Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Soda Y et al. | Suppressed endothelin-1 production by FK506 and cyclosporin A in ischemia/reperfusion of rat small intestine. | 1999 | Surgery | pmid:9889794 |
Yoshioka K et al. | Post-transplant diabetes with anti-glutamic acid decarboxylase antibody during tacrolimus therapy. | 1998 | Diabetes Res. Clin. Pract. | pmid:9886744 |
Chen YW et al. | Ex vivo assessment of immunosuppression in undiluted whole blood from pigs dosed with tacrolimus (FK506). | 1999 | Clin. Immunol. | pmid:9884362 |
Solez K et al. | Histopathologic findings from 2-year protocol biopsies from a U.S. multicenter kidney transplant trial comparing tarolimus versus cyclosporine: a report of the FK506 Kidney Transplant Study Group. | 1998 | Transplantation | pmid:9884269 |
Fisher RA et al. | A prospective randomized trial of mycophenolate mofetil with neoral or tacrolimus after orthotopic liver transplantation. | 1998 | Transplantation | pmid:9884248 |
Harrison S et al. | Stimulation of airway sensory nerves by cyclosporin A and FK506 in guinea-pig isolated bronchus. | 1998 | Br. J. Pharmacol. | pmid:9884067 |
Herzberg GZ et al. | The effects of HLA mismatching and immunosuppressive therapy on early rejection outcome in pediatric heart transplant recipients. | 1998 | J. Heart Lung Transplant. | pmid:9883760 |
Trajković V et al. | Cyclosporin A inhibits activation of inducible nitric oxide synthase in C6 glioma cell line. | 1999 | Brain Res. | pmid:9878697 |
He G et al. | Modified surgical model of paratopic small bowel transplantation in mice. | 1998 | J. Surg. Res. | pmid:9878312 |
Madsen JR et al. | Tacrolimus (FK506) increases neuronal expression of GAP-43 and improves functional recovery after spinal cord injury in rats. | 1998 | Exp. Neurol. | pmid:9878202 |