplant characteristics post-allogeneic HCT. 2017 Blood pmid:27827824
Huh KH et al. De novo low-dose sirolimus versus mycophenolate mofetil in combination with extended-release tacrolimus in kidney transplant recipients: a multicentre, open-label, randomized, controlled, non-inferiority trial. 2017 Nephrol. Dial. Transplant. pmid:28810721
Choi SW et al. Vorinostat plus tacrolimus/methotrexate to prevent GVHD after myeloablative conditioning, unrelated donor HCT. 2017 Blood pmid:28784598
Kurzawski M et al. Analysis of common polymorphisms within NR1I2 and NR1I3 genes and tacrolimus dose-adjusted concentration in stable kidney transplant recipients. 2017 Pharmacogenet. Genomics pmid:28777242
Willerth SM Localized Tacrolimus Delivery Repairs the Damaged Central Nervous System. 2017 EBioMedicine pmid:29195745
Saito R et al. Two cases of eczematous drug eruption caused by oral tacrolimus administration. 2017 Contact Derm. pmid:28703346
Martial LC et al. Dried Blood Spot Sampling for Tacrolimus and Mycophenolic Acid in Children: Analytical and Clinical Validation. 2017 Ther Drug Monit pmid:28700522
Shahid S et al. Chronic hepatitis in the transplant patient. 2017 Br J Hosp Med (Lond) pmid:28692371
Lee JE et al. A Case of Rheumatoid Vasculitis Involving Hepatic Artery in Early Rheumatoid Arthritis. 2017 J. Korean Med. Sci. pmid:28581281
Riva N et al. Pharmacoepidemiology of tacrolimus in pediatric liver transplantation. 2017 Pediatr Transplant pmid:28574195
Wu H et al. Novel self-assembled tacrolimus nanoparticles cross-linking thermosensitive hydrogels for local rheumatoid arthritis therapy. 2017 Colloids Surf B Biointerfaces pmid:27736727
Damon C et al. Predictive Modeling of Tacrolimus Dose Requirement Based on High-Throughput Genetic Screening. 2017 Am. J. Transplant. pmid:27597269
Donati M et al. Resolution of Benign and Malignant Sebaceous Neoplasms, in a Renal Transplant Patient Treated With Everolimus. 2017 Exp Clin Transplant pmid:25924010
Kim YJ et al. Two cases of hydroa vacciniforme-like lymphoproliferative disease controlled by anti-inflammatory agents. 2017 Photodermatol Photoimmunol Photomed pmid:28543883
Zong YP et al. Effects of CYP3A5 polymorphisms on tacrolimus pharmacokinetics in pediatric kidney transplantation: a systematic review and meta-analysis of observational studies. 2017 World J Pediatr pmid:28540692
Seo SR et al. Disrupted Skin Barrier is Associated with Burning Sensation after Topical Tacrolimus Application in Atopic Dermatitis. 2017 Acta Derm. Venereol. pmid:28512670
Costa JS et al. Polyomavirus Nephropathy: Ten-Year Experience. 2017 Transplant. Proc. pmid:28457399
Egeland EJ et al. High Tacrolimus Clearance Is a Risk Factor for Acute Rejection in the Early Phase After Renal Transplantation. 2017 Transplantation pmid:28452920
Chiasson VL et al. Regulatory T-Cell Augmentation or Interleukin-17 Inhibition Prevents Calcineurin Inhibitor-Induced Hypertension in Mice. 2017 Hypertension pmid:28584011
Shoda W et al. Calcineurin inhibitors block sodium-chloride cotransporter dephosphorylation in response to high potassium intake. 2017 Kidney Int. pmid:28341239
Cakir U et al. Role of Everolimus on Cardiac Functions in Kidney Transplant Recipients. 2017 Transplant. Proc. pmid:28340820
Hettiarachchi PVKS et al. Comparison of topical tacrolimus and clobetasol in the management of symptomatic oral lichen planus: A double-blinded, randomized clinical trial in Sri Lanka. 2017 J Investig Clin Dent pmid:27633647
Ciftci HS et al. Influence of Proton Pump Inhibitors on Mycophenolic Acid Pharmacokinetics in Patients With Renal Transplantation and the Relationship With Cytochrome 2C19 Gene Polymorphism. 2017 Transplant. Proc. pmid:28340819
Rodrigues N et al. Serum Magnesium and Related Factors in Long-Term Renal Transplant Recipients: An Observational Study. 2017 Transplant. Proc. pmid:28457398
