tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Hypersensitivity D006967 22 associated lipids
Osteosarcoma D012516 50 associated lipids
Acne Vulgaris D000152 35 associated lipids
Urination Disorders D014555 9 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Anemia, Hemolytic D000743 4 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Vision Disorders D014786 10 associated lipids
Multiple Myeloma D009101 13 associated lipids
Osteochondrodysplasias D010009 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Zhou YN et al. Effect of amlodipine on the pharmacokinetics of tacrolimus in rats. 2013 Xenobiotica pmid:23312000
Ogawa K et al. A new approach to predicting human hepatic clearance of CYP3A4 substrates using monkey pharmacokinetic data. 2013 Xenobiotica pmid:23153054
Jeong H and Chiou WL Role of P-glycoprotein in the hepatic metabolism of tacrolimus. 2006 Xenobiotica pmid:16507509
Imamura R et al. ABO-incompatible kidney transplantation with anti-CD20 monoclonal antibodies, intravenous immunoglobulin and plasmapheresis without splenectomy: a case report. 2006 Xenotransplantation pmid:16623807
Song Z et al. Tacrolimus inhibits discordant islet xenograft rejection: a study in the pig-to-rat model. 2003 Xenotransplantation pmid:14617270
Balamurugan AN et al. Effect of various immunosuppressive monotherapies on survival and histopathology of monkey islet xenografts in rats. 2007 Xenotransplantation pmid:17669173
Miki T et al. Hamster-to-rat bone marrow xenotransplantation and humoral graft vs. host disease. 2001 Xenotransplantation pmid:11472629
Tachibana A et al. Repopulation of the immunosuppressed retrorsine-treated infant rat liver with human hepatocytes. 2013 Jul-Aug Xenotransplantation pmid:23683097
He QH et al. [The role of superantigen SEB-induced immunotolerance in the immune privileged site]. 2003 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:15132898
Bai YJ et al. [Regulatory function of tacrolimus and CsA on CD4/CD8 T lymphocyte subgroups and costimulators on them in allo-liver recipients]. 2008 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:18845086