tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Inappropriate ADH Syndrome D007177 4 associated lipids
Hearing Loss, Noise-Induced D006317 4 associated lipids
Hydronephrosis D006869 4 associated lipids
Papillomavirus Infections D030361 4 associated lipids
Confusion D003221 4 associated lipids
Hyperparathyroidism, Secondary D006962 4 associated lipids
Bone Diseases D001847 4 associated lipids
Hepatitis B, Chronic D019694 4 associated lipids
Foot Ulcer D016523 4 associated lipids
Neoplasms, Second Primary D016609 4 associated lipids
Eczema D004485 4 associated lipids
Osteonecrosis D010020 5 associated lipids
Anemia, Hemolytic, Autoimmune D000744 5 associated lipids
Enterobacteriaceae Infections D004756 5 associated lipids
Femur Head Necrosis D005271 5 associated lipids
Hematoma D006406 5 associated lipids
Vasculitis, Leukocytoclastic, Cutaneous D018366 5 associated lipids
Erythema Nodosum D004893 5 associated lipids
Respiration Disorders D012120 5 associated lipids
Skin Diseases, Vesiculobullous D012872 5 associated lipids
Mouth Diseases D009059 5 associated lipids
Postoperative Complications D011183 5 associated lipids
Hand Dermatoses D006229 5 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Sclerosis D012598 5 associated lipids
Mastocytosis D008415 5 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Tinea D014005 5 associated lipids
Myasthenia Gravis D009157 5 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Liver Failure D017093 5 associated lipids
Osteomalacia D010018 5 associated lipids
Neoplasm Recurrence, Local D009364 5 associated lipids
Trypanosomiasis D014352 5 associated lipids
Alopecia Areata D000506 6 associated lipids
Gliosis D005911 6 associated lipids
Bronchiolitis D001988 6 associated lipids
Infection D007239 6 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Pancytopenia D010198 6 associated lipids
Sarcoma, Kaposi D012514 6 associated lipids
Graves Disease D006111 6 associated lipids
Anemia, Aplastic D000741 6 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Angioedema D000799 6 associated lipids
Gynecomastia D006177 6 associated lipids
Thrombophlebitis D013924 6 associated lipids
Anemia, Iron-Deficiency D018798 6 associated lipids
Heart Injuries D006335 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Shapiro R Tacrolimus in pediatric renal transplantation: a review. 1998 Pediatr Transplant pmid:10084728
Atkison P et al. Small bowel transplantation in children. 1997 Pediatr Transplant pmid:10084770
Webber SA 15 years of pediatric heart transplantation at the University of Pittsburgh: lessons learned and future prospects. 1997 Pediatr Transplant pmid:10084782
Yura H et al. Synthesis and pharmacokinetics of a novel macromolecular prodrug of Tacrolimus (FK506), FK506-dextran conjugate. 1999 J Control Release pmid:10084872
Trimbur GM et al. Cloning, sequencing, and nucleolar targeting of the basal-body-binding nucleolar protein BN46/51. 1999 J. Cell. Sci. pmid:10085251
Liang J et al. Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution. 1999 Acta Crystallogr. D Biol. Crystallogr. pmid:10089303
Crabtree GR Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT. 1999 Cell pmid:10089876
Kimura T et al. N-glycosylation is involved in the sensitivity of Saccharomyces cerevisiae to HM-1 killer toxin secreted from Hansenula mrakii IFO 0895. 1999 Appl. Microbiol. Biotechnol. pmid:10091323
Nakahama H et al. Effect of FK 506 in the treatment of autoimmune glomerulonephritis in Brown Norway rats. 1999 Nephron pmid:10095178
Kenyon NS et al. Islet transplantation: present and future perspectives. 1998 Diabetes Metab Rev pmid:10095999