Guy S et al. |
Immunosuppression conversion for relief of side effects. |
1994 |
Transplant. Proc. |
pmid:7527956
|
Knoop C et al. |
FK 506 rescue therapy for irreversible airway rejection in heart-lung transplant recipients: report on five cases. |
1994 |
Transplant. Proc. |
pmid:7527957
|
Candinas D et al. |
Efficacy of leflunomide in combination with current immunosuppressive agents in rat cardiac allotransplantation. |
1994 |
Transplant. Proc. |
pmid:7527959
|
|
Reduced incidence of acute, refractory acute, and chronic rejection after liver transplantation with FK506-based immunosuppression. European FK506 Multicentre Liver Study Group. |
1994 |
Transplant. Proc. |
pmid:7527960
|
Nomoto S et al. |
Cardiotoxicity of long-term intravenous administration of FK506 in rabbits: dose relationship and recovery after discontinuance. |
1994 |
Transplant. Proc. |
pmid:7513477
|
Kato H et al. |
Spontaneous proliferation of peripheral blood mononuclear cells as an indicator for insufficient plasma levels of FK 506 in the early phase after liver transplantation. |
1994 |
Transplant. Proc. |
pmid:7513481
|
Nishikawa K et al. |
Experimental studies of vascularized joint allografts in rats. |
1994 |
Transplant. Proc. |
pmid:7513482
|
Fukuzawa M and Okada A |
Analysis of mouse xenogeneic T-cell responses and the effect of FK 506 on these responses and on xeno-skin graft rejection. |
1994 |
Transplant. Proc. |
pmid:7513483
|
Douglas CM et al. |
The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase. |
1994 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7528927
|
Lhoëst G et al. |
Isolation and identification of a FK-506 C36-C37 dihydrodiol from erythromycin-induced rabbit liver microsomes. |
1994 |
J Pharm Biomed Anal |
pmid:7516189
|
Kraus-Friedmann N and Feng L |
Reduction of ryanodine binding and cytosolic Ca2+ levels in liver by the immunosuppressant FK506. |
1994 |
Biochem. Pharmacol. |
pmid:7529023
|
Ohtsuka S et al. |
Experimental rat pancreas transplant: surgical technique and immunological considerations. |
1994 |
Surg. Today |
pmid:7516209
|
Cardenas ME et al. |
Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands. |
1994 |
EMBO J. |
pmid:7529175
|
Hisatomi K et al. |
Limited effectiveness of FK506 administration for ongoing rejection in heterotopic rat heart transplantation. |
1994 |
Surg. Today |
pmid:7516210
|
Burkhalter EL et al. |
Severe neurological complications following orthotopic liver transplantation in patients receiving FK 506 and prednisone. |
1994 |
J. Hepatol. |
pmid:7529272
|
Kawano K et al. |
Evidence that FK506 alleviates ischemia/reperfusion injury to the rat liver: in vivo demonstration for suppression of TNF-a production in response to endotoxemia. |
1994 |
Eur Surg Res |
pmid:7516291
|
Wolter K et al. |
Interaction between FK 506 and clarithromycin in a renal transplant patient. |
1994 |
Eur. J. Clin. Pharmacol. |
pmid:7532134
|
Hashimoto T et al. |
Treatment with FK506 prevents rejection of rat colon allografts. |
1994 |
Transplantation |
pmid:7516586
|
Konishi M et al. |
Effects of FK506 on surface antigen expression by regenerating thymocytes after sublethal irradiation in the rat. |
1994 |
Thymus |
pmid:7532330
|
Shapiro R et al. |
A prospective, randomized trial of FK-506 in renal transplantation--a comparison between double- and triple-drug therapy. |
1994 |
Clin Transplant |
pmid:7532475
|
Todo S et al. |
Intestinal transplantation at the University of Pittsburgh. |
1994 |
Transplant. Proc. |
pmid:7518136
|
Reyes J et al. |
Lymphoproliferative disease after intestinal transplantation under primary FK 506 immunosuppression. |
1994 |
Transplant. Proc. |
pmid:7518137
|
Murase N et al. |
Small bowel transplantation in sensitized recipients: comparison with heart, kidney, and liver grafts. |
1994 |
Transplant. Proc. |
pmid:7518139
|
Fujisaki S et al. |
Effects of preformed antibodies induced by whole blood transfusion on small bowel transplantation. |
1994 |
Transplant. Proc. |
pmid:7518140
|
Platz KP et al. |
Nephrotoxicity following orthotopic liver transplantation. A comparison between cyclosporine and FK506. |
1994 |
Transplantation |
pmid:7518975
|
Cakaloglu Y et al. |
Importance of cytochrome P-450IIIA activity in determining dosage and blood levels of FK 506 and cyclosporine in liver transplant recipients. |
