tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Orchitis D009920 1 associated lipids
Optic Neuritis D009902 1 associated lipids
Opportunistic Infections D009894 8 associated lipids
Oliguria D009846 2 associated lipids
Obesity D009765 29 associated lipids
Nocardia Infections D009617 6 associated lipids
Neutropenia D009503 15 associated lipids
Neuromyelitis Optica D009471 2 associated lipids
Neuromuscular Diseases D009468 10 associated lipids
Neurodermatitis D009450 1 associated lipids
Neuritis D009443 4 associated lipids
Nervous System Diseases D009422 37 associated lipids
Nerve Degeneration D009410 53 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Nephritis, Hereditary D009394 1 associated lipids
Nephritis D009393 19 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Neoplasm Recurrence, Local D009364 5 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Necrobiosis Lipoidica D009335 2 associated lipids
Nail Diseases D009260 2 associated lipids
Myxedema D009230 2 associated lipids
Myelitis D009187 1 associated lipids
Mycoses D009181 18 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Mycobacterium Infections D009164 7 associated lipids
Myasthenia Gravis D009157 5 associated lipids
Mutism D009155 1 associated lipids
Muscular Dystrophies D009136 10 associated lipids
Multiple Myeloma D009101 13 associated lipids
Moyamoya Disease D009072 1 associated lipids
Mouth Diseases D009059 5 associated lipids
Molluscum Contagiosum D008976 2 associated lipids
Mite Infestations D008924 1 associated lipids
Metaplasia D008679 7 associated lipids
Meningoencephalitis D008590 4 associated lipids
Meningococcal Infections D008589 3 associated lipids
Memory Disorders D008569 33 associated lipids
Melanoma D008545 69 associated lipids
Megacolon, Toxic D008532 1 associated lipids
Mediastinitis D008480 2 associated lipids
Mediastinal Emphysema D008478 1 associated lipids
Mediastinal Diseases D008477 1 associated lipids
Mastocytosis D008415 5 associated lipids
Malocclusion, Angle Class II D008312 1 associated lipids
Malacoplakia D008287 1 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Lymphomatoid Granulomatosis D008230 2 associated lipids
Lymphoma D008223 18 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Ong CS Tacrolimus ointment for atopic dermatitis. 1998 N. Engl. J. Med. pmid:9867560
Marone G Tacrolimus ointment for atopic dermatitis. 1998 N. Engl. J. Med. pmid:9867559
Onose J et al. Ca2+-ATPase inhibitor induces IL-4 and MCP-1 production in RBL-2H3 cells. 1998 Immunol. Lett. pmid:9865597
Reis A et al. Mycophenolate mofetil and FK506: two novel immunosuppressants in murine corneal transplantation. 1998 Transplant. Proc. pmid:9865380
Escartín A et al. Analysis of pig-MAP after small bowel transplantation in pigs. 1998 Transplant. Proc. pmid:9865377
Odoul F et al. Massive ingestion of tacrolimus in a young liver transplant patient. 1998 Transplant. Proc. pmid:9865375
Gerauer K et al. Long-term cardiac allograft survival in mice treated with malononitrilamide 715. 1998 Transplant. Proc. pmid:9865349
Yokoyama I et al. Immunosuppressant effect on Fas antigen expression and p53 of an experimental tumor. 1998 Transplant. Proc. pmid:9865346
Ahlmén J et al. Positive effects of tacrolimus in a case of CIDP. 1998 Transplant. Proc. pmid:9865344
Schorlemmer HU and Kurrle R Combination therapy of malononitrilamides and tacrolimus (FK 506) induced long-term xenograft survival. 1998 Transplant. Proc. pmid:9865337
Kilian K et al. FK-506 (tacrolimus) therapy for an unusual SLE-like disease. 1998 Transplant. Proc. pmid:9865322
Metcalfe SM et al. In vitro transcription and translation of the tumour suppressor protein P53: qualitative and quantitative effects of FK506 and rapamycin. 1998 Transplant. Proc. pmid:9865315
Schorlemmer HU et al. Long-term allograft survival and tolerance induction by the synergistic activity of malononitrilamides and tacrolimus. 1998 Transplant. Proc. pmid:9865312
Braun F et al. How to handle mycophenolate mofetil in combination with tacrolimus? 1998 Transplant. Proc. pmid:9865309
Daoud AJ et al. A comparison of the safety and efficacy of mycophenolate mofetil, prednisone and cyclosporine and mycophenolate mofetil, and prednisone and tacrolimus. 1998 Transplant. Proc. pmid:9865303
du Toit DF et al. Tacrolimus (FK506) monotherapy provides potent and significant suppression of allogeneic foetal rat pancreatic allograft rejection. 1998 Transplant. Proc. pmid:9865300
Fleck PR et al. Tacrolimus use in kidney-pancreas recipients is associated with less acute renal dysfunction than cyclosporine. 1998 Transplant. Proc. pmid:9865299
Brunet M et al. Therapeutic drug monitoring of tacrolimus in kidney transplantation: 9-month follow-up. 1998 Transplant. Proc. pmid:9865298
Moffatt SD et al. Comparative efficacy of liposomal FK506 with FK506. 1998 Transplant. Proc. pmid:9865297
Opelz G Evaluation of immunosuppressive induction regimens in renal transplantation. Collaborative Transplant Study. 1998 Transplant. Proc. pmid:9865286