tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Varela E | [Small bowel transplantation]. | 1995 | Acta Gastroenterol. Latinoam. | pmid:7544939 |
| Pirenne J | Contribution of large animal models to the development of clinical intestinal transplantation. | 1999 Apr-Jun | Acta Gastroenterol. Belg. | pmid:10427786 |
| Jamieson NV | Adult small intestinal transplantation in Europe. | 1999 Apr-Jun | Acta Gastroenterol. Belg. | pmid:10427790 |
| Bonaccorsi-Riani E et al. | Impact of steroid-avoidance immunosuppression on long-term outcome after liver transplantation for HCV cirrhosis: the need for well documented long-term follow-up. | 2012 | Acta Gastroenterol. Belg. | pmid:23402084 |
| Reding R et al. | Stepwise minimization of the immunosuppressive therapy in pediatric liver transplantation. A conceptual approach towards operational tolerance. | 2005 Jul-Sep | Acta Gastroenterol. Belg. | pmid:16268418 |
| Sato M et al. | FK506 inhibits phytohemagglutinin-, but not interferon-gamma-, induced HLA-DR antigen expression and accessory cell function on primary cultured human thyroid cells. | 1993 | Acta Endocrinol. | pmid:7509103 |
| Polastri L et al. | Secretory defects induced by immunosuppressive agents on human pancreatic beta-cells. | 2002 | Acta Diabetol | pmid:12486498 |
| Persić-Vojinović S et al. | Disseminated Hailey-Hailey disease treated with topical tacrolimus and oral erythromycin: Case report and review of the literature. | 2006 | Acta Dermatovenerol Croat | pmid:17311740 |
| Louvain D et al. | Lichen sclerosus in the oral mucosa: a rare form of presentation. | 2012 | Acta Dermatovenerol Croat | pmid:22507475 |
| Lipozencić J | Pimecrolimus--a safe and effective local immunomodulator in the treatment of inflammatory skin diseases. | 2005 | Acta Dermatovenerol Croat | pmid:15788149 |
| Pustisek N et al. | Tacrolimus ointment: a new therapy for atopic dermatitis--review of the literature. | 2002 | Acta Dermatovenerol Croat | pmid:12137728 |
| Jedlicková H et al. | Granuloma faciale successfully treated with topical tacrolimus: a case report. | 2008 | Acta Dermatovenerol Alp Pannonica Adriat | pmid:18454269 |
| Thaçi D and Salgo R | The topical calcineurin inhibitor pimecrolimus in atopic dermatitis: a safety update. | 2007 | Acta Dermatovenerol Alp Pannonica Adriat | pmid:17992459 |
| Vukićević J et al. | Unilateral multiple lichen striatus treated with tacrolimus ointment: a case report. | 2009 | Acta Dermatovenerol Alp Pannonica Adriat | pmid:19350187 |
| Pagliarello C and Paradisi A | Topical tacrolimus is useful for avoiding suction-blister epidermal grafting depigmentation in non-segmental vitiligo: a case report. | 2012 | Acta Derm. Venereol. | pmid:22101735 |
| Hamade Y et al. | Lichen planus in childhood showing various cutaneous features. | 2012 | Acta Derm. Venereol. | pmid:22101991 |
| Mandelin J et al. | Leg ulcers treated with topical tacrolimus in patients with rheumatoid arthritis. | 2010 | Acta Derm. Venereol. | pmid:21057750 |
| Nakamizo S et al. | Treatment of neuropathic itch possibly due to trigeminal trophic syndrome with 0.1% topical tacrolimus and gabapentin. | 2010 | Acta Derm. Venereol. | pmid:21057761 |
| Jensen JM et al. | Effects of pimecrolimus compared with triamcinolone acetonide cream on skin barrier structure in atopic dermatitis: a randomized, double-blind, right-left arm trial. | 2013 | Acta Derm. Venereol. | pmid:23571785 |
| Pagliarello C et al. | Topical tacrolimus and 50% zinc oxide paste for Hailey-Hailey disease: less is more. | 2012 | Acta Derm. Venereol. | pmid:22293917 |