Mashayekhi S et al. The treatment of vulval lichen sclerosus in prepubertal girls: a critically appraised topic. 2017 Br. J. Dermatol. pmid:28244087
Guttman-Yassky E et al. Molecular signatures order the potency of topically applied anti-inflammatory drugs in patients with atopic dermatitis. 2017 J. Allergy Clin. Immunol. pmid:28238742
Takagi K et al. Syndrome of Inappropriate Antidiuretic Hormone Secretion Following Liver Transplantation. 2017 Acta Med. Okayama pmid:28238015
Rebora A Tacrolimus and oral lichen planus: the question remains. 2017 J Eur Acad Dermatol Venereol pmid:27324047
Kanai T et al. Adequate tacrolimus concentration for myasthenia gravis treatment. 2017 Eur. J. Neurol. pmid:28102047
Sarier M et al. HPV type 45-positive condyloma acuminata of the bladder in a renal transplant recipient. 2017 Transpl Infect Dis pmid:28100036
Fan B et al. Prograf produces more benefits for CYP3A5 low expression patients in early stage after kidney transplantation. 2017 Biomed. Pharmacother. pmid:28157649
Hanchanale P et al. Nocardia liver abscess post liver transplantation-A rare presentation. 2017 Transpl Infect Dis pmid:28150374
Størset E et al. The CYP3A biomarker 4β-hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation. 2017 Br J Clin Pharmacol pmid:28146606
Hashemizadeh Z et al. Observational Study of Associations between Voriconazole Therapeutic Drug Monitoring, Toxicity, and Outcome in Liver Transplant Patients. 2017 Antimicrob. Agents Chemother. pmid:28923870
Juvvadi PR et al. Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach. 2017 Virulence pmid:27325145
Shimizu K Development of New Liposome Targeting Strategies for Application of Disease Therapies. 2017 Yakugaku Zasshi pmid:28049894
Cukor D et al. A Pilot Randomized Controlled Trial to Promote Immunosuppressant Adherence in Adult Kidney Transplant Recipients. 2017 Nephron pmid:28049201
Calvo PL et al. Donor CYP3A5 genotype influences tacrolimus disposition on the first day after paediatric liver transplantation. 2017 Br J Clin Pharmacol pmid:28044353
Maneechote C et al. Roles of mitochondrial dynamics modulators in cardiac ischaemia/reperfusion injury. 2017 J. Cell. Mol. Med. pmid:28941171
Baskiran A et al. Pregnancy After Liver Transplantation: Risks and Outcomes. 2017 Transplant. Proc. pmid:28923640
Shi G et al. Variation of CD4CD25Foxp3 Regulatory T Cells and Th17 Cells in the Peripheral Blood of Human Liver Allograft Patients With Long-term Survival. 2017 Transplant. Proc. pmid:28923634
Weininger U et al. Dynamics of Aromatic Side Chains in the Active Site of FKBP12. 2017 Biochemistry pmid:27936610
Hosoi K et al. Prolonged tacrolimus for pediatric gastrointestinal disorder: Double-edged sword? 2017 Pediatr Int pmid:27935231
Alloway RR et al. Bioequivalence between innovator and generic tacrolimus in liver and kidney transplant recipients: A randomized, crossover clinical trial. 2017 PLoS Med. pmid:29135993
Parrow NL and Fleming RE Releasing the FKBP12 brake on hepcidin. 2017 Blood pmid:29122771
Kalt DA Tacrolimus: A Review of Laboratory Detection Methods and Indications for Use. 2017 Lab Med pmid:29096030
Gonzalez-Andrades M et al. Sterile Corneal Infiltrates Secondary to Psoriasis Exacerbations: Topical Tacrolimus as an Alternative Treatment Option. 2017 Eye Contact Lens pmid:26222098
Maldonado AQ et al. Prevalence of CYP3A5 Genomic Variances and Their Impact on Tacrolimus Dosing Requirements among Kidney Transplant Recipients in Eastern North Carolina. 2017 Pharmacotherapy pmid:28605053
Esquirol A et al. Single-agent GvHD prophylaxis with tacrolimus after post-transplant high-dose cyclophosphamide is a valid option for haploidentical transplantation in adults with hematological malignancies. 2017 Bone Marrow Transplant. pmid:28604667
Pietrosi G and Chinnici C Report on Liver Cell Transplantation Using Human Fetal Liver Cells. 2017 Methods Mol. Biol. pmid:27830561