tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Denys-Drash Syndrome D030321 1 associated lipids
Hypophosphatemia D017674 1 associated lipids
Moyamoya Disease D009072 1 associated lipids
Latent Tuberculosis D055985 1 associated lipids
Leukoplakia D007971 1 associated lipids
Oculomotor Nerve Diseases D015840 1 associated lipids
Scorpion Stings D065008 1 associated lipids
Esophageal Perforation D004939 1 associated lipids
Mediastinitis D008480 2 associated lipids
Coproporphyria, Hereditary D046349 1 associated lipids
Ileus D045823 3 associated lipids
Rectal Diseases D012002 1 associated lipids
Angiolymphoid Hyperplasia with Eosinophilia D000796 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Bieber T et al. Efficacy and safety of methylprednisolone aceponate ointment 0.1% compared to tacrolimus 0.03% in children and adolescents with an acute flare of severe atopic dermatitis. 2007 Allergy pmid:17298428
Bergstrand H and Lundquist B Human basophil histamine release is differently affected by inhibitors of calmodulin, diacylglycerol kinase and peptidyl prolyl cis-trans isomerase in a secretagogue specific manner. 1992 Allergy pmid:1280915
Leonardi S et al. Efficacy and safety of tacrolimus ointment 0.03% treatment in a 1-month-old "red baby": a case report. 2006 Nov-Dec Allergy Asthma Proc pmid:17176789
Pacor ML et al. Tacrolimus ointment in nickel sulphate-induced steroid-resistant allergic contact dermatitis. 2006 Nov-Dec Allergy Asthma Proc pmid:17176790
Rico MJ and Lawrence I Tacrolimus ointment for the treatment of atopic dermatitis: clinical and pharmacologic effects. 2002 May-Jun Allergy Asthma Proc pmid:12125507
Szema AM Angioedema in a child with a liver transplant, intussusception, and normal c4 levels. 2010 Jul-Aug Allergy Asthma Proc pmid:20615276
Kay AB Immunosuppressive agents in chronic severe asthma. 1994 May-Jun Allergy Proc pmid:7523242
Wilhelmi E et al. Organotypic brain-slice cultures from adult rats: approaches for a prolonged culture time. 2002 May-Jun Altern Lab Anim pmid:12106005
Mcauliffe EP Is tacrolimus the best therapy for atopic dermatitis? 2003 Am Fam Physician pmid:12751651
Lane JE and Johnson J Persistent penile patch. 2008 Am Fam Physician pmid:19007056
Russell JJ Topical tacrolimus: a new therapy for atopic dermatitis. 2002 Am Fam Physician pmid:12469964
Berke R et al. Atopic dermatitis: an overview. 2012 Am Fam Physician pmid:22962911
Hitzeman N and Kinnevey C Topical Tacrolimus for Eczema. 2016 Am Fam Physician pmid:27929217
Baran DA et al. Calcineurin inhibitor-associated early renal insufficiency in cardiac transplant recipients: risk factors and strategies for prevention and treatment. 2004 Am J Cardiovasc Drugs pmid:14967063
Ramirez R et al. Posterior Reversible Encephalopathy Syndrome After Orthotopic Heart Transplantation: A Case Report. 2017 Am J Case Rep pmid:28465499
Kawamura H et al. Rapid Induction Therapy with Oral Tacrolimus in Elderly Patients with Refractory Ulcerative Colitis Can Easily Lead to Elevated Tacrolimus Concentrations in Blood: A Report of 5 Cases. 2017 Am J Case Rep pmid:28411286
Udomkarnjananun S et al. An Unusual Manifestation of Calcineurin Inhibitor-Induced Pain Syndrome in Kidney Transplantation: A Case Report and Literature Review. 2018 Am J Case Rep pmid:29654227
Iskedjian M et al. Topical calcineurin inhibitors in the treatment of atopic dermatitis: a meta-analysis of current evidence. 2004 Am J Clin Dermatol pmid:15301573
Wellington K and Noble S Pimecrolimus: a review of its use in atopic dermatitis. 2004 Am J Clin Dermatol pmid:15663345
Reitamo S et al. Topical noncorticosteroid immunomodulation in the treatment of atopic dermatitis. 2002 Am J Clin Dermatol pmid:12113647