Kawazoe H et al. |
Change of the blood concentration of tacrolimus after the switch from fluconazole to voriconazole in patients receiving allogeneic hematopoietic stem cell transplantation. |
2006 |
Biol. Pharm. Bull. |
pmid:17142996
|
Sakamoto Y et al. |
Correlation between neurotoxic events and intracerebral concentration of tacrolimus in rats. |
2000 |
Biol. Pharm. Bull. |
pmid:10963314
|
Miura M et al. |
Inter-laboratory Variability of Current Immunoassay Methods for Tacrolimus among Japanese Hospitals. |
2016 |
Biol. Pharm. Bull. |
pmid:27263473
|
DiMartini AF et al. |
Prospective study of FK506 side effects: anxiety or akathisia? |
1996 |
Biol. Psychiatry |
pmid:8874843
|
Baldari CT et al. |
NF-AT-luciferase reporter T cell lines as tools to screen immunosuppressive drugs. |
1998 |
Biologicals |
pmid:9637743
|
Wang M et al. |
Enteric polymer based on pH-responsive aliphatic polycarbonate functionalized with vitamin E to facilitate oral delivery of tacrolimus. |
2015 |
Biomacromolecules |
pmid:25714622
|
Fathy M et al. |
Impact of CYP3A5 and MDR-1 gene polymorphisms on the dose and level of tacrolimus among living-donor liver transplanted patients: single center experience. |
2016 |
Biomarkers |
pmid:26856709
|
Wang JL et al. |
Delivery of tacrolimus with cationic lipid-assisted nanoparticles for ulcerative colitis therapy. |
2018 |
Biomater Sci |
pmid:29850666
|
Pham TT et al. |
Tissue adhesive FK506-loaded polymeric nanoparticles for multi-layered nano-shielding of pancreatic islets to enhance xenograft survival in a diabetic mouse model. |
2018 |
Biomaterials |
pmid:29128846
|
Jeong JH et al. |
Surface camouflage of pancreatic islets using 6-arm-PEG-catechol in combined therapy with tacrolimus and anti-CD154 monoclonal antibody for xenotransplantation. |
2011 |
Biomaterials |
pmid:21831422
|
Im BH et al. |
The effects of 8-arm-PEG-catechol/heparin shielding system and immunosuppressive drug, FK506 on the survival of intraportally allotransplanted islets. |
2013 |
Biomaterials |
pmid:23261215
|
Zadrazil J et al. |
Protocol biopsy and subclinical rejection in patients after kidney transplantation treated by tacrolimus (Prograf). |
2003 |
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub |
pmid:15037903
|
Krejci K et al. |
Calcineurin inhibitor-induced renal allograft nephrotoxicity. |
2010 |
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub |
pmid:21293540
|
Zadrazil J et al. |
Improvement of cardiovascular risk factors and cosmetic side effects in kidney transplant recipients after conversion to tacrolimus. |
2009 |
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub |
pmid:19365530
|
Zadrazil J et al. |
In vivo oxidized low-density lipoprotein (ox-LDL) aopp and tas after kidney transplantation: a prospective, randomized one year study comparing cyclosporine A and tacrolimus based regiments. |
2012 |
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub |
pmid:22580856
|
Krejci K et al. |
Clinical experience of conversion from cyclosporine to tacrolimus prolonged-release in stabilized kidney transplant patients. |
2016 |
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub |
pmid:27174195
|
Torres IB et al. |
The Interplay between inflammation and fibrosis in kidney transplantation. |
2014 |
Biomed Res Int |
pmid:24991565
|
Zhang J et al. |
Helminth protein vaccine induced follicular T helper cell for enhancement of humoral immunity against Schistosoma japonicum. |
2013 |
Biomed Res Int |
pmid:24308005
|
Thorat A et al. |
Effects of converting tacrolimus formulation from twice-daily to once-daily in liver transplantation recipients. |
