| MeSH term | MeSH ID | Detail |
|---|---|---|
| Eye Infections, Viral | D015828 | 1 associated lipids |
| Dysplastic Nevus Syndrome | D004416 | 1 associated lipids |
| Hypoplastic Left Heart Syndrome | D018636 | 1 associated lipids |
| Mite Infestations | D008924 | 1 associated lipids |
| Polyendocrinopathies, Autoimmune | D016884 | 1 associated lipids |
| Leukoplakia | D007971 | 1 associated lipids |
| Fasciitis, Necrotizing | D019115 | 1 associated lipids |
| Colitis, Collagenous | D046729 | 1 associated lipids |
| Malacoplakia | D008287 | 1 associated lipids |
| Myoclonic Cerebellar Dyssynergia | D002527 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Platz KP et al. | Causes of death following liver transplantation in FK 506- and cyclosporine-treated patients. | 1994 | Transplant. Proc. | pmid:7527952 |
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| Felldin M et al. | Rescue therapy with Tacrolimus (FK506) in renal transplant recipients--a multicenter analysis. | 1995 | Transplant. Proc. | pmid:8540032 |
| Kahan BD | Cyclosporine: the base for immunosuppressive therapy--present and future. | 1993 | Transplant. Proc. | pmid:7679819 |
| Bersztel A et al. | Deoxyspergualin is synergistic with cyclosporin A, but not with FK506 in a rat heart allograft transplantation model. | 1995 | Transplant. Proc. | pmid:8540095 |
| Tze WJ et al. | Prolongation of pig islet xenograft survival in rats by local immunosuppression with FK 506. | 1994 | Transplant. Proc. | pmid:7513471 |
| Ferraresso M et al. | Conversion from cyclosporine to tacrolimus for refractory acute rejection in pediatric kidney transplant recipients: a single-center experience. | 2001 Nov-Dec | Transplant. Proc. | pmid:11750525 |
| Starzl TE | FK 506 versus cyclosporine. | 1993 | Transplant. Proc. | pmid:7679820 |
| Fukuzaki T et al. | Nonvascularized islet xenograft rejection in a mouse-to-rat combination where the vascularized heart is rapidly rejected. | 1994 | Transplant. Proc. | pmid:7513472 |
| Garcia CD et al. | Renal transplantation in children less than six years old. | 2001 Nov-Dec | Transplant. Proc. | pmid:11750527 |
| Yabuuchi H et al. | Prominent prolongation of islet xenograft survival in combination therapy with FK 506 and 15-deoxyspergualin. | 1991 | Transplant. Proc. | pmid:1703718 |
| First International Congress on FK 506. August 21-24, 1991, Pittsburgh, PA. | 1991 | Transplant. Proc. | pmid:1721253 | |
| Morris-Stiff G et al. | Pharmaco-economic study of FK 506 (Prograf) and cyclosporine A Neoral in cadaveric renal transplantation. | 1998 | Transplant. Proc. | pmid:9636521 |
| Smoter P et al. | Risk factors of acute renal failure after orthotopic liver transplantation: single-center experience. | 2014 | Transplant. Proc. | pmid:25380918 |
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| Yuan QS et al. | Rescue therapy with tacrolimus in renal graft patients with cyclosporine A-induced hepatotoxicity: a preliminary study. | 2000 | Transplant. Proc. | pmid:11119896 |
| Corry RJ et al. | Pancreas transplantation without antibody therapy. | 1998 | Transplant. Proc. | pmid:9532050 |
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| Machado PG et al. | Use of reduced dose of OKT3 (2.5 mg) after renal transplantation. | 2002 | Transplant. Proc. | pmid:11959207 |
| Sugioka A et al. | FK 506 inhibits tolerance induction in mice liver transplantation. | 2005 Jan-Feb | Transplant. Proc. | pmid:15808576 |
| Murase N et al. | Induction of liver, heart, and multivisceral graft acceptance with a short course of FK 506. | 1990 | Transplant. Proc. | pmid:1689906 |
| Hoffman AL et al. | The effect of FK 506 on small intestine allotransplantation in the rat. | 1990 | Transplant. Proc. | pmid:1689907 |
| Bond MMK et al. | Cyclosporine Versus Tacrolimus: Which Calcineurin Inhibitor Has Influence on Cytomegalovirus Infection in Cardiac Transplantation? | 2018 | Transplant. Proc. | pmid:29661443 |
| Abu-Elmagd KM et al. | Monitoring and treatment of intestinal allograft rejection in humans. | 1993 | Transplant. Proc. | pmid:7680150 |
| Farghali H et al. | A biochemical and 31P-NMR investigation of the effect of FK 506 and cyclosporine pretreatment on immobilized hepatocytes perifused with ethanol. | 1991 | Transplant. Proc. | pmid:1721284 |
| Harrison DM et al. | Reduction in hospital stay after liver transplantation. | 1996 | Transplant. Proc. | pmid:8623451 |
| Bekersky I et al. | Bioequivalence of a new strength tacrolimus capsule under development. | 1998 | Transplant. Proc. | pmid:9636591 |
| Kobashigawa JA | Postoperative management following heart transplantation. | 1999 | Transplant. Proc. | pmid:10455966 |
| Koyamada N et al. | Strategy for chronic rejection in recipient of living-related liver transplantation. | 2000 | Transplant. Proc. | pmid:11120102 |
| Kohnle M et al. | Conversion from cyclosporine to tacrolimus in renal transplant recipients with gum hyperplasia. | 1999 | Transplant. Proc. | pmid:10576043 |
| Santos L et al. | New-onset diabetes after transplantation: drug-related risk factors. | 2012 | Transplant. Proc. | pmid:23146462 |
| Watanabe K et al. | Synergistic effect of short-term fractionated lymphoid irradiation with initial high doses of FK506 on the induction of tolerance to kidney allografts in dogs. | 1998 | Transplant. Proc. | pmid:9474940 |
