Fukuda T et al. |
Inhibition of antigen-induced late asthmatic response and bronchial hyperresponsiveness by cyclosporin and FK 506. |
1991 |
Int. Arch. Allergy Appl. Immunol. |
pmid:1718889
|
Murase N et al. |
FK 506 prevents spontaneous diabetes in the BB rat. |
1991 |
Transplant. Proc. |
pmid:1703705
|
Meiser BM et al. |
Effects of cyclosporin, FK506, and rapamycin on graft-vessel disease. |
1991 |
Lancet |
pmid:1719321
|
Watanabe K et al. |
Donor bone marrow cell facilitates induction of tolerance to kidney allografts in dogs treated with fractionated lymphoid irradiation and FK 506. |
1991 |
Transplant. Proc. |
pmid:1703706
|
Jorgensen WL |
Rusting of the lock and key model for protein-ligand binding. |
1991 |
Science |
pmid:1719636
|
Kobayashi N et al. |
Significance of pancreatic allograft rejection in swine abdominal organ cluster transplantation. |
1991 |
Transplant. Proc. |
pmid:1703707
|
Keenan RJ et al. |
Immunosuppressive properties of thalidomide. Inhibition of in vitro lymphocyte proliferation alone and in combination with cyclosporine or FK506. |
1991 |
Transplantation |
pmid:1719668
|
Strasser S et al. |
The effect of FK 506 on canine pancreatic islet cell function in beagle dogs. |
1991 |
Transplant. Proc. |
pmid:1703709
|
Cryan J et al. |
FKBP, the binding protein for the immunosuppressive drug, FK-506, is not an inhibitor of protein kinase C activity. |
1991 |
Biochem. Biophys. Res. Commun. |
pmid:1719972
|
Ryu S and Yasunami Y |
Prevention of immune rejection in rat islet allografts by continuous SC administration of FK 506 using a mini-osmotic pump. |
1991 |
Transplant. Proc. |
pmid:1703710
|
Karlsson H et al. |
The immunosuppressive agent FK506 inhibits in vitro expression of membrane-bound and soluble interleukin-2 receptors on resting but not on activated human lymphocytes. |
1991 |
Immunol. Lett. |
pmid:1720417
|
Alejandro R et al. |
Combined liver-islet allotransplantation in man under FK 506. |
1991 |
Transplant. Proc. |
pmid:1703712
|
|
FK-506 shows similar graft survival rate to cyclosporine but fewer side effects: Pitt transplant team. |
1991 |
Nephrol News Issues |
pmid:1720511
|
Ito T et al. |
The mechanism of tolerance induced by a perioperative injection of bone marrow cells and a brief course of FK 506. |
1991 |
Transplant. Proc. |
pmid:1703716
|
|
The discovery of FK-506 and U.S. development. |
1991 |
Nephrol News Issues |
pmid:1720512
|
Zheng B et al. |
Effects of the new and highly active immunosuppressant, rapamycin, on lymphoid tissues and cells in vivo. |
1991 |
Transplant. Proc. |
pmid:1703717
|
Ali Shah I et al. |
Effects of FK 506 on human hepatic microsomal cytochrome P-450-dependent drug metabolism in vitro. |
1991 |
Transplant. Proc. |
pmid:1721276
|
Moochhala SM et al. |
Inhibition of drug metabolism in rat and human liver microsomes by FK 506 and cyclosporine. |
1991 |
Transplant. Proc. |
pmid:1721277
|
Sumpio BE and Phan S |
Nephrotoxic potential of FK 506. |
1991 |
Transplant. Proc. |
pmid:1721278
|
Pichard L et al. |
Effect of FK 506 on human hepatic cytochromes P-450: interaction with CyA. |
1991 |
Transplant. Proc. |
pmid:1721279
|
Christians U et al. |
Interactions of FK 506 and cyclosporine metabolism. |
1991 |
Transplant. Proc. |
pmid:1721280
|
Wu YM et al. |
Interaction between FK 506 and cyclosporine in dogs. |
1991 |
Transplant. Proc. |
pmid:1721281
|
Habucky K et al. |
The pharmacodynamics of pentobarbital following FK 506 therapy. |
1991 |
Transplant. Proc. |
pmid:1721282
|
Zeevi A et al. |
In vitro assessment of FK 506 immunosuppressive activity in transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721307
|
Katz HR et al. |
Mast cell biochemical and functional heterogeneity. |
1991 |
Transplant. Proc. |
pmid:1721308
|
de Paulis A et al. |
Antiinflammatory effect of FK 506 on human basophils. |
