| MeSH term | MeSH ID | Detail |
|---|---|---|
| Polymyositis | D017285 | 1 associated lipids |
| Scorpion Stings | D065008 | 1 associated lipids |
| Rotavirus Infections | D012400 | 1 associated lipids |
| Netherton Syndrome | D056770 | 1 associated lipids |
| Hepatic Veno-Occlusive Disease | D006504 | 1 associated lipids |
| West Nile Fever | D014901 | 1 associated lipids |
| Hypoalbuminemia | D034141 | 1 associated lipids |
| Arm Injuries | D001134 | 1 associated lipids |
| Intussusception | D007443 | 1 associated lipids |
| Thrombotic Microangiopathies | D057049 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kawano K et al. | FK506 reduces oxidative hepatic injury following cold ischemic preservation and transplantation. | 1996 | Transplant. Proc. | pmid:8658938 |
| Ishikawa M et al. | Acetaminophen absorption test as a useful indicator of small intestinal rejection in rats. | 1996 | Transplant. Proc. | pmid:8658911 |
| Hayakawa K et al. | Maintenance of unresponsiveness by short-term pulse therapy with FK 506 in rat transplantation. | 1996 | Transplant. Proc. | pmid:8658904 |
| Kawabe A et al. | Anti-adhesion (anti-ICAM-1 and anti-LFA-1) therapy in a rat pancreas transplantation model. | 1996 | Transplant. Proc. | pmid:8658893 |
| Kakefuda T et al. | Detection of nitrosylhemoglobin in liver allograft in rats by using near-infrared spectroscopy. | 1996 | Transplant. Proc. | pmid:8658885 |
| Park KM et al. | Bone loss after orthotopic liver transplantation: FK 506 versus cyclosporine. | 1996 | Transplant. Proc. | pmid:8658863 |
| Kokado Y et al. | Hypertension in renal transplant recipients and its effect on long-term renal allograft survival. | 1996 | Transplant. Proc. | pmid:8658802 |
| Zou XM et al. | Immunosuppressive effect of FK506 on orthotopic liver and small bowel xenotransplantation (xenoOLTx and SBTx). | 1996 | Transplant. Proc. | pmid:8658729 |
| Takeda M et al. | Pretreatment with splenectomy and FK506 in xeno-lung transplantation. | 1996 | Transplant. Proc. | pmid:8658728 |
| Sakimoto H et al. | Administration of tacrolimus (FK506) in hamster-to-rat pancreas xenotransplantation. | 1996 | Transplant. Proc. | pmid:8658727 |
| Kawauchi M et al. | Which are the target vessels of xeno- and allo-lung rejection?--a primate single lung transplantation study. | 1996 | Transplant. Proc. | pmid:8658719 |
| Yoshida Y et al. | Effect of lipoprostaglandin E1 in concordant xenografts. | 1996 | Transplant. Proc. | pmid:8658716 |
| Ogawa N et al. | Suppressive effects of combination therapy with mizoribine and FK 506 on the development of accelerated coronary artery disease and myocardial rejection after heart transplantation. | 1996 | Transplant. Proc. | pmid:8658710 |
| Yagura K et al. | Pharmacokinetic characteristics of two types of liposomal FK 506. | 1996 | Transplant. Proc. | pmid:8658708 |
| Yuzawa K et al. | Topical immunosuppression in skin grafting with FK 506 ointment. | 1996 | Transplant. Proc. | pmid:8658707 |
| Tojimbara T et al. | Cyclosporine and tacrolimus both suppress activation of Kupffer cells in vitro. | 1996 | Transplant. Proc. | pmid:8658704 |
| Watanabe K et al. | Immunosuppressive effect of bactobolamine in rat liver allotransplantation. | 1996 | Transplant. Proc. | pmid:8658697 |
| Degawa H et al. | Blocking of ICAM-1 and LFA-1 in rat liver transplantation. | 1996 | Transplant. Proc. | pmid:8658695 |
| Sugito K et al. | A comparative study of clinicopathologic characteristics of renal allografts under cyclosporine and FK506 immunosuppression. | 1996 | Transplant. Proc. | pmid:8658683 |
| Tanabe K et al. | Diabetes mellitus after renal transplantation under FK 506 (tacrolimus) as primary immunosuppression. | 1996 | Transplant. Proc. | pmid:8658670 |
| Nishimura Y et al. | Whole organ vascularized thymus allografting effectively modulates cardiac rejection. | 1996 | Transplant. Proc. | pmid:8658660 |
| Shinozuka N et al. | Correlation between simplified immunocompetence assay and clinical graft states in kidney or liver transplant recipients. | 1996 | Transplant. Proc. | pmid:8658649 |
| Harihara Y et al. | Effects of interferon alpha/beta on cardiac allografts. | 1996 | Transplant. Proc. | pmid:8658645 |
