tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Staruch MJ et al. | Distinctive calcineurin-dependent (FK506-sensitive) mechanisms regulate the production of the CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES vs IL-2 and TNF-alpha by activated human T cells. | 1998 | Cell. Immunol. | pmid:9878113 |
| Naruse K et al. | Uni-axial cyclic stretch induces c-src activation and translocation in human endothelial cells via SA channel activation. | 1998 | FEBS Lett. | pmid:9877176 |
| Murthy JN et al. | Tacrolimus metabolite cross-reactivity in different tacrolimus assays. | 1998 | Clin. Biochem. | pmid:9876892 |
| Takamatsu H et al. | Neuroprotective effects depend on the model of focal ischemia following middle cerebral artery occlusion. | 1998 | Eur. J. Pharmacol. | pmid:9874163 |
| Goulet MT et al. | C32-O-imidazol-2-yl-methyl ether derivatives of the immunosuppressant ascomycin with improved therapeutic potential. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9873523 |
| Mohri T et al. | Rapid adhesion and spread of non-adherent colon cancer Colo201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A. | 1998 | Cell Struct. Funct. | pmid:9872566 |
| Schultz LW and Clardy J | Chemical inducers of dimerization: the atomic structure of FKBP12-FK1012A-FKBP12. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9871618 |
| Kawai M et al. | Studies on an immunosuppressive macrolactam, ascomycin: synthesis of a C-33 hydroxyl derivative. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9871515 |
| Pascual M et al. | Plasma exchange and tacrolimus-mycophenolate rescue for acute humoral rejection in kidney transplantation. | 1998 | Transplantation | pmid:9869086 |
| Sharma AK and Holder FE | Clostridium difficile diarrhea after use of tacrolimus following renal transplantation. | 1998 | Clin. Infect. Dis. | pmid:9868682 |