1991 |
Transplant. Proc. |
pmid:1721309
|
Su MS and Semerjian A |
Activation of transcription factor NF kappa B in Jurkat cells is inhibited selectively by FK 506 in a signal-dependent manner. |
1991 |
Transplant. Proc. |
pmid:1721310
|
Andersson J et al. |
The effects of FK 506 on cytokine production are dependent on the mode of cell activation. |
1991 |
Transplant. Proc. |
pmid:1721311
|
Wang SC et al. |
FK 506, rapamycin, and cyclosporine: effects on IL-4 and IL-10 mRNA levels in a T-helper 2 cell line. |
1991 |
Transplant. Proc. |
pmid:1721312
|
Woo J et al. |
Kinetics of early T-cell repopulation in the mouse following syngeneic bone marrow transplantation: FK 506 causes a maturational defect of CD4+ CD8- T cells. |
1991 |
Transplant. Proc. |
pmid:1721313
|
McCarthy SA et al. |
Effects of FK 506 and cyclosporine on T-cell tolerance: inhibition of a "protective" mechanism that regulates activation-induced apoptosis in developing thymocytes. |
1991 |
Transplant. Proc. |
pmid:1721314
|
Zeevi A et al. |
Comparative in vitro studies on the immunosuppressive activities of mycophenolic acid, bredinin, FK 506, cyclosporine, and rapamycin. |
1991 |
Transplant. Proc. |
pmid:1721315
|
Rucay P et al. |
FK 506 rescue therapy for refractory acute rejection in five liver recipients. |
1991 |
Transplant. Proc. |
pmid:1721340
|
Macleod AM and Thomson AW |
FK 506: an immunosuppressant for the 1990s? |
1991 |
Lancet |
pmid:1702172
|
Reding R et al. |
Compassionate use of FK 506 in pediatric liver transplantation: a pilot study. |
1991 |
Transplant. Proc. |
pmid:1721341
|
Uemoto S et al. |
Experience with FK 506 in living related donor liver transplantation. |
1991 |
Transplant. Proc. |
pmid:1721342
|
Tzakis AG et al. |
FK 506 versus cyclosporine in pediatric liver transplantation. |
1991 |
Transplant. Proc. |
pmid:1721343
|
Mieles LA et al. |
Liver transplantation of American veterans under FK 506 immunosuppression: a preliminary report. |
1991 |
Transplant. Proc. |
pmid:1721344
|
Nakazato P et al. |
Early experience with FK 506 induction immunosuppression--suggestion for using oral FK 506. |
1991 |
Transplant. Proc. |
pmid:1721345
|
Nakamura K et al. |
The lymphocytotoxic crossmatch in liver transplantation: a clinicopathologic analysis. |
1991 |
Transplant. Proc. |
pmid:1721346
|
Wijnen RM et al. |
Toxicity of FK 506 in the cynomolgus monkey: noncorrelation with FK 506 serum levels. |
1991 |
Transplant. Proc. |
pmid:1721371
|
Fung JJ et al. |
Adverse effects associated with the use of FK 506. |
1991 |
Transplant. Proc. |
pmid:1721372
|
Omar G et al. |
FK 506 inhibition of cyclosporine metabolism by human liver microsomes. |
1991 |
Transplant. Proc. |
pmid:1703356
|
Hebert MF et al. |
Efficacy and toxicity of FK 506 for the treatment of resistant rejection in liver transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721373
|
Eiras G et al. |
Effects of FK 506 and cyclosporine on T-cell activation: integrin-mediated adhesion of T cells, proliferation, and maturation of cytotoxic T cells. |
1991 |
Transplant. Proc. |
pmid:1703357
|
|
Clinicopathological evaluation of kidney transplants in patients given a fixed dose of FK 506. Japanese FK 506 Study Group. |
1991 |
Transplant. Proc. |
pmid:1721374
|
Christians U et al. |
Measurement of FK 506 by HPLC and isolation and characterization of its metabolites. |
1991 |
Transplant. Proc. |
pmid:1703358
|
Morris SM et al. |
Disruption of renal function and gene expression by FK 506 and cyclosporine. |
1991 |
Transplant. Proc. |
pmid:1721375
|
Lagodziński Z et al. |
Effect of FK 506 on B-cell responses. |
1991 |
Transplant. Proc. |
pmid:1703359
|
Lieberman KV et al. |
FK 506 is a direct glomeruloconstrictor, as determined by electrical resistance pulse sizing (ERPS). |
1991 |
Transplant. Proc. |
pmid:1721376
|
Demetris AJ et al. |