| Hisatomi A et al. | Effect of Prograf (FK506) on spermatogenesis in rats. | 1996 | Toxicology | pmid:8658548 |
| Pockley AG et al. | Effect of cyclosporin A, FK506 and rapamycin on proliferation and soluble IL-2 receptor release from mitogenically stimulated rat spleen cells. | 1995 | Biochem. Soc. Trans. | pmid:8654800 |
| Muraoka K et al. | Immunosuppressant FK506 induces interleukin-6 production through the activation of transcription factor nuclear factor (NF)-kappa(B). Implications for FK506 nephropathy. | 1996 | J. Clin. Invest. | pmid:8647935 |
| Colombani PM et al. | Liver transplantation in infants younger than 1 year of age. | 1996 | Ann. Surg. | pmid:8645039 |
| Morozumi K et al. | Diagnosis of chronic rejection using peritubular and glomerular capillary lesions. | 1996 | Transplant. Proc. | pmid:8644331 |
| Singh N et al. | Recurrent hepatitis C virus hepatitis in liver transplant recipients receiving tacrolimus: association with rejection and increased immunosuppression after transplantation. | 1996 | Surgery | pmid:8644012 |
| Kinoshita I et al. | Myoblast transplantation in monkeys: control of immune response by FK506. | 1996 | J. Neuropathol. Exp. Neurol. | pmid:8642394 |
| Ohtomo Y et al. | C-peptide stimulates rat renal tubular Na+, K(+)-ATPase activity in synergism with neuropeptide Y. | 1996 | Diabetologia | pmid:8635672 |
| Yoshimura N et al. | A case report of pregnancy in renal transplant recipient treated with FK506 (tacrolimus). | 1996 | Transplantation | pmid:8633388 |
| Kashu Y et al. | The effect of combination splenectomy and low-dose FK506 therapy on graft survival after liver allograft transplantation in rats. | 1996 | Transplantation | pmid:8633382 |
| Sun S et al. | Effect of tacrolimus on hemodynamics and absorption of experimental small intestinal transplants. | 1996 | Transplantation | pmid:8633368 |
| Schuetz EG et al. | Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. | 1996 | Mol. Pharmacol. | pmid:8632764 |
| Bierer BE | Mechanisms of action of immunosuppressive agents: cyclosporin A, FK506, and rapamycin. | 1995 | Proc. Assoc. Am. Physicians | pmid:8630742 |
| DiGiuseppe JA et al. | Tacrolimus-related posttransplant lymphoproliferative disorder presenting as autoimmune hemolytic anemia. | 1996 | Arch. Pathol. Lab. Med. | pmid:8629906 |
| Systemic tacrolimus (FK 506) is effective for the treatment of psoriasis in a double-blind, placebo-controlled study. The European FK 506 Multicentre Psoriasis Study Group. | 1996 | Arch Dermatol | pmid:8629845 | |
| Millis JM et al. | Tacrolimus for primary treatment of steroid-resistant hepatic allograft rejection. | 1996 | Transplantation | pmid:8629298 |
| Eberhard OK et al. | How best to use tacrolimus (FK506) for treatment of steroid- and OKT3-resistant rejection after renal transplantation. | 1996 | Transplantation | pmid:8629294 |
| Dragovich PS et al. | Structure-based design of novel, urea-containing FKBP12 inhibitors. | 1996 | J. Med. Chem. | pmid:8627611 |
| Zhang BW et al. | T cell responses in calcineurin A alpha-deficient mice. | 1996 | J. Exp. Med. | pmid:8627154 |
| Fehr T et al. | Antascomicins A, B, C, D and E. Novel FKBP12 binding compounds from a Micromonospora strain. | 1996 | J. Antibiot. | pmid:8626235 |
| Asfar S et al. | Small bowel transplantation. A life-saving option for selected patients with intestinal failure. | 1996 | Dig. Dis. Sci. | pmid:8625758 |
| Appignani BA et al. | Neuroimaging findings in patients on immunosuppressive therapy: experience with tacrolimus toxicity. | 1996 | AJR Am J Roentgenol | pmid:8623651 |
| Woodle ES et al. | Role of protocol biopsies in the treatment of refractory renal allograft rejection with FK 506. | 1996 | Transplant. Proc. | pmid:8623495 |
| Alloway RR et al. | Conversion from cyclosporine to tacrolimus in kidney, kidney/pancreas, and pancreas alone transplant recipients: the Memphis experience. | 1996 | Transplant. Proc. | pmid:8623494 |
| Birk PE et al. | Preliminary experience with FK 506 in pediatric renal transplant recipients: a single-center report. | 1996 | Transplant. Proc. | pmid:8623493 |
