| MeSH term | MeSH ID | Detail |
|---|---|---|
| Digestive System Fistula | D016154 | 1 associated lipids |
| Crigler-Najjar Syndrome | D003414 | 1 associated lipids |
| Leukoplakia, Oral | D007972 | 1 associated lipids |
| Peroneal Neuropathies | D020427 | 1 associated lipids |
| Poxviridae Infections | D011213 | 1 associated lipids |
| Kaposi Varicelliform Eruption | D007617 | 1 associated lipids |
| Lacerations | D022125 | 1 associated lipids |
| Megacolon, Toxic | D008532 | 1 associated lipids |
| Hepatitis, Autoimmune | D019693 | 1 associated lipids |
| Moyamoya Disease | D009072 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Berney T et al. | Islet of Langerhans allogeneic transplantation at the University of Geneva in the steroid free era in islet after kidney and simultaneous islet-kidney transplantations. | 2004 | Transplant. Proc. | pmid:15194390 |
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| Watanabe K et al. | Fate of long-surviving allografts in tolerant recipients induced by fractionated lymphoid irradiation, donor bone marrow cell infusion, and FK 506 after retransplantation in dogs. | 1993 | Transplant. Proc. | pmid:7679813 |
| Strasser S et al. | The effect of FK 506 on canine pancreatic islet cell function in beagle dogs. | 1991 | Transplant. Proc. | pmid:1703709 |
| Ryu S and Yasunami Y | Prevention of immune rejection in rat islet allografts by continuous SC administration of FK 506 using a mini-osmotic pump. | 1991 | Transplant. Proc. | pmid:1703710 |
| Thomson AW | Interspecies comparison of the immunosuppressive efficacy and safety of FK 506. | 1990 | Transplant. Proc. | pmid:1689883 |
| Latorre A et al. | Clinical management of renal transplant patients with hepatitis C virus infection treated with cyclosporine or tacrolimus. | 2002 | Transplant. Proc. | pmid:11959186 |
| Urbizu JM et al. | Immunosuppression using tacrolimus/mycophenolate versus neoral/mycophenolate following kidney transplantation: a single-center experience. | 2002 | Transplant. Proc. | pmid:11959197 |
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| Shapiro R et al. | Outcome after steroid withdrawal in renal transplant patients receiving tacrolimus-based immunosuppression. | 1998 | Transplant. Proc. | pmid:9636557 |
| González E et al. | Everolimus represents an advance in immunosuppression for patients who have developed cancer after renal transplantation. | 2009 Jul-Aug | Transplant. Proc. | pmid:19715911 |
| Elmer DS et al. | Metabolic effects of FK 506 (tacrolimus) versus cyclosporine in portally drained pancreas allografts. | 1998 | Transplant. Proc. | pmid:9532159 |
| Burke GW et al. | Tacrolimus-related microangiopathy in kidney and simultaneous pancreas-kidney recipients: evidence of endothelin and cytokine involvement. | 1998 | Transplant. Proc. | pmid:9532223 |
| Rajnoch J et al. | Regulators of angiogenesis in renal ischemia/reperfusion injury in normotensive and hypertensive rats: effect of tacrolimus. | 2005 Jan-Feb | Transplant. Proc. | pmid:15808641 |
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| Mueller AR et al. | Influence of immunosuppression on patient outcome after liver transplantation. | 1998 | Transplant. Proc. | pmid:9636608 |
| Bilodeau JF et al. | Evaluation of tolerability and ability to increase immunosuppression in renal transplant patients converted from mycophenolate mofetil to enteric-coated mycophenolate sodium. | 2009 | Transplant. Proc. | pmid:19917367 |
| Le Dinh H et al. | Evolution of native kidney function after pancreas transplantation alone. | 2012 | Transplant. Proc. | pmid:23146535 |
| McAlister VC et al. | Cost of liver transplantation using tacrolimus. | 1998 | Transplant. Proc. | pmid:9636611 |
| Kawauchi M et al. | Cardiac xenotransplantation from pig to Japanese monkey with splenectomy, tacrolims, filtration plasmapheresis, and nafamstat mesilate. | 1994 | Transplant. Proc. | pmid:7518105 |
| Ohtsuka S et al. | Effect of splenectomy on hamster-to-rat pancreas xenotransplantation. | 1994 | Transplant. Proc. | pmid:7518109 |
| Platz KP et al. | OKT3 vs FK 506 rescue management of acute steroid-resistant and chronic rejection. | 1995 | Transplant. Proc. | pmid:7533357 |
| Porayko MK et al. | Comparing nephrotoxicity of FK 506 and cyclosporine regimens after liver transplantation: preliminary results from US Multicenter trial. U.S. Multicenter Liver Study Group. | 1995 | Transplant. Proc. | pmid:7533358 |
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| Andersson J et al. | The effects of FK 506 on cytokine production are dependent on the mode of cell activation. | 1991 | Transplant. Proc. | pmid:1721311 |
| Wang SC et al. | FK 506, rapamycin, and cyclosporine: effects on IL-4 and IL-10 mRNA levels in a T-helper 2 cell line. | 1991 | Transplant. Proc. | pmid:1721312 |
| Imai K et al. | Pancreaticoduodenal allotransplantation with the use of FK 506, cyclosporine, and triple-regimen immunosuppression. | 1990 | Transplant. Proc. | pmid:1697117 |
| Iga C et al. | Prolonged survival of small intestinal allograft in the rat with cyclosporine A, FK 506, and 15-deoxyspergualin. | 1990 | Transplant. Proc. | pmid:1697118 |
| Masuda S et al. | Initial dosage adjustment for oral administration of tacrolimus using the intestinal MDR1 level in living-donor liver transplant recipients. | 2005 | Transplant. Proc. | pmid:15919446 |
