tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Hypersensitivity D006967 22 associated lipids
Osteosarcoma D012516 50 associated lipids
Acne Vulgaris D000152 35 associated lipids
Urination Disorders D014555 9 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Anemia, Hemolytic D000743 4 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Vision Disorders D014786 10 associated lipids
Multiple Myeloma D009101 13 associated lipids
Osteochondrodysplasias D010009 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Breuer K et al. Safety and efficacy of topical calcineurin inhibitors in the treatment of childhood atopic dermatitis. 2005 Am J Clin Dermatol pmid:15799678
Gupta AK and Versteeg SG Topical Treatment of Facial Seborrheic Dermatitis: A Systematic Review. 2017 Am J Clin Dermatol pmid:27804089
Kalavala M and Dohil MA Calcineurin inhibitors in pediatric atopic dermatitis: a review of current evidence. 2011 Am J Clin Dermatol pmid:21067248
Cheer SM and Plosker GL Tacrolimus ointment. A review of its therapeutic potential as a topical therapy in atopic dermatitis. 2001 Am J Clin Dermatol pmid:11770393
Ozden MG et al. Topical pimecrolimus 1% cream for resistant seborrheic dermatitis of the face: an open-label study. 2010 Am J Clin Dermatol pmid:20000875
Patel TS et al. Cancer concerns with topical immunomodulators in atopic dermatitis: overview of data and recommendations to clinicians. 2007 Am J Clin Dermatol pmid:17645374
Mertens JS et al. Morphea and Eosinophilic Fasciitis: An Update. 2017 Am J Clin Dermatol pmid:28303481
Frankel HC and Qureshi AA Comparative effectiveness of topical calcineurin inhibitors in adult patients with atopic dermatitis. 2012 Am J Clin Dermatol pmid:22263704
Valdivielso-Ramos M et al. Significant improvement in extensive lichen sclerosus with tacrolimus ointment and PUVA. 2008 Am J Clin Dermatol pmid:18429647
Wellington K and Noble S Pimecrolimus: a review of its use in atopic dermatitis. 2004 Am J Clin Dermatol pmid:15663345
Ingram JR et al. Impact of topical calcineurin inhibitors on quality of life in patients with atopic dermatitis. 2009 Am J Clin Dermatol pmid:19489656
Lübbe J et al. Safety, efficacy, and dosage of 1% pimecrolimus cream for the treatment of atopic dermatitis in daily practice. 2006 Am J Clin Dermatol pmid:16605292
Ellis CN et al. Cost effectiveness of management of mild-to-moderate atopic dermatitis with 1% pimecrolimus cream in children and adolescents 2-17 years of age. 2006 Am J Clin Dermatol pmid:16605293
Wollina U The role of topical calcineurin inhibitors for skin diseases other than atopic dermatitis. 2007 Am J Clin Dermatol pmid:17492844
Ramirez R et al. Posterior Reversible Encephalopathy Syndrome After Orthotopic Heart Transplantation: A Case Report. 2017 Am J Case Rep pmid:28465499
Kawamura H et al. Rapid Induction Therapy with Oral Tacrolimus in Elderly Patients with Refractory Ulcerative Colitis Can Easily Lead to Elevated Tacrolimus Concentrations in Blood: A Report of 5 Cases. 2017 Am J Case Rep pmid:28411286
Udomkarnjananun S et al. An Unusual Manifestation of Calcineurin Inhibitor-Induced Pain Syndrome in Kidney Transplantation: A Case Report and Literature Review. 2018 Am J Case Rep pmid:29654227
Baran DA et al. Calcineurin inhibitor-associated early renal insufficiency in cardiac transplant recipients: risk factors and strategies for prevention and treatment. 2004 Am J Cardiovasc Drugs pmid:14967063
Mcauliffe EP Is tacrolimus the best therapy for atopic dermatitis? 2003 Am Fam Physician pmid:12751651
Lane JE and Johnson J Persistent penile patch. 2008 Am Fam Physician pmid:19007056