Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Peces R et al. | Alloimmune haemolytic anaemia resulting from anti-A and anti-B antibody induced by group O graft in renal transplant recipients. | 1998 | Nephrol. Dial. Transplant. | pmid:9681751 |
Medh RD et al. | Agonist-specific modulation of glucocorticoid receptor-mediated transcription by immunosuppressants. | 1998 | Mol. Cell. Endocrinol. | pmid:9685211 |
Tsuzuki S et al. | FK506 (tacrolimus) inhibits extravasation of lymphoid cells by abrogating VLA-4/VCAM-1 mediated transendothelial migration. | 1998 | FEBS Lett. | pmid:9688583 |
Kilmartin DJ et al. | Tacrolimus (FK506) in failed cyclosporin A therapy in endogenous posterior uveitis. | 1998 | Ocul. Immunol. Inflamm. | pmid:9689640 |
Ding JM et al. | A neuronal ryanodine receptor mediates light-induced phase delays of the circadian clock. | 1998 | Nature | pmid:9690474 |
Moriwaki A et al. | An immunosuppressant, FK506, protects against neuronal dysfunction and death but has no effect on electrographic and behavioral activities induced by systemic kainate. | 1998 | Neuroscience | pmid:9692722 |
Mihatsch MJ et al. | The side-effects of ciclosporine-A and tacrolimus. | 1998 | Clin. Nephrol. | pmid:9696431 |
Rejto PA and Verkhivker GM | Molecular anchors with large stability gaps ensure linear binding free energy relationships for hydrophobic substituents. | 1998 | Pac Symp Biocomput | pmid:9697196 |
[Tacrolimus in kidney transplantation. Bürgenstock, Switzerland, 20 March 1998]. | 1998 | Dtsch. Med. Wochenschr. | pmid:9697633 | |
Matsumoto T et al. | Influence of FK506 on experimental atherosclerosis in cholesterol-fed rabbits. | 1998 | Atherosclerosis | pmid:9699896 |
Duraj F et al. | [Intestinal transplantation. The first Swedish transplantation of the small intestine in an adult patient with pseudoobstruction]. | 1998 | Lakartidningen | pmid:9700261 |
Gruessner RW et al. | Donor-specific portal blood transfusion in intestinal transplantation: a prospective, preclinical large animal study. | 1998 | Transplantation | pmid:9701258 |
Garg UC et al. | Comparison of the Abbott IMx Tacrolimus I and Tacrolimus II assays. | 1998 | Clin. Chem. | pmid:9702984 |
Xu M et al. | Effect of peritransplant FTY720 alone or in combination with post-transplant tacrolimus in a rat model of cardiac allotransplantation. | 1998 | Transpl. Int. | pmid:9704394 |
Stone JH et al. | Outcome of renal transplantation in ninety-seven cyclosporine-era patients with systemic lupus erythematosus and matched controls. | 1998 | Arthritis Rheum. | pmid:9704643 |
Ogawa T et al. | Osteoblastic differentiation is enhanced by rapamycin in rat osteoblast-like osteosarcoma (ROS 17/2.8) cells. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9705862 |
Khattab A et al. | Cyclosporins: lack of correlation between antischistosomal properties and inhibition of cyclophilin isomerase activity. | 1998 | Exp. Parasitol. | pmid:9709036 |
White MH et al. | Randomized, double-blind clinical trial of amphotericin B colloidal dispersion vs. amphotericin B in the empirical treatment of fever and neutropenia. | 1998 | Clin. Infect. Dis. | pmid:9709879 |
Ruetz S | Yeast secretory vesicle system for expression and functional characterization of P-glycoproteins. | 1998 | Meth. Enzymol. | pmid:9711569 |
Marsaud V et al. | Dexamethasone and triamcinolone acetonide accumulation in mouse fibroblasts is differently modulated by the immunosuppressants cyclosporin A, FK506, rapamycin and their analogues, as well as by other P-glycoprotein ligands. | 1998 | J. Steroid Biochem. Mol. Biol. | pmid:9712407 |