Histopathology of human renal allograft rejection under FK 506: a comparison with cyclosporine. |
1991 |
Transplant. Proc. |
pmid:1703360
|
Ueda D et al. |
Influence of FK 506 on renal blood flow. |
1991 |
Transplant. Proc. |
pmid:1721377
|
Thomson AW et al. |
The influence of FK 506 on the thymus: implications of drug-induced injury to thymic epithelial cells. |
1991 |
Transplant. Proc. |
pmid:1703361
|
Perico N et al. |
FK 506 does not affect the glomerular filtration rate and renal plasma flow in the rat. |
1991 |
Transplant. Proc. |
pmid:1721378
|
Mieles L et al. |
Glycemia and insulin need following FK 506 rescue therapy in liver transplant recipients. |
1991 |
Transplant. Proc. |
pmid:1703362
|
Jacobs TW et al. |
The effect of FK 506, cyclosporine A, and cyclosporine G on serum 1,25-dihydroxyvitamin D levels. |
1991 |
Transplant. Proc. |
pmid:1721403
|
Abu-Elmagd KM et al. |
Acute hemolytic anemia in liver and bone marrow transplant patients under FK 506 therapy. |
1991 |
Transplant. Proc. |
pmid:1721404
|
Adams CK and Famili P |
A study of the effects of the drug FK 506 on gingival tissues. |
1991 |
Transplant. Proc. |
pmid:1721405
|
Pirsch JD et al. |
Pulmonary infiltrates and eosinophilia in an FK 506 liver transplant recipient. |
1991 |
Transplant. Proc. |
pmid:1721406
|
Shinozuka H et al. |
Effect of FK 506 on experimental liver carcinogenesis. |
1991 |
Transplant. Proc. |
pmid:1721407
|
Pelekanou V et al. |
FK 506 and rapamycin do not affect platelet aggregation or mitochondrial function. |
1991 |
Transplant. Proc. |
pmid:1721408
|
Tai J et al. |
In vivo and in vitro effect of FK 506 on rat Leydig cell function. |
1991 |
Transplant. Proc. |
pmid:1721409
|
Ricordi C et al. |
Human islet allotransplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721410
|
Goebl MG |
The peptidyl-prolyl isomerase, FK506-binding protein, is most likely the 12 kd endogenous inhibitor 2 of protein kinase C. |
1991 |
Cell |
pmid:1706222
|
de Paulis A et al. |
FK-506, a potent novel inhibitor of the release of proinflammatory mediators from human Fc epsilon RI+ cells. |
1991 |
J. Immunol. |
pmid:1706398
|
Griffiths EJ and Halestrap AP |
Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin. |
1991 |
Biochem. J. |
pmid:1706598
|
Brabletz T et al. |
The immunosuppressives FK 506 and cyclosporin A inhibit the generation of protein factors binding to the two purine boxes of the interleukin 2 enhancer. |
1991 |
Nucleic Acids Res. |
pmid:1707162
|
Iwaki Y et al. |
Replacement of donor lymphoid tissue in small-bowel transplants. |
1991 |
Lancet |
pmid:1707470
|
Markus PM et al. |
Effects of in vivo treatment with FK506 on natural killer cells in rats. |
1991 |
Transplantation |
pmid:1707562
|
Lin CS et al. |
FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in human T lymphocytes. |
1991 |
Cell. Immunol. |
pmid:1707760
|
Wada H et al. |
An attempt to induce tolerance to skin grafts in congenic mice with FK 506. |
1991 |
Transplant. Proc. |
pmid:1721435
|
Kuroki H et al. |
Synergistic effect of FK 506 and donor-specific blood transfusion on rat skin but not on composite tissue (limb) allograft survival. |
1991 |
Transplant. Proc. |
pmid:1721436
|
Ito T et al. |
Bone marrow cell- and FK 506-induced donor-specific unresponsiveness in rat heart allografts. |
1991 |
Transplant. Proc. |
pmid:1721437
|
DeValeria PA et al. |
FK 506 fails to reverse moderate cardiac allograft rejection in a canine heterotopic model. |
1991 |
Transplant. Proc. |
pmid:1721438
|
Jiang H et al. |
Prolonged cardiac allograft survival in sensitized rats by low-dose FK 506 in combination with splenectomy. |
1991 |
Transplant. Proc. |
pmid:1721439
|
Sato K et al. |
Comparative study of FK 506, cyclosporine, and triple regimen immunosuppression with FK 506, cyclosporine, and mizoribine. |
1991 |
