Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Morello RJ et al. | Remote ischemic preconditioning and tacrolimus in the fetal small bowel transplant in mice. | 2016 | Acta Cir Bras | pmid:27828601 |
Anderson K et al. | A retrospective analysis of pediatric patients with lichen sclerosus treated with a standard protocol of class I topical corticosteroid and topical calcineurin inhibitor. | 2016 | J Dermatolog Treat | pmid:26138407 |
Merino D et al. | Different in vitro proliferation and cytokine-production inhibition of memory T-cell subsets after calcineurin and mammalian target of rapamycin inhibitors treatment. | 2016 | Immunology | pmid:26931075 |
Lee SG et al. | Enhanced topical delivery of tacrolimus by a carbomer hydrogel formulation with transcutol P. | 2016 | Drug Dev Ind Pharm | pmid:26925849 |
Koura-Nishiura A et al. | Clearance of atypical facial necrobiosis lipoidica with tacrolimus ointment. | 2016 | J Eur Acad Dermatol Venereol | pmid:25353715 |
Lee SH et al. | Low-dose mycophenolate mofetil in tablet form or capsule form combined with tacrolimus in the early period after kidney transplantation: a prospective randomized trial
. | 2016 | Clin. Nephrol. | pmid:27781419 |
Cortes M et al. | The use of temporary portocaval shunt as a technical aid in auxiliary orthotopic liver transplantation. | 2016 | Liver Transpl. | pmid:27357622 |
Nascimento J and Machado S | Pediatric-onset necrobiosis lipoidica. | 2016 | Pediatr Int | pmid:26865027 |
Ueno KI et al. | Advantage of administering tacrolimus for improving prognosis of patients with polymyositis and dermatomyositis. | 2016 | Int J Rheum Dis | pmid:27457756 |
Chatterjee S and Agrawal D | Tacrolimus in Corticosteroid-Refractory Vernal Keratoconjunctivitis. | 2016 | Cornea | pmid:27310883 |
Yan L et al. | Donor ABCB1 3435 C>T genetic polymorphisms influence early renal function in kidney transplant recipients treated with tacrolimus. | 2016 | Pharmacogenomics | pmid:26784512 |
Barreto P et al. | Conversion From Twice-Daily to Once-Daily Tacrolimus in Stable Kidney Graft Recipients. | 2016 | Transplant. Proc. | pmid:27742278 |
Wu YJ et al. | Safe One-to-One Dosage Conversion From Twice-Daily to Once-Daily Tacrolimus in Long-Term Stable Recipients After Liver Transplantation. | 2016 | Ann. Transplant. | pmid:26782179 |
Robinson CL et al. | Posaconazole in lung transplant recipients: use, tolerability, and efficacy. | 2016 | Transpl Infect Dis | pmid:26781986 |
RodrÃguez-Lago I et al. | Previous exposure to biologics and C-reactive protein are associated with the response to tacrolimus in inflammatory bowel disease. | 2016 | Rev Esp Enferm Dig | pmid:27604685 |
Pereira M et al. | Hyperacute Rejection in a Kidney Transplant With Negative Crossmatch: A Case Report. | 2016 | Transplant. Proc. | pmid:27742303 |
Rostaing L et al. | Novel Once-Daily Extended-Release Tacrolimus Versus Twice-Daily Tacrolimus in De Novo Kidney Transplant Recipients: Two-Year Results of Phase 3, Double-Blind, Randomized Trial. | 2016 | Am. J. Kidney Dis. | pmid:26717860 |
Shuker N et al. | A Randomized Controlled Trial Comparing the Efficacy of Cyp3a5 Genotype-Based With Body-Weight-Based Tacrolimus Dosing After Living Donor Kidney Transplantation. | 2016 | Am. J. Transplant. | pmid:26714287 |
Spain L et al. | Management of toxicities of immune checkpoint inhibitors. | 2016 | Cancer Treat. Rev. | pmid:26874776 |
Ocampo-Garza J et al. | Acquired Hyperpigmentation and Cicatricial Alopecia. | 2016 | Am. J. Med. Sci. | pmid:27524226 |
Solomon A | Allergic manifestations of contact lens wearing. | 2016 | Curr Opin Allergy Clin Immunol | pmid:27518840 |
Navarro-Villarán E et al. | Differential Antitumoral Properties and Renal-Associated Tissue Damage Induced by Tacrolimus and Mammalian Target of Rapamycin Inhibitors in Hepatocarcinoma: In Vitro and In Vivo Studies. | 2016 | PLoS ONE | pmid:27518575 |
Jung HJ et al. | Improved oral absorption of tacrolimus by a solid dispersion with hypromellose and sodium lauryl sulfate. | 2016 | Int. J. Biol. Macromol. | pmid:26642839 |
Imai Y et al. | Histone deacetylase inhibitor panobinostat induces calcineurin degradation in multiple myeloma. | 2016 | JCI Insight | pmid:27699258 |
Cassuto E et al. | Adherence to and Acceptance of Once-Daily Tacrolimus After Kidney and Liver Transplant: Results From OSIRIS, a French Observational Study. | 2016 | Transplantation | pmid:27653227 |
Elshatory YM et al. | Diagnostic and Therapeutic Challenges. | 2016 | Retina (Philadelphia, Pa.) | pmid:26225484 |
