tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Pemphigus, Benign Familial D016506 3 associated lipids
Ileus D045823 3 associated lipids
Anemia, Refractory D000753 3 associated lipids
Wounds, Stab D014951 3 associated lipids
Uveitis, Intermediate D015867 3 associated lipids
Legionellosis D007876 3 associated lipids
Pityriasis D010915 3 associated lipids
Glomerulonephritis, Membranoproliferative D015432 3 associated lipids
Keratosis, Actinic D055623 3 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Perceptual Disorders D010468 3 associated lipids
Fetal Hypoxia D005311 3 associated lipids
Lichen Planus D008010 3 associated lipids
Toxocariasis D014120 3 associated lipids
Pyoderma Gangrenosum D017511 3 associated lipids
Impetigo D007169 3 associated lipids
Hepatolenticular Degeneration D006527 3 associated lipids
Polyneuropathies D011115 3 associated lipids
Trichomonas Infections D014245 3 associated lipids
Peptic Ulcer Perforation D010439 3 associated lipids
Leukoencephalopathies D056784 3 associated lipids
Nervous System Autoimmune Disease, Experimental D020721 3 associated lipids
Epidermolysis Bullosa D004820 3 associated lipids
Paronychia D010304 3 associated lipids
Facial Neoplasms D005153 3 associated lipids
Gingivitis D005891 3 associated lipids
Gingival Hyperplasia D005885 3 associated lipids
Hemophilia B D002836 3 associated lipids
Pouchitis D019449 3 associated lipids
Cryptococcosis D003453 3 associated lipids
Pemphigus D010392 3 associated lipids
Dysgammaglobulinemia D004406 3 associated lipids
Pterygium D011625 3 associated lipids
Osteochondrodysplasias D010009 3 associated lipids
Adrenal Insufficiency D000309 3 associated lipids
Carpal Tunnel Syndrome D002349 3 associated lipids
Arthritis, Reactive D016918 3 associated lipids
Intestinal Atresia D007409 3 associated lipids
Meningococcal Infections D008589 3 associated lipids
Encephalitis, Viral D018792 3 associated lipids
Foot Dermatoses D005533 3 associated lipids
Hyperkalemia D006947 3 associated lipids
Epstein-Barr Virus Infections D020031 3 associated lipids
Cryptogenic Organizing Pneumonia D018549 3 associated lipids
Immune System Diseases D007154 3 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Hematologic Diseases D006402 3 associated lipids
Anus Diseases D001004 3 associated lipids
Leprosy, Borderline D015439 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Ju WQ et al. [Two-dose steroid combined with two-dose daclizumab and tacrolimus regimen in liver transplant recipients]. 2009 Zhonghua Wai Ke Za Zhi pmid:19781270
Yang FC et al. [Influence of combined cyclosporine A and tacrolimus with 5-fluorouracil on hepatocellular carcinoma rats]. 2003 Zhonghua Wai Ke Za Zhi pmid:12895356
Chen YP et al. [The clinical efficacy and safety of tacrolimus in patients with myasthenia gravis]. 2013 Zhonghua Nei Ke Za Zhi pmid:24266997
Sun L et al. [Effect of FK506 on the cavernous nerve regeneration after injury]. 2005 Zhonghua Nan Ke Xue pmid:15755036
Cao ZG et al. [Effects of different immunodepressants on the sperm parameters of kidney transplant recipients]. 2006 Zhonghua Nan Ke Xue pmid:16755867
Zhao S et al. [Effects of tacrolimus (FK506) on heat-shock proteins 70, Bcl-2 and Bax expression in nervous tissue of acrylamide-induced rat]. 2010 Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi pmid:20465949
Sun YJ and Sun Z [Treatment of erosive oral lichen planus with topical tacrolimus]. 2010 Zhonghua Kou Qiang Yi Xue Za Zhi pmid:20450689
Zhang J et al. [Effects of sirolimus on the growth of transplanted hepatocellular carcinoma]. 2009 Zhonghua Gan Zang Bing Za Zhi pmid:19567017
Qian SK et al. [The prevention and management of cerebrovascular complications in nine cases after orthotopic liver transplantation]. 2005 Zhonghua Gan Zang Bing Za Zhi pmid:16313741
Huang K et al. [Prophylaxis and treatment of chronic graft versus host disease]. 2005 Zhonghua Er Ke Za Zhi pmid:15833186
Deng Z et al. [Early diagnosis and comprehensive treatments of post-transplantation lymphoproliferative disorder after pediatric liver transplantation]. 2014 Zhonghua Er Ke Za Zhi pmid:25224233
Zhou DJ and Wu XC [Meta-analysis of calcineurin inhibitor in the treatment of lupus nephritis]. 2011 Zhonghua Er Ke Za Zhi pmid:21624207
Yao SH et al. [Clinical application of tacrolimus with low-dose prednisone in 21 children with steroid-resistant nephrotic syndrome]. 2011 Zhonghua Er Ke Za Zhi pmid:22336304
Wang ZL et al. [Management of pediatric patients who underwent liver transplantation]. 2007 Zhonghua Er Ke Za Zhi pmid:17880788
Wang HY et al. [Clinical and pathological features of Denys-Drash syndrome: report of 3 cases]. 2012 Zhonghua Er Ke Za Zhi pmid:23302619
Nie F et al. [Post-transplant kidney from C-III donation after cardiac death of children: a clinicopathologic study of 20 cases]. 2016 Zhonghua Bing Li Xue Za Zhi pmid:26879429
Xie SP et al. [Study on the clinical application of wuzhi capsule after renal transplantation]. 2011 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:22013798
Ding CG et al. [Clinical application and exploration on mechanism of action of Cordyceps sinensis mycelia preparation for renal transplantation recipients]. 2009 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:20329604
Gu HY et al. [Significance of calcineurin activation and CD40L expression in patients with active lupus nephritis]. 2005 Zhongguo Ying Yong Sheng Li Xue Za Zhi pmid:21162213
Xie ZQ and Lan YZ Effectiveness of pimecrolimus cream for women patients with sensitive skin and its underlying mechanism. 2012 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:22954121