| Stratta RJ et al. | FK 506 induction and rescue therapy in pancreas transplant recipients. | 1996 | Transplant. Proc. | pmid:8623492 |
| McKenna BA et al. | Tacrolimus (FK 506): a whole blood assay as measured on the Abbott IMx analyzer. | 1996 | Transplant. Proc. | pmid:8623491 |
| Troppmann C et al. | Perioperative immunosuppression as a critical determinant of early outcome after discordant xenoislet transplantation: a comparative study. | 1996 | Transplant. Proc. | pmid:8623487 |
| Butt TR et al. | Molecular basis of immunosuppressive drug action: regulation of steroid receptor-mediated transcription by FK 506. | 1996 | Transplant. Proc. | pmid:8623486 |
| Klintmalm GB | Clinical use of FK 506 in liver transplantation. | 1996 | Transplant. Proc. | pmid:8623484 |
| D'Silva M et al. | Immunosuppressive effect of brequinar on rat cardiac allograft survival in combination with leflunomide or FK 506. | 1996 | Transplant. Proc. | pmid:8623476 |
| Ciancio G et al. | Human donor bone marrow cells can enhance hyporeactivity in renal transplantation using maintenance FK 506 and OKT3 induction therapy. | 1996 | Transplant. Proc. | pmid:8623473 |
| Pirenne J et al. | Bone marrow augmentation of kidney allografts can cause graft-versus-host disease in immunosuppressed recipients. | 1996 | Transplant. Proc. | pmid:8623472 |
| D'Silva M et al. | Immunosuppressive effect of RS-61443 on rat cardiac allograft survival in combination with leflunomide or FK 506. | 1996 | Transplant. Proc. | pmid:8623467 |
| Kyo M et al. | Results with histological diagnosis in kidney transplant rejections treated with 15-deoxyspergualin. | 1996 | Transplant. Proc. | pmid:8623457 |
| Ketel BL et al. | Tacrolimus-based vs cyclosporine-based immunotherapy in combined kidney-pancreas transplantation. | 1996 | Transplant. Proc. | pmid:8623453 |
| Andrews WS et al. | Comparison of cyclosporine- vs tacrolimus-based immunosuppression in pediatric liver transplantation. | 1996 | Transplant. Proc. | pmid:8623452 |
| Harrison DM et al. | Reduction in hospital stay after liver transplantation. | 1996 | Transplant. Proc. | pmid:8623451 |
| Pirenne J et al. | Addition of the colon to small bowel grafts causes lethal graft-versus-host disease in FK 506-treated pigs. | 1996 | Transplant. Proc. | pmid:8623447 |
| Sung RS et al. | Survival of human islet xenografts irradiated with ultraviolet B in diabetic rats. | 1996 | Transplant. Proc. | pmid:8623427 |
| Horimoto H et al. | Hepatocyte xenotransplantation for Nagase's analbuminemic rats: the effect of FK506. | 1996 | Transplant. Proc. | pmid:8623421 |
| Andereggen E et al. | Immunohistological study of islet xenograft rejection in immunosuppressed recipients. | 1996 | Transplant. Proc. | pmid:8623420 |
| Takeda M et al. | Methotrexate in rescue therapy for xenotransplanted lungs in primates. | 1996 | Transplant. Proc. | pmid:8623402 |
| Fukushima N et al. | Histological findings in heart grafts after orthotopic pig to baboon cardiac transplantation. | 1996 | Transplant. Proc. | pmid:8623400 |
| Pan F et al. | Effect of tacrolimus and splenectomy on engraftment and GVHD after bone marrow xenotransplantation in the reciprocal hamster to rat animal models. | 1996 | Transplant. Proc. | pmid:8623373 |
| Wakizaka Y et al. | Xenotransplantation of hamster liver into Gunn rats reserves congenital hyperbilirubinemia. | 1996 | Transplant. Proc. | pmid:8623372 |
| Valdivia LA et al. | Prolonged survival of hearts obtained from chimeric donors in a mouse to rat xenotransplant model. | 1996 | Transplant. Proc. | pmid:8623371 |
| Namii Y et al. | Tetrahydropyranyladriamycin with FK 506 combination therapy for hamster-to-rat-concordant xenotransplantation. | 1996 | Transplant. Proc. | pmid:8623358 |
| Ye Q et al. | Functional analysis of hamster kidney xenografts in the rat: possible functional incompatibility and adaptation of hamster kidney grafts in a xenogenic rat environment. | 1996 | Transplant. Proc. | pmid:8623350 |
| Tanaka M et al. | Tacrolimus (FK 506)-dependent tolerance after liver and heart xenotransplantation: inhibition of humoral response and acceptance of donor organs. | 1996 | Transplant. Proc. | pmid:8623341 |
| Smit JA et al. | Induction of primate TH2 lymphokines to suppress TH1 cells. | 1996 | Transplant. Proc. | pmid:8623334 |