2014 |
Biomed Res Int |
pmid:25121091
|
Ko SF et al. |
Therapeutic potential of tacrolimus on acute myocardial infarction in minipigs: analysis with serial cardiac magnetic resonance and changes at histological and protein levels. |
2014 |
Biomed Res Int |
pmid:25114905
|
Al-Harbi NO et al. |
Olmesartan attenuates tacrolimus-induced biochemical and ultrastructural changes in rat kidney tissue. |
2014 |
Biomed Res Int |
pmid:24987695
|
Krzyżowska K et al. |
Which Kidney Transplant Recipients Can Benefit from the Initial Tacrolimus Dose Reduction? |
2018 |
Biomed Res Int |
pmid:29651435
|
Jovanović M and Golušin Z |
Nonsteroidal Topical Immunomodulators in Allergology and Dermatology. |
2016 |
Biomed Res Int |
pmid:27144167
|
Mochizuki N et al. |
Liquid chromatographic method for the determination of sirolimus in blood using electrochemical detection. |
2009 |
Biomed. Chromatogr. |
pmid:18814192
|
Li Q et al. |
Development and validation of a sensitive LC-MS/MS method for determination of tacrolimus on dried blood spots. |
2013 |
Biomed. Chromatogr. |
pmid:22893355
|
Burhenne H et al. |
Quantitative analysis of the antifungal drug anidulafungin by LC-online SPE-MS/MS in human plasma. |
2012 |
Biomed. Chromatogr. |
pmid:22020627
|
Ma L et al. |
Comparison of release and penetration of tacrolimus ointment reference and trial formulation after dermal application to pigs by liquid chromatography-electrospray ionization tandem mass spectrometry. |
2013 |
Biomed. Chromatogr. |
pmid:23657920
|
Qin XL et al. |
Study of the effect of Wuzhi tablet (Schisandra sphenanthera extract) on tacrolimus tissue distribution in rat by liquid chromatography tandem mass spectrometry method. |
2010 |
Biomed. Chromatogr. |
pmid:19693766
|
Xia T et al. |
Targeted metabolomic analysis of 33 amino acids and biogenic amines in human urine by ion-pairing HPLC-MS/MS: Biomarkers for tacrolimus nephrotoxicity after renal transplantation. |
2018 |
Biomed. Chromatogr. |
pmid:29369388
|
Gagliano N et al. |
Differential effect of Cyclosporin A and FK506 on SPARC mRNA expression by human gingival fibroblasts. |
2005 |
Biomed. Pharmacother. |
pmid:15890490
|
Sir G et al. |
Antagonistic Effect of Oxytocin and Tacrolimus Combination on Adipose Tissue - Derived Mesenchymal Stem Cells: Antagonistic effect of oxytocin and tacrolimus. |
2018 |
Biomed. Pharmacother. |
pmid:29136956
|
Ma X et al. |
Inhibition effect of tacrolimus and platelet-derived growth factor-BB on restenosis after vascular intimal injury. |
2017 |
Biomed. Pharmacother. |
pmid:28633129
|
Ori Y et al. |
Effect of immunosuppressive drugs on spontaneous DNA repair in human peripheral blood mononuclear cells. |
2012 |
Biomed. Pharmacother. |
pmid:22795807
|
Lee C et al. |
Treatment of bleomycin-induced pulmonary fibrosis by inhaled tacrolimus-loaded chitosan-coated poly(lactic-co-glycolic acid) nanoparticles. |
2016 |
Biomed. Pharmacother. |
pmid:26898446
|
Fan B et al. |
Prograf produces more benefits for CYP3A5 low expression patients in early stage after kidney transplantation. |
2017 |
Biomed. Pharmacother. |
pmid:28157649
|
von Suesskind-Schwendi M et al. |
Pharmacokinetics of a self-microemulsifying drug delivery system of tacrolimus. |
2013 |
Biomed. Pharmacother. |
pmid:23669280
|
Zhang X et al. |
Current progress of tacrolimus dosing in solid organ transplant recipients: Pharmacogenetic considerations. |
2018 |
Biomed. Pharmacother. |
pmid:29550633
|
Kalam MA and Alshamsan A |
Poly (d, l-lactide-co-glycolide) nanoparticles for sustained release of tacrolimus in rabbit eyes. |