1994 |
Hepatology |
pmid:7519161
|
Luan S et al. |
Light-regulated, tissue-specific immunophilins in a higher plant. |
1994 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7508125
|
Blazar BR et al. |
FK506 inhibits graft-versus-host disease and bone marrow graft rejection in murine recipients of MHC disparate donor grafts by interfering with mature peripheral T cell expansion post-transplantation. |
1994 |
J. Immunol. |
pmid:7519216
|
Laifer SA et al. |
Pregnancy after cardiac transplantation. |
1994 |
Am J Perinatol |
pmid:7519426
|
Tze WJ et al. |
Successful islet allotransplantation in diabetic rats immunosuppressed with FK506: a functional and immunological study. |
1994 |
Metab. Clin. Exp. |
pmid:7510012
|
Yamauchi T |
[Multiple abdominal organ transplantation in swine using FK-506]. |
1994 |
Nihon Geka Gakkai Zasshi |
pmid:7510015
|
Hara Y et al. |
Heterotopic rat heart transplantation to the iliac vessels. |
1994 |
Transplant. Proc. |
pmid:7520632
|
Nozaki S et al. |
Effect of brequinar sodium on accelerated cardiac allograft rejection in presensitized recipients. |
1994 |
Transplant. Proc. |
pmid:7520633
|
Masaoka T |
Problems of bone marrow transplantation in Japan. |
1994 |
Transplant. Proc. |
pmid:7520634
|
Okano K et al. |
Ameliorative effect of FK 506 on cold ischemia reperfusion injury of the rat liver. |
1994 |
Transplant. Proc. |
pmid:7520635
|
Meadows RP et al. |
A computer-based protocol for semiautomated assignments and 3D structure determination of proteins. |
1994 |
J. Biomol. NMR |
pmid:7510556
|
Metcalfe S et al. |
FK506 and cyclosporin A each inhibit antigen-specific signaling in the T cell line 171 in the absence of a calcium signal. |
1994 |
Cell. Immunol. |
pmid:7522130
|
Nichols RA et al. |
Calcineurin-mediated protein dephosphorylation in brain nerve terminals regulates the release of glutamate. |
1994 |
J. Biol. Chem. |
pmid:7522234
|
Calne RY |
Immunosuppression in liver transplantation. |
1994 |
N. Engl. J. Med. |
pmid:7523947
|
Schleuning M et al. |
Inhibition of cyclosporin A/FK506 resistant, lymphokine-induced T-cell activation by phenothiazine derivatives. |
1994 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:7523957
|
Perotti BY et al. |
HPLC assay for FK 506 and two metabolites in isolated rat hepatocytes and rat liver microsomes. |
1994 |
Pharm. Res. |
pmid:7524055
|
|
FDA approved new drug bulletin: aprotinin injection (trasylol), tacrolimus (prograf). |
1994 |
RN |
pmid:7524131
|
Connolly JO et al. |
Renal arteriopathy associated with FK 506 therapy following liver transplantation. |
1994 |
Nephrol. Dial. Transplant. |
pmid:7526278
|
Pham SM et al. |
Cardiac transplantation at the University of Pittsburgh: 1994 update. |
1994 |
Clin Transpl |
pmid:7547531
|
Radanyi C et al. |
The ability of the immunophilin FKBP59-HBI to interact with the 90-kDa heat shock protein is encoded by its tetratricopeptide repeat domain. |
1994 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7526392
|
Abu-Elmagd K et al. |
Hepatic transplantation at the University of Pittsburgh: new horizons and paradigms after 30 years of experience. |
1994 |
Clin Transpl |
pmid:7547533
|
Ko S et al. |
The pharmacokinetic benefits of newly developed liposome-incorporated FK506. |
1994 |
Transplantation |
pmid:7526494
|
Shapiro R et al. |
Renal transplantation at the University of Pittsburgh: the impact of FK506. |
1994 |
Clin Transpl |
pmid:7547544
|
Holländer GA et al. |
Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo. |
1994 |
Transplantation |
pmid:7526495
|
Chavin KD et al. |
Anti-CD2 monoclonal antibodies synergize with FK506 but not with cyclosporine or rapamycin to induce tolerance. |
1994 |
Transplantation |
pmid:7511258
|
Yano S et al. |
Cyclosporin A enhances susceptibility of multi-drug resistant human cancer cells to anti-P-glycoprotein antibody-dependent cytotoxicity of monocytes, but not of lymphocytes. |
1994 |
Jpn. J. Cancer Res. |
pmid:7511575
|
Iwata H et al. |
Suppression of allograft responses by combining alloantigen-specific i.v. pre-sensitization with suboptimal doses of rapamycin. |
1994 |
Int. Immunol. |
pmid:7511931
|
Mayrleitner M et al. |