Transplant. Proc. |
pmid:1721440
|
Katayama Y et al. |
Immunosuppressive effects of FK 506 in rat lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721441
|
Hultsch T et al. |
Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1712484
|
Miyahara H et al. |
Comparative studies of the effects of FK506 and cyclosporin A on passively transferred collagen-induced arthritis in rats. |
1991 |
Clin. Immunol. Immunopathol. |
pmid:1712688
|
McAlpine JB et al. |
Revised NMR assignments for rapamycin. |
1991 |
J. Antibiot. |
pmid:1712766
|
Banerji SS et al. |
The immunosuppressant FK-506 specifically inhibits mitogen-induced activation of the interleukin-2 promoter and the isolated enhancer elements NFIL-2A and NF-AT1. |
1991 |
Mol. Cell. Biol. |
pmid:1712901
|
Markus PM et al. |
FK 506 reverses acute graft-versus-host disease after allogeneic bone marrow transplantation in rats. |
1991 |
Surgery |
pmid:1713358
|
Farley DE et al. |
The effect of two new immunosuppressive agents, FK506 and didemnin B, in murine pregnancy. |
1991 |
Transplantation |
pmid:1713360
|
Vathsala A et al. |
The immunosuppressive antagonism of low doses of FK506 and cyclosporine. |
1991 |
Transplantation |
pmid:1713361
|
Matsuura T et al. |
[Experimental studies on the mode of action of cyclosporine and FK506 assessed by proliferation response of human cloned T lymphocytes]. |
1991 |
Hinyokika Kiyo |
pmid:1721767
|
Morris PJ |
Cyclosporine, FK-506 and other drugs in organ transplantation. |
1991 |
Curr. Opin. Immunol. |
pmid:1721824
|
Lhoëst G et al. |
Isolation and mass spectrometric identification of five metabolites of FK-506, a novel macrolide immunosuppressive agent, from human plasma. |
1991 |
Pharm Acta Helv |
pmid:1722046
|
Nicoletti F et al. |
FK-506 prevents diabetes in diabetes-prone BB/Wor rats. |
1991 |
Int. J. Immunopharmacol. |
pmid:1722192
|
Starzl TE et al. |
[Clinical experience with FK 506]. |
1991 |
Presse Med |
pmid:1722311
|
Granelli-Piperno A and McHugh P |
Characterization of a protein that regulates the DNA-binding activity of NF-AT, the nuclear factor of activated T cells. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1722332
|
Nelson PA et al. |
cDNA encoding murine FK506-binding protein (FKBP): nucleotide and deduced amino acid sequence. |
1991 |
Gene |
pmid:1722474
|
Chen MF et al. |
The influence of FK-506 on the thymus and spleen in normal C3H/He mice: flow cytometric analysis of lymphocyte subpopulations. |
1991 |
Immunol. Lett. |
pmid:1722778
|
McWhinnie DL and Morris PJ |
Combination drug therapies for immunosuppression in transplantation. |
1991 |
Ann. Acad. Med. Singap. |
pmid:1724724
|
Pourtier-Manzanedo A et al. |
FK-506 (fujimycin) reverses the multidrug resistance of tumor cells in vitro. |
1991 |
Anticancer Drugs |
pmid:1724925
|
Nakahama H et al. |
Comparative effects of cyclosporine A and FK-506 on endothelin secretion by a cultured renal cell line, LLC-PK1. |
1991 |
J. Cardiovasc. Pharmacol. |
pmid:1725322
|
Romanowski P et al. |
[Synthetic immunomodulators designed on the basis of natural products of microorganisms]. |
1991 |
Postepy Biochem. |
pmid:1725924
|
Altmeyer A et al. |
Unexpected up-regulation of gene expression by cyclosporin A and FK-506 in a T-cell lymphoma: both immunosuppressants augment Ly-6E antigen induction by interferon-gamma in the presence of ionomycin. |
1991 |
Int. J. Immunopharmacol. |
pmid:1726093
|
Gordon RD et al. |
Liver transplantation at the University of Pittsburgh, 1984 to 1990. |
1991 |
Clin Transpl |
pmid:1726458
|
Jamieson NV et al. |
Orthotopic liver transplantation at Addenbrooke's Hospital Cambridge 1968 to 1991. |
1991 |
Clin Transpl |
pmid:1726459
|
Takahara S et al. |
Survival of cardiac allograft in highly sensitized and nonsensitized rats treated with FK506. |
1991 |
J Clin Lab Immunol |
pmid:1726566
|