2017 |
Biomed. Pharmacother. |
pmid:28772219
|
Kanda J et al. |
Effects of the calcineurin inhibitors cyclosporine and tacrolimus on bone metabolism in rats. |
2018 |
Biomed. Res. |
pmid:29899188
|
Alag R et al. |
NMR assignments of the FK506-binding domain of FK506-binding protein 35 from Plasmodium vivax. |
2009 |
Biomol NMR Assign |
pmid:19774494
|
Moda TL et al. |
Hologram QSAR model for the prediction of human oral bioavailability. |
2007 |
Bioorg. Med. Chem. |
pmid:17870541
|
Yli-Kauhaluoma J and Janda KD |
Twisted alpha-keto amides as transition-state analogues for acyl-transfer reactions: synthesis of the immunoconjugates. |
1994 |
Bioorg. Med. Chem. |
pmid:7528089
|
Piggott AM et al. |
Rapid isolation of novel FK506 binding proteins from multiple organisms using gDNA and cDNA T7 phage display. |
2009 |
Bioorg. Med. Chem. |
pmid:19740670
|
Mori T et al. |
An easy preparation of 'monolithic type' hydrophilic solid phase: capability for affinity resin to isolate target proteins. |
2006 |
Bioorg. Med. Chem. |
pmid:16682207
|
Adalsteinsson H and Bruice TC |
Generation and evaluation of putative neuroregenerative drugs. Part 1: virtual point mutations to the polyketide rapamycin. |
2000 |
Bioorg. Med. Chem. |
pmid:10732978
|
Marinec PS et al. |
Synthesis of orthogonally reactive FK506 derivatives via olefin cross metathesis. |
2009 |
Bioorg. Med. Chem. |
pmid:19643614
|
Furuya M et al. |
Reduction of nonspecific binding proteins to self-assembled monolayer on gold surface. |
2006 |
Bioorg. Med. Chem. |
pmid:16314102
|
Ivery MT and Weiler L |
Modeling the interaction between FK506 and FKBP12: a mechanism for formation of the calcineurin inhibitory complex. |
1997 |
Bioorg. Med. Chem. |
pmid:9061187
|
Ivery MT |
A proposed molecular model for the interaction of calcineurin with the cyclosporin A-cyclophilin A complex. |
1999 |
Bioorg. Med. Chem. |
pmid:10465413
|
Xie C et al. |
Vialinin B, a novel potent inhibitor of TNF-alpha production, isolated from an edible mushroom, Thelephora vialis. |
2006 |
Bioorg. Med. Chem. Lett. |
pmid:16901696
|
Iwaoka E et al. |
Improvement of monolithic solid material by utilization of spacer for identification of the target using affinity resins. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19201607
|
Mabuchi M et al. |
Improvement of solid material for affinity resins by application of long PEG spacers to capture the whole target complex of FK506. |
2015 |
Bioorg. Med. Chem. Lett. |
pmid:26025877
|
Mabuchi M et al. |
Selective elution of target protein from affinity resins by a simple reductant with a thiol group. |
2010 |
Bioorg. Med. Chem. Lett. |
pmid:21067925
|
Takahashi Y et al. |
Novel gamma-secretase inhibitors discovered by library screening of in-house synthetic natural product intermediates. |
2006 |
Bioorg. Med. Chem. Lett. |
pmid:16682195
|
Goulet MT et al. |
C32-O-phenalkyl ether derivatives of the immunosuppressant ascomycin: a tether length study. |
1999 |
Bioorg. Med. Chem. Lett. |
pmid:10450986
|
Armstrong HM et al. |
Potent immunosuppressive C32-O-arylethyl ether derivatives of ascomycin with reduced toxicity. |
1999 |
Bioorg. Med. Chem. Lett. |
pmid:10450987
|
Okada K et al. |
Vialinin A is a ubiquitin-specific peptidase inhibitor. |
2013 |
Bioorg. Med. Chem. Lett. |
pmid:23791076
|
Nambu M et al. |
A calcineurin antifungal strategy with analogs of FK506. |
2017 |
Bioorg. Med. Chem. Lett. |
pmid:28412204
|
Hersperger R et al. |
Preparation and immunosuppressive activity of 32-(O)-acylated and 32-(O)-thioacylated analogues of ascomycin. |
1999 |
Bioorg. Med. Chem. Lett. |
