Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Silva HT et al. | Long-term follow-up of a phase III clinical trial comparing tacrolimus extended-release/MMF, tacrolimus/MMF, and cyclosporine/MMF in de novo kidney transplant recipients. | 2014 | Transplantation | pmid:24521771 |
Haririan A et al. | Polyomavirus reactivation in native kidneys of pancreas alone allograft recipients. | 2003 | Transplantation | pmid:12717201 |
Selzner N et al. | Antiviral treatment of recurrent hepatitis C after liver transplantation: predictors of response and long-term outcome. | 2009 | Transplantation | pmid:19935376 |
Cendales LC et al. | Composite tissue allotransplantation: development of a preclinical model in nonhuman primates. | 2005 | Transplantation | pmid:16340790 |
Mañez R et al. | Fluconazole therapy in transplant recipients receiving FK506. | 1994 | Transplantation | pmid:7515201 |
Sakr M et al. | Cytomegalovirus infection of the upper gastrointestinal tract following liver transplantation--incidence, location, and severity in cyclosporine- and FK506-treated patients. | 1992 | Transplantation | pmid:1373535 |
First MR | Strategies to minimize immunological and nonimmunological risk factors in the renal transplant population. | 2001 | Transplantation | pmid:11585240 |
Garcia-Criado FJ et al. | Possible tacrolimus action mechanisms in its protector effects on ischemia-reperfusion injury. | 1998 | Transplantation | pmid:9798713 |
Tarumi K et al. | CTLA4IgG treatment induces long-term acceptance of rat small bowel allografts. | 1999 | Transplantation | pmid:10071020 |
Mack-Shipman LR et al. | Reproductive hormones after pancreas transplantation. | 2000 | Transplantation | pmid:11063337 |
Sokal EM et al. | Early signs and risk factors for the increased incidence of Epstein-Barr virus-related posttransplant lymphoproliferative diseases in pediatric liver transplant recipients treated with tacrolimus. | 1997 | Transplantation | pmid:9392308 |
Aulagnon F et al. | Diarrhea after kidney transplantation: a new look at a frequent symptom. | 2014 | Transplantation | pmid:25073040 |
Dell'Antonio G and Randhawa PS | "Striped" pattern of medullary ray fibrosis in allograft biopsies from kidney transplant recipients maintained on tacrolimus. | 1999 | Transplantation | pmid:10030300 |
Krook H et al. | Immunosuppressive drugs in islet xenotransplantation: a tool for gaining further insights in the mechanisms of the rejection process. | 2002 | Transplantation | pmid:12438951 |
Blaheta RA et al. | Mycophenolate mofetil decreases endothelial prostaglandin E2 in response to allogeneic T cells or cytokines. | 2000 | Transplantation | pmid:10830246 |
Kelly PA et al. | Ciprofloxacin does not block the antiproliferative effect of tacrolimus. | 1997 | Transplantation | pmid:9000686 |
Gouraud A et al. | Follow-up of tacrolimus breastfed babies. | 2012 | Transplantation | pmid:22996303 |
Fuchinoue S et al. | Kidney transplantation after liver transplantation from the same donor: four cases of successful steroid withdrawal. | 2002 | Transplantation | pmid:11923698 |
Younes BS et al. | The effect of immunosuppression on posttransplant lymphoproliferative disease in pediatric liver transplant patients. | 2000 | Transplantation | pmid:10919581 |
Cherikh WS et al. | A comparison of discharge immunosuppressive drug regimens in primary cadaveric kidney transplantation. | 2003 | Transplantation | pmid:12923430 |