Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kilian K et al. | FK-506 (tacrolimus) therapy for an unusual SLE-like disease. | 1998 | Transplant. Proc. | pmid:9865322 |
Schorlemmer HU and Kurrle R | Combination therapy of malononitrilamides and tacrolimus (FK 506) induced long-term xenograft survival. | 1998 | Transplant. Proc. | pmid:9865337 |
Ahlmén J et al. | Positive effects of tacrolimus in a case of CIDP. | 1998 | Transplant. Proc. | pmid:9865344 |
Yokoyama I et al. | Immunosuppressant effect on Fas antigen expression and p53 of an experimental tumor. | 1998 | Transplant. Proc. | pmid:9865346 |
Gerauer K et al. | Long-term cardiac allograft survival in mice treated with malononitrilamide 715. | 1998 | Transplant. Proc. | pmid:9865349 |
Odoul F et al. | Massive ingestion of tacrolimus in a young liver transplant patient. | 1998 | Transplant. Proc. | pmid:9865375 |
EscartÃn A et al. | Analysis of pig-MAP after small bowel transplantation in pigs. | 1998 | Transplant. Proc. | pmid:9865377 |
Reis A et al. | Mycophenolate mofetil and FK506: two novel immunosuppressants in murine corneal transplantation. | 1998 | Transplant. Proc. | pmid:9865380 |
Onose J et al. | Ca2+-ATPase inhibitor induces IL-4 and MCP-1 production in RBL-2H3 cells. | 1998 | Immunol. Lett. | pmid:9865597 |
Marone G | Tacrolimus ointment for atopic dermatitis. | 1998 | N. Engl. J. Med. | pmid:9867559 |
Ong CS | Tacrolimus ointment for atopic dermatitis. | 1998 | N. Engl. J. Med. | pmid:9867560 |
Sharma AK and Holder FE | Clostridium difficile diarrhea after use of tacrolimus following renal transplantation. | 1998 | Clin. Infect. Dis. | pmid:9868682 |
Pascual M et al. | Plasma exchange and tacrolimus-mycophenolate rescue for acute humoral rejection in kidney transplantation. | 1998 | Transplantation | pmid:9869086 |
Kawai M et al. | Studies on an immunosuppressive macrolactam, ascomycin: synthesis of a C-33 hydroxyl derivative. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9871515 |
Schultz LW and Clardy J | Chemical inducers of dimerization: the atomic structure of FKBP12-FK1012A-FKBP12. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9871618 |
Mohri T et al. | Rapid adhesion and spread of non-adherent colon cancer Colo201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A. | 1998 | Cell Struct. Funct. | pmid:9872566 |
Goulet MT et al. | C32-O-imidazol-2-yl-methyl ether derivatives of the immunosuppressant ascomycin with improved therapeutic potential. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9873523 |
Takamatsu H et al. | Neuroprotective effects depend on the model of focal ischemia following middle cerebral artery occlusion. | 1998 | Eur. J. Pharmacol. | pmid:9874163 |
Murthy JN et al. | Tacrolimus metabolite cross-reactivity in different tacrolimus assays. | 1998 | Clin. Biochem. | pmid:9876892 |
Naruse K et al. | Uni-axial cyclic stretch induces c-src activation and translocation in human endothelial cells via SA channel activation. | 1998 | FEBS Lett. | pmid:9877176 |