tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Pericarditis D010493 6 associated lipids
Blindness D001766 6 associated lipids
Alopecia Areata D000506 6 associated lipids
Gliosis D005911 6 associated lipids
Bronchiolitis D001988 6 associated lipids
Infection D007239 6 associated lipids
Behcet Syndrome D001528 7 associated lipids
Hepatitis C D006526 7 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Dementia, Vascular D015140 7 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Sleep Wake Disorders D012893 7 associated lipids
Facial Dermatoses D005148 7 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Tachycardia D013610 7 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Folliculitis D005499 7 associated lipids
Granuloma, Giant Cell D006101 7 associated lipids
Mycobacterium Infections D009164 7 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Chronic Disease D002908 7 associated lipids
Metaplasia D008679 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Dyslipidemias D050171 7 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Lupus Nephritis D008181 8 associated lipids
Thyroid Diseases D013959 8 associated lipids
Fistula D005402 8 associated lipids
Renal Insufficiency D051437 8 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Opportunistic Infections D009894 8 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Candidiasis, Vulvovaginal D002181 8 associated lipids
Immunologic Deficiency Syndromes D007153 8 associated lipids
Arthritis, Juvenile D001171 8 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Pemphigoid, Bullous D010391 8 associated lipids
Sinusitis D012852 9 associated lipids
Thyroiditis, Autoimmune D013967 9 associated lipids
Leukocytosis D007964 9 associated lipids
Cicatrix D002921 9 associated lipids
Periodontal Pocket D010514 9 associated lipids
Inflammatory Bowel Diseases D015212 9 associated lipids
Urination Disorders D014555 9 associated lipids
Hypertension, Renal D006977 9 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Fatigue D005221 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Xie ZQ et al. [Antipruritic mechanisms of pimecrolimus cream for facial dermatitis in adult women patients]. 2009 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:19317053
Tian T et al. [Effect of tacrolimus on the growth cycle of murine hair follicles]. 2007 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:17536270
Xie ZQ and Lan YZ Effectiveness of pimecrolimus cream for women patients with sensitive skin and its underlying mechanism. 2012 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:22954121
Chen GF et al. [Peripheral nerve regeneration under immunosuppression]. 2002 Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi pmid:11944523
Xiong G et al. [Effects of immunosuppressants on proliferation of pheochromocytoma 12 and L929 cells]. 2007 Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi pmid:17694665
Kang H et al. [Combined immunosuppression of FK506 and RS-61443 in rat limb allotransplantation]. 2003 Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi pmid:12822367
Yu HQ et al. [Study of tacrolimus intranasal treatment for allergic asthma in mice]. 2012 Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi pmid:23484272
Li Q et al. [Experimental study of electrophysiologic effects of regenerative nerve fibres affected by control releasing FK506]. 2010 Zhongguo Gu Shang pmid:21254678
Li Y et al. [Study on the Effect of Immunosuppressive Agent FK506 on Growth and Migration of Lung Cancer Cell]. 2017 Zhongguo Fei Ai Za Zhi pmid:28738959
Zhou Y et al. [Effect of tacrolimus on growth-associated protein-43 expression in the hippocampus of neonatal rats with hypoxic-ischemic brain damage]. 2009 Zhongguo Dang Dai Er Ke Za Zhi pmid:19149927