| Torio A et al. | Effect of CYP3A51/3 polymorphism on blood pressure in renal transplant recipients. | 2012 | Transplant. Proc. | pmid:23146466 |
| Asano T et al. | Increased tacrolimus trough levels in association with severe diarrhea, a case report. | 2004 | Transplant. Proc. | pmid:15518758 |
| Kim SJ et al. | Randomized trial of tacrolimus versus cyclosporine in steroid withdrawal in living donor renal transplant recipients. | 2004 | Transplant. Proc. | pmid:15518759 |
| Valdivia LA et al. | Complement and target cells belong to the same species after liver xenografting: protection from hyperacute rejection. | 1994 | Transplant. Proc. | pmid:7518123 |
| Masri M et al. | Prograf five milligrams versus Tacrolimus medis in healthy volunteers: a bioequivalence study. | 2013 | Transplant. Proc. | pmid:24314930 |
| Frank B et al. | Neurotoxicity of FK 506 in liver transplant recipients. | 1993 | Transplant. Proc. | pmid:7682355 |
| Mor E et al. | Weight gain and lipid profile changes in liver transplant recipients: long-term results of the American FK506 Multicenter Study. | 1995 | Transplant. Proc. | pmid:7533363 |
| Matsuura T et al. | Beneficial immunosuppressive effect of combined use of FK 506 and cyclosporine assessed by proliferative responses of cloned human T cells. | 1991 | Transplant. Proc. | pmid:1721316 |
| Mucha K et al. | 36-month follow-up of 75 renal allograft recipients treated with steroids, tacrolimus, and azathioprine or mycophenolate mofetil. | 2003 | Transplant. Proc. | pmid:14529880 |
| Ushigome H et al. | Two cases of tacrolimus-induced alopecia following kidney transplantation. | 1999 | Transplant. Proc. | pmid:10578326 |
| Junge G et al. | Withdrawal of steroids: a randomized prospective study of prednisone and tacrolimus versus mycophenolate mofetil and tacrolimus in liver transplant recipients with autoimmune hepatitis. | 2005 | Transplant. Proc. | pmid:15919434 |
| Huang CT et al. | Higher Variability of Tacrolimus Trough Level Increases Risk of Acute Rejection in Kidney Transplant Recipients. | Transplant. Proc. | pmid:27569931 | |
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| Loh PT et al. | Significant impact of gene polymorphisms on tacrolimus but not cyclosporine dosing in Asian renal transplant recipients. | 2008 | Transplant. Proc. | pmid:18589174 |
| Troisi R et al. | Are reduced tacrolimus dosages needed in the early postoperative period following living donor liver transplantation in adults? | 2002 | Transplant. Proc. | pmid:12176470 |
| Ochiai T et al. | Japanese multicenter studies of FK 506 in renal transplantation. Japanese FK 506 Study Group. | 1995 | Transplant. Proc. | pmid:7533419 |
| Daoud AJ et al. | A comparison of the safety and efficacy of mycophenolate mofetil, prednisone and cyclosporine and mycophenolate mofetil, and prednisone and tacrolimus. | 1998 | Transplant. Proc. | pmid:9865303 |
| Takaya S et al. | Retransplantation of liver: a comparison of FK 506- and cyclosporine-treated patients. | 1991 | Transplant. Proc. | pmid:1721348 |
| Braun F et al. | How to handle mycophenolate mofetil in combination with tacrolimus? | 1998 | Transplant. Proc. | pmid:9865309 |
| Morel P et al. | Liver retransplantation in adults: overall results and determinant factors affecting the outcome. | 1991 | Transplant. Proc. | pmid:1721349 |
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| Yuan-Xin L et al. | Preliminary experience with alemtuzumab induction therapy combined with maintenance low-dose tacrolimus monotherapy in small-bowel transplantation in China. | 2010 Jan-Feb | Transplant. Proc. | pmid:20172275 |
| Altaca G et al. | Effect of low-dose calcineurin inhibitors on acute rejection and graft survival. | 2002 | Transplant. Proc. | pmid:12270320 |
| Colak T et al. | Effect of conversion from cyclosporine to tacrolimus on lipid profiles in renal transplant recipients. | 2002 | Transplant. Proc. | pmid:12270321 |
| Woodside KJ et al. | Conversion from cyclosporine to tacrolimus results in improved creatinine but does not alter lipid profile. | 2005 | Transplant. Proc. | pmid:15919491 |
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| Squifflet JP et al. | Safe withdrawal of corticosteroids or mycophenolate mofetil: results of a large, prospective, multicenter, randomized study. | 2002 | Transplant. Proc. | pmid:12176495 |
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| Ye Q et al. | Persistence of donor cells and incidence of graft-versus-host disease after simultaneous small bowel and bone marrow transplantation. | 1996 | Transplant. Proc. | pmid:8907895 |
| Waller JR et al. | Primary immunosuppression with tacrolimus is associated with a reduction in renal allograft fibrosis compared with neoral therapy. | 2002 | Transplant. Proc. | pmid:12176496 |
| Boggi U et al. | Neoral versus prograf in simultaneous pancreas-kidney transplantation with portal venous drainage: three-year results of a single-center, open-label, prospective, randomized pilot study. | 2005 Jul-Aug | Transplant. Proc. | pmid:16182772 |
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| Spada M et al. | A cause of late graft dysfunction after liver transplantation in children: de-novo autoimmune hepatitis. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267495 |
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