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| Ogino S et al. | Conversion from tacrolimus to cyclosporine microemulsion therapy in liver transplant recipients. | 2004 | Transplant. Proc. | pmid:15041357 |
| Kawano K et al. | Protective effect of FK 506 on hepatic injury following cold ischemic preservation and transplantation: influence on hepatic microcirculation. | 1995 | Transplant. Proc. | pmid:7533410 |
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| Odoul F et al. | Massive ingestion of tacrolimus in a young liver transplant patient. | 1998 | Transplant. Proc. | pmid:9865375 |
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| Gelens MA et al. | Do blood pressure and arterial wall properties change after conversion from cyclosporine to tacrolimus? | 2005 | Transplant. Proc. | pmid:15919498 |
| Cronin DC et al. | Tacrolimus therapy for refractory renal allograft rejection: experience with steroid withdrawal. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123010 |
| Zhu Y et al. | Prolongation of canine renal allograft survival by combining tacrolimus with antimetabolic agents. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123011 |
| Rossi G et al. | Results of orthotopic liver-small bowel transplantation in the pig using different immunosuppressive regimens. | 1996 | Transplant. Proc. | pmid:8907932 |
| Platz KP et al. | Immunosuppressive power and limitations of FK 506 for prevention and treatment of graft-vs-host disease after small bowel transplantation. | 1996 | Transplant. Proc. | pmid:8907933 |
| Lorho R et al. | Improved liver function and decreased hepatitis C viral load after tacrolimus was replaced by cyclosporine. | 2005 Jul-Aug | Transplant. Proc. | pmid:16182838 |
| Feitoza CQ et al. | A role for HO-1 in renal function impairment in animals subjected to ischemic and reperfusion injury and treated with immunosuppressive drugs. | 2007 | Transplant. Proc. | pmid:17362747 |
| Morphopathological findings of renal allografts under FK 506 therapy. Japanese FK 506 Study Group. | 1994 | Transplant. Proc. | pmid:7520614 | |
| Imanishi M et al. | Induction of tolerance by intrathymic injection of donor bone marrow cells in the rat: simultaneous heart and skin allograft model. | 1994 | Transplant. Proc. | pmid:7520615 |
| Morris SM et al. | Disruption of renal function and gene expression by FK 506 and cyclosporine. | 1991 | Transplant. Proc. | pmid:1721375 |
| Mange KC and Bloom RD | Rates of acute rejection by recipient race and type of calcineurin inhibitor with mycophenolate mofetil. | 2002 | Transplant. Proc. | pmid:12493393 |
| Lagodziński Z et al. | Effect of FK 506 on B-cell responses. | 1991 | Transplant. Proc. | pmid:1703359 |
| Domenech N et al. | Neither acute rejection nor immunosuppressant drug therapy (cyclosporine or tacrolimus) correlates with expression of either CD40 or CD154 on peripheral blood cells among human cardiac transplant patients. | 2003 | Transplant. Proc. | pmid:12962873 |
| Wayman MR et al. | Two-year outcome in renal allograft recipients comparing neoral-led with tacrolimus-led therapy. | 2002 | Transplant. Proc. | pmid:12176526 |
| Kaufman DB et al. | Single-center experience of 60 consecutive simultaneous pancreas-kidney transplants using mycophenolate mofetil and tacrolimus as primary maintenance immunotherapy. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083261 |
| Nakamura Y et al. | Safety and efficacy of conversion from twice-daily tacrolimus (prograf) to once-daily prolonged-release tacrolimus (graceptor) in stable kidney transplant recipients. | 2012 | Transplant. Proc. | pmid:22310595 |
| Guo Z et al. | Leflunomide, a potential immunosuppressant for pancreatic islet transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123314 |
| Jiang Y et al. | Dyslipidemia in human kidney transplant recipients receiving cyclosporine and tacrolimus is associated with different expression of CD36 on peripheral blood monocytes. | 2011 | Transplant. Proc. | pmid:21693242 |
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| Chen YB et al. | Suitable calcineurin inhibitor concentrations for liver transplant recipients in the Chinese population. | 2011 | Transplant. Proc. | pmid:21693271 |
| Golling M et al. | Tacrolimus reduction improves glucose metabolism and insulin secretion after liver transplantation. | 1996 | Transplant. Proc. | pmid:8962234 |
| Platz KP et al. | Incidence and outcome of chronic rejection in CyA- and FK 506-treated patients. | 1996 | Transplant. Proc. | pmid:8962235 |
| Lauro A et al. | Rejection episodes and 3-year graft survival under sirolimus and tacrolimus treatment after adult intestinal transplantation. | 2007 | Transplant. Proc. | pmid:17580204 |
| Pirsch JD et al. | Pulmonary infiltrates and eosinophilia in an FK 506 liver transplant recipient. | 1991 | Transplant. Proc. | pmid:1721406 |
| Wada H et al. | Combination use of suboptimal doses of FK 506 and cyclosporine in canine lung transplantation. | 1992 | Transplant. Proc. | pmid:1379758 |
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| Cai X et al. | Low-dose of FK 506 and associated blood levels in allotransplantation of rat liver, heart, and skin. | 1992 | Transplant. Proc. | pmid:1379759 |
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