tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Durham HD et al. | The immunosuppressant FK506 prolongs transgene expression in brain following adenovirus-mediated gene transfer. | 1997 | Neuroreport | pmid:9243594 |
| Yu C et al. | Glucocorticoids fail to enhance the effect of FK506 and methotrexate in prevention of graft-versus-host disease after DLA-nonidentical, unrelated marrow transplantation. | 1997 | Bone Marrow Transplant. | pmid:9244417 |
| Floren LC et al. | Tacrolimus oral bioavailability doubles with coadministration of ketoconazole. | 1997 | Clin. Pharmacol. Ther. | pmid:9246018 |
| Cao S et al. | Potential effect of cyclosporin A in formation of cholesterol gallstones in pediatric liver transplant recipients. | 1997 | Dig. Dis. Sci. | pmid:9246038 |
| McKee M et al. | Steroid withdrawal in tacrolimus (FK506)-treated pediatric liver transplant recipients. | 1997 | J. Pediatr. Surg. | pmid:9247215 |
| Marienfeld R et al. | Cyclosporin A interferes with the inducible degradation of NF-kappa B inhibitors, but not with the processing of p105/NF-kappa B1 in T cells. | 1997 | Eur. J. Immunol. | pmid:9247567 |
| Massicot F et al. | Modulation of energy status and cytotoxicity induced by FK506 and cyclosporin A in a renal epithelial cell line. | 1997 | Arch. Toxicol. | pmid:9248632 |
| Newstead CG | Tacrolimus in renal transplantation. | 1997 | Nephrol. Dial. Transplant. | pmid:9249761 |
| Neuhaus P et al. | Tacrolimus-based immunosuppression after liver transplantation: a randomised study comparing dual versus triple low-dose oral regimens. | 1997 | Transpl. Int. | pmid:9249934 |
| Dhawan A et al. | Tacrolimus (FK506) malabsorption: management with fluconazole coadministration. | 1997 | Transpl. Int. | pmid:9249946 |
| Bragado MJ et al. | p70s6k is activated by CCK in rat pancreatic acini. | 1997 | Am. J. Physiol. | pmid:9252447 |
| Lacaille F et al. | Life-threatening food allergy in a child treated with FK506. | 1997 | J. Pediatr. Gastroenterol. Nutr. | pmid:9252915 |
| Newell KA et al. | Association between liver transplantation for Langerhans cell histiocytosis, rejection, and development of posttransplant lymphoproliferative disease in children. | 1997 | J. Pediatr. | pmid:9255199 |
| Tsamandas AC et al. | Central venulitis in the allograft liver: a clinicopathologic study. | 1997 | Transplantation | pmid:9256183 |
| Sher LS et al. | Efficacy of tacrolimus as rescue therapy for chronic rejection in orthotopic liver transplantation: a report of the U.S. Multicenter Liver Study Group. | 1997 | Transplantation | pmid:9256184 |
| Tsamandas AC et al. | Adult heart transplantation under tacrolimus (FK506) immunosuppression: histopathologic observations and comparison to a cyclosporine-based regimen with lympholytic (ATG) induction. | 1997 | J. Heart Lung Transplant. | pmid:9257254 |
| Trede NS et al. | Tacrolimus (FK506) in allogeneic bone marrow transplantation for severe aplastic anemia following orthotopic liver transplantation. | 1997 | Bone Marrow Transplant. | pmid:9257897 |
| Frezza EE et al. | Non-lymphoid cancer after liver transplantation. | 1997 Jul-Aug | Hepatogastroenterology | pmid:9261620 |
| Wang MS et al. | Comparative dose-dependence study of FK506 and cyclosporin A on the rate of axonal regeneration in the rat sciatic nerve. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9262378 |
| Zhang Q et al. | A specific method for the measurement of tacrolimus in human whole blood by liquid chromatography/tandem mass spectrometry. | 1997 | Ther Drug Monit | pmid:9263391 |
| Hickman PE et al. | Clinical chemistry and post-liver-transplant monitoring. | 1997 | Clin. Chem. | pmid:9265907 |
| Paterson DL et al. | Could a herpesvirus mimic tacrolimus-induced leukoencephalopathy? | 1997 | Ann. Neurol. | pmid:9266742 |
| Yoshimoto T et al. | [Leukoencephalopathy probably caused by tacrolimus hydrate after stem cell transplantation in a girl with MDS 7 monosomy]. | 1997 | Rinsho Ketsueki | pmid:9267167 |
| Woodle ES et al. | Reversal of accelerated renal allograft rejection with FK 506. | 1997 | Clin Transplant | pmid:9267710 |
