tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhou Y et al. | [Effect of tacrolimus on growth-associated protein-43 expression in the hippocampus of neonatal rats with hypoxic-ischemic brain damage]. | 2009 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:19149927 |
| Huang WY | [Clinical application and side effects of immunosuppressant]. | 2007 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:17448303 |
| Li Y et al. | [Study on the Effect of Immunosuppressive Agent FK506 on Growth and Migration of Lung Cancer Cell]. | 2017 | Zhongguo Fei Ai Za Zhi | pmid:28738959 |
| Li Q et al. | [Experimental study of electrophysiologic effects of regenerative nerve fibres affected by control releasing FK506]. | 2010 | Zhongguo Gu Shang | pmid:21254678 |
| Yu HQ et al. | [Study of tacrolimus intranasal treatment for allergic asthma in mice]. | 2012 | Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi | pmid:23484272 |
| Chen GF et al. | [Peripheral nerve regeneration under immunosuppression]. | 2002 | Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi | pmid:11944523 |
| Xiong G et al. | [Effects of immunosuppressants on proliferation of pheochromocytoma 12 and L929 cells]. | 2007 | Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi | pmid:17694665 |
| Kang H et al. | [Combined immunosuppression of FK506 and RS-61443 in rat limb allotransplantation]. | 2003 | Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi | pmid:12822367 |
| Xie ZQ et al. | [Antipruritic mechanisms of pimecrolimus cream for facial dermatitis in adult women patients]. | 2009 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:19317053 |
| Wen J et al. | [Regulatory effects of cyclosporin A and tacrolimus on the immunological gene expressions in renal transplant recipients]. | 2012 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:23286399 |
| Tian T et al. | [Effect of tacrolimus on the growth cycle of murine hair follicles]. | 2007 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:17536270 |
| Xie ZQ and Lan YZ | Effectiveness of pimecrolimus cream for women patients with sensitive skin and its underlying mechanism. | 2012 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:22954121 |
| Gu HY et al. | [Significance of calcineurin activation and CD40L expression in patients with active lupus nephritis]. | 2005 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | pmid:21162213 |
| Xie SP et al. | [Study on the clinical application of wuzhi capsule after renal transplantation]. | 2011 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:22013798 |
| Ding CG et al. | [Clinical application and exploration on mechanism of action of Cordyceps sinensis mycelia preparation for renal transplantation recipients]. | 2009 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:20329604 |
| Nie F et al. | [Post-transplant kidney from C-III donation after cardiac death of children: a clinicopathologic study of 20 cases]. | 2016 | Zhonghua Bing Li Xue Za Zhi | pmid:26879429 |
| Huang K et al. | [Prophylaxis and treatment of chronic graft versus host disease]. | 2005 | Zhonghua Er Ke Za Zhi | pmid:15833186 |
| Zhou DJ and Wu XC | [Meta-analysis of calcineurin inhibitor in the treatment of lupus nephritis]. | 2011 | Zhonghua Er Ke Za Zhi | pmid:21624207 |
| Wang ZL et al. | [Management of pediatric patients who underwent liver transplantation]. | 2007 | Zhonghua Er Ke Za Zhi | pmid:17880788 |
| Wang HY et al. | [Clinical and pathological features of Denys-Drash syndrome: report of 3 cases]. | 2012 | Zhonghua Er Ke Za Zhi | pmid:23302619 |