| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypersensitivity | D006967 | 22 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Urination Disorders | D014555 | 9 associated lipids |
| Arterial Occlusive Diseases | D001157 | 12 associated lipids |
| Anemia, Hemolytic | D000743 | 4 associated lipids |
| Leukemia, Erythroblastic, Acute | D004915 | 41 associated lipids |
| Vision Disorders | D014786 | 10 associated lipids |
| Multiple Myeloma | D009101 | 13 associated lipids |
| Osteochondrodysplasias | D010009 | 3 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Eckhoff DE et al. | Tacrolimus (FK506) and mycophenolate mofetil combination therapy versus tacrolimus in adult liver transplantation. | 1998 | Transplantation | pmid:9458011 |
| Gold BG | FK506 and the role of immunophilins in nerve regeneration. | 1997 | Mol. Neurobiol. | pmid:9457703 |
| Sikorski R and Peters R | Droplet discovery. | 1998 | Science | pmid:9454334 |
| Egner R et al. | Genetic separation of FK506 susceptibility and drug transport in the yeast Pdr5 ATP-binding cassette multidrug resistance transporter. | 1998 | Mol. Biol. Cell | pmid:9450972 |
| Lauerma AI et al. | Absorption of topical tacrolimus (FK506) in vitro through human skin: comparison with cyclosporin A. | 1997 | Skin Pharmacol. | pmid:9449161 |
| Fletcher L | Specific neuroimmunophilin ligands to treat neurodegenerative disease. | 1997 | Mol Med Today | pmid:9449119 |
| Alaiti S et al. | Tacrolimus (FK506) ointment for atopic dermatitis: a phase I study in adults and children. | 1998 | J. Am. Acad. Dermatol. | pmid:9448208 |
| Cavaillé-Coll MW and Elashoff MR | Commentary on a comparison of tacrolimus and cyclosporine for immunosuppression after cadaveric renal transplantation. | 1998 | Transplantation | pmid:9448161 |
| Ernst A et al. | Lung abcess complicating Legionella micdadei pneumonia in an adult liver transplant recipient: case report and review. | 1998 | Transplantation | pmid:9448158 |
| Mentzer RM et al. | Tacrolimus as a rescue immunosuppressant after heart and lung transplantation. The U.S. Multicenter FK506 Study Group. | 1998 | Transplantation | pmid:9448154 |
| McCune TR et al. | Effects of tacrolimus on hyperlipidemia after successful renal transplantation: a Southeastern Organ Procurement Foundation multicenter clinical study. | 1998 | Transplantation | pmid:9448150 |
| Rosen HR et al. | Significance of early aminotransferase elevation after liver transplantation. | 1998 | Transplantation | pmid:9448146 |
| Miyauchi T et al. | Effect of donor-specific splenocytes via portal vein and FK506 in rat small bowel transplantation. | 1998 | Transplantation | pmid:9448139 |
| Dumont FJ et al. | A tacrolimus-related immunosuppressant with reduced toxicity. | 1998 | Transplantation | pmid:9448138 |
| Peterson LB et al. | A tacrolimus-related immunosuppressant with biochemical properties distinct from those of tacrolimus. | 1998 | Transplantation | pmid:9448137 |
| Singh N et al. | Predictors and outcome of early- versus late-onset major bacterial infections in liver transplant recipients receiving tacrolimus (FK506) as primary immunosuppression. | 1997 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9447904 |
| Alak AM et al. | An HPLC/MS/MS assay for tacrolimus in patient blood samples. Correlation with results of an ELISA assay. | 1997 | J Pharm Biomed Anal | pmid:9447546 |
| [Transplantation medicine. Tacrolimus increases survival chances after organ transplantation. XVI International Congress of the Transplantation Society. 25-30 August 1996 Barcelona]. | 1996 | Dtsch. Med. Wochenschr. | pmid:9447224 | |
| Jin L et al. | Stimulating cell proliferation through the pharmacologic activation of c-kit. | 1998 | Blood | pmid:9446649 |
| McDiarmid SV | The use of tacrolimus in pediatric liver transplantation. | 1998 | J. Pediatr. Gastroenterol. Nutr. | pmid:9443127 |
| Garattini S | Are me-too drugs justified? | 1997 Nov-Dec | J. Nephrol. | pmid:9442441 |
| Rühlmann A and Nordheim A | Effects of the immunosuppressive drugs CsA and FK506 on intracellular signalling and gene regulation. | 1997 | Immunobiology | pmid:9442391 |
| Davis EC et al. | Identification of tropoelastin as a ligand for the 65-kD FK506-binding protein, FKBP65, in the secretory pathway. | 1998 | J. Cell Biol. | pmid:9442105 |
| Yokoyama I et al. | Fas antigen expression of hepatocytes and its modification by immunosuppressants. | 1997 | Dig. Dis. Sci. | pmid:9440622 |
