tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Demyelinating Diseases D003711 15 associated lipids
Testicular Diseases D013733 15 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
HIV Seropositivity D006679 15 associated lipids
Neutropenia D009503 15 associated lipids
Hemorrhage D006470 15 associated lipids
Tremor D014202 15 associated lipids
Encephalitis D004660 15 associated lipids
Stomatitis D013280 14 associated lipids
Vasculitis D014657 14 associated lipids
Carcinoma, Squamous Cell D002294 14 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Uveitis D014605 14 associated lipids
Alopecia D000505 14 associated lipids
Biliary Fistula D001658 13 associated lipids
Urticaria D014581 13 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
Corneal Diseases D003316 13 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Gómez-Bravo MA et al. Influence of donor liver CYP3A4*20 loss-of-function genotype on tacrolimus pharmacokinetics in transplanted patients. 2018 Pharmacogenet. Genomics pmid:29256966
Leiskau C et al. Side effects and efficacy of renal sparing immunosuppression in pediatric liver transplantation-A single center matched cohort study. 2018 Pediatr Transplant pmid:29729061
Pham TT et al. Tissue adhesive FK506-loaded polymeric nanoparticles for multi-layered nano-shielding of pancreatic islets to enhance xenograft survival in a diabetic mouse model. 2018 Biomaterials pmid:29128846
Kamanamool N et al. Comparison of disease activity between tacrolimus and mycophenolate mofetil in lupus nephritis: a randomized controlled trial. 2018 Lupus pmid:29105558
Cuñetti L et al. Chronic Pain Treatment With Cannabidiol in Kidney Transplant Patients in Uruguay. 2018 Transplant. Proc. pmid:29579828
Zeng K et al. Dissolution Test of Tacrolimus Capsule: Effects of Filtration and Glass Adsorption. 2018 AAPS PharmSciTech pmid:28828626
Kim JP et al. The effect of full dose composite tissue allotransplantation immunosuppression on allograft motor nerve regeneration in a rat sciatic nerve model. 2018 Microsurgery pmid:28792625
Gómez-Ríos GA et al. Rapid determination of immunosuppressive drug concentrations in whole blood by coated blade spray-tandem mass spectrometry (CBS-MS/MS). 2018 Anal. Chim. Acta pmid:29254576
Park CS et al. Tetrahydrocurcumin Ameliorates Tacrolimus-Induced Nephrotoxicity Via Inhibiting Apoptosis. 2018 Transplant. Proc. pmid:30401411
Hiramatsu Y et al. Changes in the blood level, efficacy, and safety of tacrolimus in pregnancy and the lactation period in patients with systemic lupus erythematosus. 2018 Lupus pmid:30394835
Kaneko T et al. Comparison of whole-blood tacrolimus concentrations measured by different immunoassay systems. 2018 J. Clin. Lab. Anal. pmid:29974517
Saengram W et al. Extended release versus immediate release tacrolimus in kidney transplant recipients: a systematic review and meta-analysis. 2018 Eur. J. Clin. Pharmacol. pmid:29961086
Marquet P et al. Comparative clinical trial of the variability factors of the exposure indices used for the drug monitoring of two tacrolimus formulations in kidney transplant recipients. 2018 Pharmacol. Res. pmid:29229354
Scherrer M et al. Tacrolimus-induced symmetric drug-related intertriginous and flexural exanthema (SDRIFE). 2018 Contact Derm. pmid:29722025
Del Bello A et al. High tacrolimus intra-patient variability is associated with graft rejection, and donor-specific antibodies occurrence after liver transplantation. 2018 World J. Gastroenterol. pmid:29713132
Cintra-Cabrera M et al. Resistant Cytomegalovirus Infection After Renal Transplantation: Literature Review. 2018 Transplant. Proc. pmid:29579856
Jouve T et al. Tailoring tacrolimus therapy in kidney transplantation. 2018 Expert Rev Clin Pharmacol pmid:29779413
Yang Y et al. Chlormethine Hydrochloride is Not Inferior to Tacrolimus in Treating Steroid-Resistant Nephrotic Syndrome. 2018 Kidney Blood Press. Res. pmid:29402844
Gadby F et al. [Pulmonary granuloma in an immunodepressed patient]. 2018 Rev Mal Respir pmid:29395568
Murad A et al. Primary cutaneous post liver transplant lymphoproliferative disorder (PTLD) successfully treated with radiotherapy. 2018 J Dermatolog Treat pmid:28604230