Li X and Sun S | Targeting the fungal calcium-calcineurin signaling network in overcoming drug resistance. | 2016 | Future Med Chem | pmid:27463738 |
Butts AR et al. | Factors associated with optimized tacrolimus dosing in hematopoietic stem cell transplantation. | 2016 | J Oncol Pharm Pract | pmid:25802301 |
Belliere J et al. | Pilot conversion trial from mycophenolic acid to everolimus in ABO-incompatible kidney-transplant recipients with BK viruria and/or viremia. | 2016 | Transpl. Int. | pmid:26575959 |
Zhao CY et al. | External evaluation of published population pharmacokinetic models of tacrolimus in adult renal transplant recipients. | 2016 | Br J Clin Pharmacol | pmid:26574188 |
Grönhagen CM and Tey HL | Meralgia paresthetica successfully treated with topical 0.1% tacrolimus: a case report. | 2016 | Int. J. Dermatol. | pmid:26518996 |
Korobko IV and Lomonosov KM | A pilot comparative study of topical latanoprost and tacrolimus in combination with narrow-band ultraviolet B phototherapy and microneedling for the treatment of nonsegmental vitiligo. | 2016 | Dermatol Ther | pmid:27329330 |
Vadcharavivad S et al. | Validation of a 2-Point Limited Sampling Strategy to Predict the Tacrolimus Area-Under-the-12-Hour-Curve in Kidney Transplant Recipients. | 2016 | Ther Drug Monit | pmid:27328329 |
Wu H et al. | Developmental Neurotoxic Effects of Percutaneous Drug Delivery: Behavior and Neurochemical Studies in C57BL/6 Mice. | 2016 | PLoS ONE | pmid:27606422 |
Luo X et al. | Prediction of tacrolimus metabolism and dosage requirements based on CYP3A4 phenotype and CYP3A5(*)3 genotype in Chinese renal transplant recipients. | 2016 | Acta Pharmacol. Sin. | pmid:26924289 |
Raja R et al. | A prospective study of collapsing focal segmental glomerulosclerosis. | 2016 | Ren Fail | pmid:27266801 |
De Meyer M et al. | Pharmacogenetic-based strategy using de novo tacrolimus once daily after kidney transplantation: prospective pilot study. | 2016 | Pharmacogenomics | pmid:27266721 |
Bagherani N | Comparison of pimecrolimus with clobetasol propionate in the treatment of localized vitiligo. | 2016 | Dermatol Ther | pmid:26445411 |
Ahmad M et al. | Effectiveness of minocycline and FK506 alone and in combination on enhanced behavioral and biochemical recovery from spinal cord injury in rats. | 2016 | Pharmacol. Biochem. Behav. | pmid:27106204 |
Ha DH et al. | Effects of tacrolimus on morphology, proliferation and differentiation of mesenchymal stem cells derived from gingiva tissue. | 2016 | Mol Med Rep | pmid:27177273 |
Jin J et al. | Klotho Deficiency Aggravates Tacrolimus-Induced Renal Injury via the Phosphatidylinositol 3-Kinase-Akt-Forkhead Box Protein O Pathway. | 2016 | Am. J. Nephrol. | pmid:27174564 |
Kim JM et al. | Conversion of once-daily extended-release tacrolimus is safe in stable liver transplant recipients: A randomized prospective study. | 2016 | Liver Transpl. | pmid:26360125 |
Bruns K et al. | Quantitative determination of four immunosuppressants by high resolution mass spectrometry (HRMS). | 2016 | Clin. Chem. Lab. Med. | pmid:26641969 |
Zamorano-Leon JJ et al. | New strategy of tacrolimus administration in animal model based on tacrolimus-loaded microspheres. | 2016 | Transpl. Immunol. | pmid:27102446 |
Dasgupta A et al. | Analytical Performance Evaluation of a New Cobas Tacrolimus Assay on Cobas e411 Analyzer: Comparison of Values Obtained by the CMIA Tacrolimus Assay and a Liquid Chromatography Combined with Tandem Mass Spectrometric Method. | 2016 | Ann. Clin. Lab. Sci. | pmid:27098629 |
Watanabe H et al. | The efficacy of add-on tacrolimus for minor flare in patients with systemic lupus erythematosus: a retrospective study. | 2016 | Lupus | pmid:26296361 |
Shipley CA and Spivakovsky S | Tacrolimus or clobetasol for treatment of oral lichen planus. | 2016 | Evid Based Dent | pmid:27012570 |
Ko DH et al. | Performance Evaluation of a Restored Dimension TACR Assay: An Automated Platform for Measuring the Whole Blood Tacrolimus Concentration. | 2016 | Clin. Lab. | pmid:27012028 |
Tang JT et al. | Pharmacogenetic aspects of the use of tacrolimus in renal transplantation: recent developments and ethnic considerations. | 2016 | Expert Opin Drug Metab Toxicol | pmid:27010623 |
Tron C et al. | A high performance liquid chromatography tandem mass spectrometry for the quantification of tacrolimus in human bile in liver transplant recipients. | 2016 | J Chromatogr A | pmid:27837999 |