| Furutani M et al. | Biochemical and genetic characterization of an FK506-sensitive peptidyl prolyl cis-trans isomerase from a thermophilic archaeon, Methanococcus thermolithotrophicus. | 1998 | J. Bacteriol. | pmid:9440528 |
| Garraffo R | [Clinical pharmacokinetics and therapeutic monitoring of tacrolimus]. | 1997 Jul-Aug | Therapie | pmid:9437890 |
| Billaud EM et al. | [Immunosuppression: a case of mucoviscidosis]. | 1997 Jul-Aug | Therapie | pmid:9437888 |
| Boucek MM et al. | The Registry of the International Society of Heart and Lung Transplantation: first official pediatric report--1997. | 1997 | J. Heart Lung Transplant. | pmid:9436131 |
| Ito E and Tanaka Y | Influences of immunosuppressive agents, FK506 and cyclosporin on systemic Candida albicans infection in mice. | 1997 | Mycopathologia | pmid:9433807 |
| Alessiani M et al. | [Flexibility of the surgical model of intestinal transplantation in swine]. | 1997 | Minerva Chir | pmid:9432575 |
| Paterson DL and Singh N | Interactions between tacrolimus and antimicrobial agents. | 1997 | Clin. Infect. Dis. | pmid:9431391 |
| Midtvedt K et al. | Successful pregnancies in a combined pancreas and renal allograft recipient and in a renal graft recipient on tacrolimus treatment. | 1997 | Nephrol. Dial. Transplant. | pmid:9430893 |
| Kitagaki K et al. | Facilitation of apoptosis by cyclosporins A and H, but not FK506 in mouse bronchial eosinophils. | 1997 | Eur. J. Pharmacol. | pmid:9430427 |
| DiMartini AF et al. | Neuropsychiatric side effects of FK506 vs. cyclosporine A. First-week postoperative findings. | 1997 Nov-Dec | Psychosomatics | pmid:9427854 |
| Yang J et al. | Small-molecule control of insulin and PDGF receptor signaling and the role of membrane attachment. | 1998 | Curr. Biol. | pmid:9427627 |
| Vu MD et al. | Tacrolimus (FK506) and sirolimus (rapamycin) in combination are not antagonistic but produce extended graft survival in cardiac transplantation in the rat. | 1997 | Transplantation | pmid:9422432 |
| Shihab FS et al. | Mechanism of fibrosis in experimental tacrolimus nephrotoxicity. | 1997 | Transplantation | pmid:9422427 |
| Stegall MD et al. | Prednisone withdrawal 14 days after liver transplantation with mycophenolate: a prospective trial of cyclosporine and tacrolimus. | 1997 | Transplantation | pmid:9422416 |
| Shield CF et al. | Assessment of health-related quality of life in kidney transplant patients receiving tacrolimus (FK506)-based versus cyclosporine-based immunosuppression. FK506 Kidney Transplant Study Group. | 1997 | Transplantation | pmid:9422413 |
| Stegall MD et al. | Mycophenolate mofetil decreases rejection in simultaneous pancreas-kidney transplantation when combined with tacrolimus or cyclosporine. | 1997 | Transplantation | pmid:9422404 |
| Spencer CM et al. | Tacrolimus. An update of its pharmacology and clinical efficacy in the management of organ transplantation. | 1997 | Drugs | pmid:9421697 |
| Nicoletti F et al. | Paradoxical antidiabetogenic effect of gamma-interferon in DP-BB rats. | 1998 | Diabetes | pmid:9421371 |
| Salm P et al. | High-performance liquid chromatography-tandem mass spectrometry as a reference for analysis of tacrolimus to assess two immunoassays in patients with liver and renal transplants. | 1997 | Ther Drug Monit | pmid:9421113 |
| Braun F et al. | Pitfalls in monitoring tacrolimus (FK 506). | 1997 | Ther Drug Monit | pmid:9421102 |
| Talbot D et al. | Alopecia as a consequence of tacrolimus therapy in renal transplantation? | 1997 | Transplantation | pmid:9415574 |
| Gruessner RW and Sharp HL | Living-related intestinal transplantation: first report of a standardized surgical technique. | 1997 | Transplantation | pmid:9415566 |
| Lang T et al. | Cholic acid synthesis is reduced in pediatric liver recipients during graft dysfunction due to ischemic injury and allograft rejection. | 1997 | Transplantation | pmid:9415561 |
| Gruessner RW et al. | Solitary pancreas transplantation for nonuremic patients with labile insulin-dependent diabetes mellitus. | 1997 | Transplantation | pmid:9415558 |
| Scantlebury VP et al. | Outcome of kidney transplantation in African-Americans using tacrolimus. | 1997 | Transplant. Proc. | pmid:9414906 |
| Weber M et al. | Decreased rejection episodes in African-American renal transplant recipients receiving mycophenolate mofetil/tacrolimus therapy. | 1997 | Transplant. Proc. | pmid:9414883 |