| Jin MB et al. | Protective effect of FK 506 on hepatic energy metabolism in warm ischemic canine livers induced by total hepatic vascular exclusion. | 1996 | Transplant. Proc. | pmid:8623243 |
| Nakai T et al. | Immunosuppressive mechanism and immune tolerance of FK 506 in rat small bowel transplantation. | 1996 | Transplant. Proc. | pmid:8623237 |
| Takada S et al. | HGF prevents tacrolimus (FK 506)-induced nephrotoxicity in SHR rats. | 1996 | Transplant. Proc. | pmid:8623236 |
| Morozumi K et al. | A comparative study of morphological characteristics of renal injuries of tacrolimus (FK506) and cyclosporin (CyA) in renal allografts: are the morphologic characteristics of FK506 and CyA nephrotoxicity similar? | 1996 | Transplant. Proc. | pmid:8623232 |
| Ko S et al. | Different immunosuppressive effects of liposomal FK506 in liver and kidney transplantation. | 1996 | Transplant. Proc. | pmid:8623229 |
| Nakajima H and Oka T | The inhibition of T-cell-receptor-induced Fas ligand upregulation by cyclosporine and FK 506. | 1996 | Transplant. Proc. | pmid:8623224 |
| Tomikawa S et al. | Immunosuppressive effects of bactobolamine in vitro and in vivo. | 1996 | Transplant. Proc. | pmid:8623223 |
| Hashikura Y et al. | Immunosuppressant switching between cyclosporine and tacrolimus after liver transplantation. | 1996 | Transplant. Proc. | pmid:8623218 |
| Regazzi MB et al. | Interaction between FK 506 and diltiazem in an animal model. | 1996 | Transplant. Proc. | pmid:8623215 |
| Washburn WK et al. | Tacrolimus rescue therapy for renal allograft rejection refractory to cyclosporine-based immunosuppression. | 1996 | Transplant. Proc. | pmid:8623214 |
| Millis JM et al. | Treatment of steroid-resistant rejection with tacrolimus prior to OKT3 in liver transplant recipients. | 1996 | Transplant. Proc. | pmid:8623213 |
| Sher LS et al. | Tacrolimus (FK 506) for rescue of chronic rejection following orthotopic liver transplantation. | 1996 | Transplant. Proc. | pmid:8623212 |
| Bechstein WO et al. | Tacrolimus (FK 506) therapy is associated with a significant reduction in immunosuppressive treatment failures following primary liver transplantation. | 1996 | Transplant. Proc. | pmid:8623211 |
| Loss M et al. | Glucose and lipid metabolism in liver transplant patients under long-term tacrolimus (FK 506) monotherapy. | 1996 | Transplant. Proc. | pmid:8623210 |
| Satomura K et al. | Pharmacokinetics of FK 506 in living-related liver transplantation. | 1996 | Transplant. Proc. | pmid:8623209 |
| Pham SM et al. | Tacrolimus (FK 506) in clinical cardiac transplantation: a five-year experience. | 1996 | Transplant. Proc. | pmid:8623208 |
| Ciancio G et al. | Current advantage of FK 506 in cadaveric kidney transplantation. | 1996 | Transplant. Proc. | pmid:8623207 |
| Koprak S et al. | Depletion of the mature CD4+8- thymocyte subset by FK506 analogs correlates with their immunosuppressive and calcineurin inhibitory activities. | 1996 | Transplantation | pmid:8623162 |
| Roth D et al. | A prospective study of hepatitis C virus infection in renal allograft recipients. | 1996 | Transplantation | pmid:8623154 |
| Kiang D et al. | Cloning the gene encoding Schistosoma mansoni p50, an immunophilin. | 1996 | Gene | pmid:8621074 |
| Panyi G et al. | Immunosuppressors inhibit voltage-gated potassium channels in human peripheral blood lymphocytes. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8619842 |
| Li W and Handschumacher RE | Regulation of the nuclear factor of activated T cells in stably transfected Jurkat cell clones. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8619834 |
| Rappersberger K et al. | Clearing of psoriasis by a novel immunosuppressive macrolide. | 1996 | J. Invest. Dermatol. | pmid:8618008 |
| Igarashi O et al. | B7-1 synergizes with interleukin-12 in interleukin-2 receptor alpha expression by mouse T helper 1 clones. | 1996 | Eur. J. Immunol. | pmid:8617295 |
| pmid:8615615 | ||||
| Pham SM et al. | A prospective trial of tacrolimus (FK 506) in clinical heart transplantation: intermediate-term results. | 1996 | J. Thorac. Cardiovasc. Surg. | pmid:8614136 |