tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Denys-Drash Syndrome D030321 1 associated lipids
Hypophosphatemia D017674 1 associated lipids
Moyamoya Disease D009072 1 associated lipids
Latent Tuberculosis D055985 1 associated lipids
Leukoplakia D007971 1 associated lipids
Oculomotor Nerve Diseases D015840 1 associated lipids
Scorpion Stings D065008 1 associated lipids
Esophageal Perforation D004939 1 associated lipids
Mediastinitis D008480 2 associated lipids
Coproporphyria, Hereditary D046349 1 associated lipids
Ileus D045823 3 associated lipids
Rectal Diseases D012002 1 associated lipids
Angiolymphoid Hyperplasia with Eosinophilia D000796 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Breuer K et al. Safety and efficacy of topical calcineurin inhibitors in the treatment of childhood atopic dermatitis. 2005 Am J Clin Dermatol pmid:15799678
Gupta AK and Versteeg SG Topical Treatment of Facial Seborrheic Dermatitis: A Systematic Review. 2017 Am J Clin Dermatol pmid:27804089
Yang LP and Curran MP Spotlight on topical pimecrolimus in pediatric atopic dermatitis. 2010 Am J Clin Dermatol pmid:20509720
Cheer SM and Plosker GL Tacrolimus ointment. A review of its therapeutic potential as a topical therapy in atopic dermatitis. 2001 Am J Clin Dermatol pmid:11770393
Ozden MG et al. Topical pimecrolimus 1% cream for resistant seborrheic dermatitis of the face: an open-label study. 2010 Am J Clin Dermatol pmid:20000875
Patel TS et al. Cancer concerns with topical immunomodulators in atopic dermatitis: overview of data and recommendations to clinicians. 2007 Am J Clin Dermatol pmid:17645374
Mertens JS et al. Morphea and Eosinophilic Fasciitis: An Update. 2017 Am J Clin Dermatol pmid:28303481
Frankel HC and Qureshi AA Comparative effectiveness of topical calcineurin inhibitors in adult patients with atopic dermatitis. 2012 Am J Clin Dermatol pmid:22263704
Iskedjian M et al. Topical calcineurin inhibitors in the treatment of atopic dermatitis: a meta-analysis of current evidence. 2004 Am J Clin Dermatol pmid:15301573
Kroft EB et al. Efficacy of topical tacrolimus 0.1% in active plaque morphea: randomized, double-blind, emollient-controlled pilot study. 2009 Am J Clin Dermatol pmid:19354332
Siegfried EC et al. Topical calcineurin inhibitors and lymphoma risk: evidence update with implications for daily practice. 2013 Am J Clin Dermatol pmid:23703374
Tjioe M et al. Topical macrolide immunomodulators: a role in the treatment of vitiligo? 2006 Am J Clin Dermatol pmid:16489839
Valdivielso-Ramos M et al. Significant improvement in extensive lichen sclerosus with tacrolimus ointment and PUVA. 2008 Am J Clin Dermatol pmid:18429647
Wellington K and Noble S Pimecrolimus: a review of its use in atopic dermatitis. 2004 Am J Clin Dermatol pmid:15663345
Cook BA and Warshaw EM Role of topical calcineurin inhibitors in the treatment of seborrheic dermatitis: a review of pathophysiology, safety, and efficacy. 2009 Am J Clin Dermatol pmid:19222250
Reitamo S et al. Topical noncorticosteroid immunomodulation in the treatment of atopic dermatitis. 2002 Am J Clin Dermatol pmid:12113647
Wellington K and Jarvis B Spotlight on topical pimecrolimus in atopic dermatitis. 2002 Am J Clin Dermatol pmid:12113651
Lübbe J et al. Safety, efficacy, and dosage of 1% pimecrolimus cream for the treatment of atopic dermatitis in daily practice. 2006 Am J Clin Dermatol pmid:16605292
Ellis CN et al. Cost effectiveness of management of mild-to-moderate atopic dermatitis with 1% pimecrolimus cream in children and adolescents 2-17 years of age. 2006 Am J Clin Dermatol pmid:16605293
Kasper RC et al. Anetoderma arising in cutaneous B-cell lymphoproliferative disease. 2001 Am J Dermatopathol pmid:11285407