pmid:10021934
|
Dubowchik GM et al. |
Fluoresceinated FKBP12 ligands for a high-throughput fluorescence polarization assay. |
2000 |
Bioorg. Med. Chem. Lett. |
pmid:10741553
|
Yang W et al. |
Regulation of gene expression by synthetic dimerizers with novel specificity. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12951089
|
Kawai M et al. |
Studies on an immunosuppressive macrolactam, ascomycin: synthesis of a C-33 hydroxyl derivative. |
1998 |
Bioorg. Med. Chem. Lett. |
pmid:9871515
|
Nishiya Y et al. |
A new efficient method of generating photoaffinity beads for drug target identification. |
2017 |
Bioorg. Med. Chem. Lett. |
pmid:28108248
|
Schultz LW and Clardy J |
Chemical inducers of dimerization: the atomic structure of FKBP12-FK1012A-FKBP12. |
1998 |
Bioorg. Med. Chem. Lett. |
pmid:9871618
|
Goulet MT et al. |
C32-O-imidazol-2-yl-methyl ether derivatives of the immunosuppressant ascomycin with improved therapeutic potential. |
1998 |
Bioorg. Med. Chem. Lett. |
pmid:9873523
|
Takahashi T et al. |
Development of chemically stable solid phases for the target isolation with reduced nonspecific binding proteins. |
2006 |
Bioorg. Med. Chem. Lett. |
pmid:16290149
|
Zhao L et al. |
Modeling and synthesis of non-cyclic derivatives of GPI-1046 as potential FKBP ligands with neurotrophic properties. |
2006 |
Bioorg. Med. Chem. Lett. |
pmid:16753298
|
Rabinowitz M et al. |
Solid-phase/solution-phase combinatorial synthesis of neuroimmunophilin ligands. |
2000 |
Bioorg. Med. Chem. Lett. |
pmid:10843203
|
Ye YQ et al. |
Design and synthesis of a vialinin A analog with a potent inhibitory activity of TNF-α production and its transformation into a couple of bioprobes. |
2012 |
Bioorg. Med. Chem. Lett. |
pmid:22410084
|
Wang YH et al. |
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism. |
2005 |
Bioorg. Med. Chem. Lett. |
pmid:15990295
|
Jogiraju VK et al. |
Application of physiologically based pharmacokinetic modeling to predict drug disposition in pregnant populations. |
2017 |
Biopharm Drug Dispos |
pmid:28474821
|
Watanabe N et al. |
The possible clinical impact of risperidone on P-glycoprotein-mediated transport of tacrolimus: A case report and in vitro study. |
2018 |
Biopharm Drug Dispos |
pmid:29055041
|
Miao LY et al. |
Association study of ABCB1 and CYP3A5 gene polymorphisms with sirolimus trough concentration and dose requirements in Chinese renal transplant recipients. |
2008 |
Biopharm Drug Dispos |
pmid:17941052
|
Frassetto L et al. |
Changes in clearance, volume and bioavailability of immunosuppressants when given with HAART in HIV-1 infected liver and kidney transplant recipients. |
2013 |
Biopharm Drug Dispos |
pmid:24030928
|
Pietruck F et al. |
Evaluation of the effect of candesartan cilexetil on the steady-state pharmacokinetics of tacrolimus in renal transplant patients. |
2005 |
Biopharm Drug Dispos |
pmid:15768377
|
Ohtani H et al. |
Bottom-up modeling and simulation of tacrolimus clearance: prospective investigation of blood cell distribution, sex and CYP3A5 expression as covariates and assessment of study power. |
2011 |
Biopharm Drug Dispos |
pmid:22028295
|
Miura M et al. |
Influence of rabeprazole and lansoprazole on the pharmacokinetics of tacrolimus in relation to CYP2C19, CYP3A5 and MDR1 polymorphisms in renal transplant recipients. |
2007 |
Biopharm Drug Dispos |
pmid:17377957
|
Barter ZE et al. |
Determination of a quantitative relationship between hepatic CYP3A5*1/*3 and CYP3A4 expression for use in the prediction of metabolic clearance in virtual populations. |
2010 |
Biopharm Drug Dispos |
