tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ofri R et al. | Clinical evaluation of pimecrolimus eye drops for treatment of canine keratoconjunctivitis sicca: a comparison with cyclosporine A. | 2009 | Vet. J. | pmid:17950639 |
| Kano R et al. | Treatment of sterile panniculitis in a dog. | 2004 | Vet. Rec. | pmid:15134169 |
| Tanaka Y et al. | Suppression of feline coronavirus replication in vitro by cyclosporin A. | 2012 | Vet. Res. | pmid:22546085 |
| Mortola E et al. | The use of two immunosuppressive drugs, cyclosporin A and tacrolimus, to inhibit virus replication and apoptosis in cells infected with feline immunodeficiency virus. | 1998 | Vet. Res. Commun. | pmid:10066129 |
| MistrÃková J et al. | Increased neoplasm development due to immunosuppressive treatment with FK-506 in BALB/C mice persistently infected with the mouse herpesvirus (MHV-72). | 1999 | Viral Immunol. | pmid:10532652 |
| Gambarino S et al. | Human Cytomegalovirus Impact on mir-146a Expression Levels in Kidney Transplant Patients. | 2016 | Viral Immunol. | pmid:27077822 |
| Shen ZY et al. | Variations in the S and P regions of the hepatitis B virus genome under immunosuppression in vitro and in vivo. | 2012 | Viral Immunol. | pmid:22946668 |
| Lanford RE et al. | Comparison of tamarins and marmosets as hosts for GBV-B infections and the effect of immunosuppression on duration of viremia. | 2003 | Virology | pmid:12832204 |
| Franke EK and Luban J | Inhibition of HIV-1 replication by cyclosporine A or related compounds correlates with the ability to disrupt the Gag-cyclophilin A interaction. | 1996 | Virology | pmid:8806510 |
| Mahalingam R et al. | Simian varicella virus reactivation in cynomolgus monkeys. | 2007 | Virology | pmid:17651776 |
| Stremlau M et al. | Cyclophilin A: an auxiliary but not necessary cofactor for TRIM5alpha restriction of HIV-1. | 2006 | Virology | pmid:16643975 |
| Goldfeld AE et al. | Cyclosporin A and FK506 block induction of the Epstein-Barr virus lytic cycle by anti-immunoglobulin. | 1995 | Virology | pmid:7538254 |
| Zhao W et al. | Role of cellular FKBP52 protein in intracellular trafficking of recombinant adeno-associated virus 2 vectors. | 2006 | Virology | pmid:16828834 |
| Juvvadi PR et al. | Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach. | 2017 | Virulence | pmid:27325145 |
| Carbajo-Lozoya J et al. | Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir. | 2014 | Virus Res. | pmid:24566223 |
| Carbajo-Lozoya J et al. | Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506. | 2012 | Virus Res. | pmid:22349148 |
| Kass L et al. | Inhibition of the calcineurin-like protein phosphatase activity in Limulus ventral eye photoreceptor cells alters the characteristics of the spontaneous quantal bumps and the light-mediated inward currents, and enhances arrestin phosphorylation. | 1998 Nov-Dec | Vis. Neurosci. | pmid:9839968 |
| TruneÄka P | [Immunosuppression after liver transplant, now and in future]. | 2013 | Vnitr Lek | pmid:24007221 |
| Bakardzhiev I et al. | Unilateral unique Lupus tumidus: pathogenetic mystery and diagnostic problem. | 2016 | Wien Med Wochenschr | pmid:26762262 |
| Durrant-Finn U et al. | [Pruritus and dryness of the skin in chronic kidney insufficiency and dialysis patients - a review]. | 2009 | Wien Med Wochenschr | pmid:19652938 |