| Ahsan N et al. | Pure red cell aplasia due to parvovirus B19 infection in solid organ transplantation. | 1997 | Clin Transplant | pmid:9267713 |
| Singh N et al. | Bloodstream infections in liver transplant recipients receiving tacrolimus. | 1997 | Clin Transplant | pmid:9267715 |
| Gruessner RW | Tacrolimus in pancreas transplantation: a multicenter analysis. Tacrolimus Pancreas Transplant Study Group. | 1997 | Clin Transplant | pmid:9267719 |
| Sherrington PD et al. | TLiSA1 (PTA1) activation antigen implicated in T cell differentiation and platelet activation is a member of the immunoglobulin superfamily exhibiting distinctive regulation of expression. | 1997 | J. Biol. Chem. | pmid:9268302 |
| Danovitch GM | Cyclosporin or tacrolimus: which agent to choose? | 1997 | Nephrol. Dial. Transplant. | pmid:9269630 |
| Filler G et al. | Pharmacokinetics of tacrolimus (FK 506) in children and adolescents with renal transplants. | 1997 | Nephrol. Dial. Transplant. | pmid:9269646 |
| Alak AM and Moy S | Biological activity of tacrolimus (FK506) and its metabolites from whole blood of kidney transplant patients. | 1997 | Transplant. Proc. | pmid:9270821 |
| Scholler G et al. | Comparison of cyclosporine A and FK506 with regard to complaints and psychosocial characteristics before and after liver transplantation. | 1997 | Transplant. Proc. | pmid:9270822 |
| Pichlmayr R et al. | Three-year follow-up of the European Multicenter Tacrolimus (FK506) Liver Study. | 1997 | Transplant. Proc. | pmid:9270825 |
| Rolfe FG et al. | Cyclosporin A and FK506 reduce interleukin-5 mRNA abundance by inhibiting gene transcription. | 1997 | Am. J. Respir. Cell Mol. Biol. | pmid:9271313 |
| Mayer AD et al. | Multicenter randomized trial comparing tacrolimus (FK506) and cyclosporine in the prevention of renal allograft rejection: a report of the European Tacrolimus Multicenter Renal Study Group. | 1997 | Transplantation | pmid:9275110 |
| Guérette B et al. | Prevention by anti-LFA-1 of acute myoblast death following transplantation. | 1997 | J. Immunol. | pmid:9278346 |
| Butcher SP et al. | Neuroprotective actions of FK506 in experimental stroke: in vivo evidence against an antiexcitotoxic mechanism. | 1997 | J. Neurosci. | pmid:9278529 |
| Vaden SL | Cyclosporine and tacrolimus. | 1997 | Semin. Vet. Med. Surg. Small Anim. | pmid:9283240 |
| Weppler D et al. | Status of liver and gastrointestinal transplantation at the University of Miami. | 1996 | Clin Transpl | pmid:9286568 |
| Meiser BM et al. | Tacrolimus: a superior agent to OKT3 for treating cases of persistent rejection after intrathoracic transplantation. | 1997 | J. Heart Lung Transplant. | pmid:9286771 |
| Morris-Stiff G et al. | Conversion from cyclosporin to tacrolimus in a patient with prolonged acute tubular necrosis. | 1997 | Transpl. Int. | pmid:9287408 |
| Gerlach J et al. | Systemic liberation of interleukin-8 in the perioperative phase of liver transplantation. | 1997 | Transpl. Int. | pmid:9287409 |
| Michel MC et al. | Comparison of old and new IMX assays for monitoring of tacrolimus levels. | 1997 | Transpl. Int. | pmid:9287412 |
| Brunet M | [Tacrolimus (FK506): clinical, pharmacological and analytical aspects]. | 1997 | Med Clin (Barc) | pmid:9289523 |
| Yagi M et al. | Effect of a glutamine-enriched diet on small bowel allograft during immunosuppressive therapy. | 1997 | Nutrition | pmid:9290090 |
| Kramer MR et al. | Dose adjustment and cost of itraconazole prophylaxis in lung transplant recipients receiving cyclosporine and tacrolimus (FK 506). | 1997 | Transplant. Proc. | pmid:9290780 |
| Shapiro R et al. | Reversibility of tacrolimus-induced posttransplant diabetes: an illustrative case and review of the literature. | 1997 | Transplant. Proc. | pmid:9290809 |
| de-la-Serna-Higuera C et al. | Tacrolimus-induced bone marrow suppression. | 1997 | Lancet | pmid:9291912 |
| Yoshikawa H et al. | Fc gammaRIII-mediated regulation of hematopoiesis in murine bone marrow cells by interleukin-3 and CD95 (Fas/Apo-1). | 1997 | Blood | pmid:9292524 |
| Jain A et al. | Pregnancy after liver transplantation under tacrolimus. | 1997 | Transplantation | pmid:9293865 |