pmid:21104927
|
Takada K et al. |
Distribution characteristics of immunosuppressants FK506 and cyclosporin A in the blood compartment. |
1993 |
Biopharm Drug Dispos |
pmid:7508273
|
Yamada H et al. |
Simvastatin-tacrolimus and simvastatin-cyclosporin interactions in rats. |
1998 |
Biopharm Drug Dispos |
pmid:9673778
|
Oda K and Yamano K |
Effect of telaprevir on the metabolism and hepatic uptake of tacrolimus (FK506). |
2014 |
Biopharm Drug Dispos |
pmid:25059890
|
Takada K et al. |
Distribution kinetics of FK-506, a novel immunosuppressant, after intravenous administration to rats in comparison with cyclosporin A. |
1992 |
Biopharm Drug Dispos |
pmid:1379839
|
Oda K et al. |
In vitro-in vivo extrapolations to evaluate the effect of concomitant drugs on tacrolimus (FK506) exposure. |
2015 |
Biopharm Drug Dispos |
pmid:25600613
|
Oda K et al. |
In vitro experimental system for evaluating inhibitory effect of investigational drugs on P-glycoprotein-mediated transcellular transport of tacrolimus (FK506). |
2014 |
Biopharm Drug Dispos |
pmid:24822242
|
Anderson JS et al. |
Statistical allosteric coupling to the active site indole ring flip equilibria in the FK506-binding domain. |
2014 |
Biophys. Chem. |
pmid:25016286
|
Kovermann M and Balbach J |
Dynamic control of the prolyl isomerase function of the dual-domain SlyD protein. |
2013 |
Biophys. Chem. |
pmid:23268194
|
Sobie EA et al. |
Termination of cardiac Ca(2+) sparks: an investigative mathematical model of calcium-induced calcium release. |
2002 |
Biophys. J. |
pmid:12080100
|
Wang J et al. |
Absolute binding free energy calculations using molecular dynamics simulations with restraining potentials. |
2006 |
Biophys. J. |
pmid:16844742
|
Sun F et al. |
Design and structure-based study of new potential FKBP12 inhibitors. |
2003 |
Biophys. J. |
pmid:14581219
|
Silva ND and Prendergast FG |
Tryptophan dynamics of the FK506 binding protein: time-resolved fluorescence and simulations. |
1996 |
Biophys. J. |
pmid:8785272
|
Wagenknecht T et al. |
Cryoelectron microscopy resolves FK506-binding protein sites on the skeletal muscle ryanodine receptor. |
1996 |
Biophys. J. |
pmid:8785329
|
Lee MS and Olson MA |
Calculation of absolute protein-ligand binding affinity using path and endpoint approaches. |
2006 |
Biophys. J. |
pmid:16284269
|
Ma J et al. |
Rectification of skeletal muscle ryanodine receptor mediated by FK506 binding protein. |
1995 |
Biophys. J. |
pmid:8599646
|
Xu RX et al. |
1H, 13C, and 15N assignments and secondary structure of the FK506 binding protein when bound to ascomycin. |
1993 |
Biopolymers |
pmid:7682113
|
Taylor P et al. |
Conformational polymorphism in peptidic and nonpeptidic drug molecules. |
1996 |
Biopolymers |
pmid:9101762
|
Moore JM |
NMR techniques for characterization of ligand binding: utility for lead generation and optimization in drug discovery. |
1999 |
Biopolymers |
pmid:10516573
|
Wang XJ and Etzkorn FA |
Peptidyl-prolyl isomerase inhibitors. |
2006 |
Biopolymers |
pmid:16302169
|
Sugawara Y et al. |
Once-daily tacrolimus in living donor liver transplant recipients. |
2011 |
Biosci Trends |
pmid:21914950
|
Uyeda M et al. |
Pentalenolactone I and hygromycin A, immunosuppressants produced by Streptomyces filipinensis and Streptomyces hygroscopicus. |
2001 |
Biosci. Biotechnol. Biochem. |
pmid:11440152
|
Kume K et al. |
Screening for a gene deletion mutant whose temperature sensitivity is suppressed by FK506 in budding yeast and its application for a positive screening for drugs inhibiting calcineurin. |
2015 |
Biosci. Biotechnol. Biochem. |
pmid:25614218
|