The calcium release channel of sarcoplasmic reticulum is modulated by FK-506 binding protein: effect of FKBP-12 on single channel activity of the skeletal muscle ryanodine receptor. |
1994 |
Cell Calcium |
pmid:7511990
|
Platz KP et al. |
Nephrotoxicity after orthotopic liver transplantation in cyclosporin A and FK 506-treated patients. |
1994 |
Transpl. Int. |
pmid:11271297
|
Metcalfe S et al. |
FK 506 and cyclosporin each block antigen-induced T cell receptor signalling that is dependent on CD4 co-receptor and operates in the absence of detectable cytoplasmic calcium fluxes. |
1994 |
Transpl. Int. |
pmid:11271304
|
Moutabarrik A et al. |
Effect of immunosuppressive agents FK 506 and cyclosporin and steroids on the expression of IL-6 and its receptor by stimulated lymphocytes and monocytes. |
1994 |
Transpl. Int. |
pmid:11271305
|
Winkler M et al. |
Optimal FK 506 dosage in patients under primary immunosuppression following liver transplantation. |
1994 |
Transpl. Int. |
pmid:11271312
|
Devlin J et al. |
FK 506 primary immunosuppression following emergency liver transplantation for fulminant hepatic failure. European FK 506 Study Liver Group. |
1994 |
Transpl. Int. |
pmid:11271328
|
Lhoëst G et al. |
Isolation and identification of a novel isomerized epoxide metabolite of FK-506 from erythromycin-induced rabbit liver microsomes. |
1993 Sep-Oct |
Drug Metab. Dispos. |
pmid:7694828
|
Iwasaki K et al. |
Isolation, identification, and biological activities of oxidative metabolites of FK506, a potent immunosuppressive macrolide lactone. |
1993 Nov-Dec |
Drug Metab. Dispos. |
pmid:7507815
|
Fukuse T et al. |
Combined therapy with FK-506 and cyclosporine for canine lung allotransplantation: immunosuppressive effects and blood trough levels. |
1993 Nov-Dec |
J. Heart Lung Transplant. |
pmid:7508750
|
Morris RE |
New small molecule immunosuppressants for transplantation: review of essential concepts. |
1993 Nov-Dec |
J. Heart Lung Transplant. |
pmid:7508752
|
Schreier MH |
Immunophilins and immunosuppression. |
1993 Mar-Apr |
Clin. Exp. Rheumatol. |
pmid:7686830
|
Piekoszewski W et al. |
Disposition of tacrolimus (FK 506) in rabbits. Role of red blood cell binding in hepatic clearance. |
1993 Jul-Aug |
Drug Metab. Dispos. |
pmid:7690698
|
Kobayashi J et al. |
A new rat infection-heart transplant model: effect of infection on graft survival studies. |
1993 Jul-Aug |
J. Heart Lung Transplant. |
pmid:7690253
|
Jordan ML et al. |
FK 506 salvage of renal allografts with ongoing rejection failing cyclosporine immunosuppression. |
1993 |
Transplant. Proc. |
pmid:7679827
|
Klintmalm GB et al. |
Prognostic factors for successful conversion from cyclosporine to FK 506-based immunosuppressive therapy for refractory rejection after liver transplantation. US Multicenter FK 506 Liver Study Group. |
1993 |
Transplant. Proc. |
pmid:7679828
|
Lane BC et al. |
Evaluation of calcineurin's role in the immunosuppressive activity of FK 506, related macrolactams, and cyclosporine. |
1993 |
Transplant. Proc. |
pmid:7679829
|
Tamura K et al. |
Suppression of autoimmune thyroid disease by FK 506: influence on thyroid-infiltrating cells, adhesion molecule expression and anti-thyroglobulin antibody production. |
1993 |
Clin. Exp. Immunol. |
pmid:7680293
|
Armitage JM et al. |
A decade (1982 to 1992) of pediatric cardiac transplantation and the impact of FK 506 immunosuppression. |
1993 |
J. Thorac. Cardiovasc. Surg. |
pmid:7680396
|
Randhawa PS et al. |
The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK506. Clinical significance and comparison with cyclosporine. |
1993 |
Am. J. Surg. Pathol. |
pmid:7680544
|
López-Gil JA and GarcÃa Sáiz M |
[FK506: an immunosuppressor for the '90's?]. |
1993 |
Med Clin (Barc) |
pmid:7505871
|
Kagayama A et al. |
Oral absorption of FK506 in rats. |
1993 |
Pharm. Res. |
pmid:7505939
|
Kim YI et al. |
Augmentation of hepatocyte proliferation by immunosuppressant pretherapy is associated with up-regulation of malondialdehyde production. |
1993 |
Res Exp Med (Berl) |
pmid:7506444
|
Hytiroglou P et al. |
FK506 versus cyclosporine as primary immunosuppressive agent for orthotopic liver allograft recipients. Histologic and immunopathologic observations. |
1993 |
Transplantation |
pmid:7506452
|
Hutchison KA et al. |
FK506 binding to the 56-kilodalton immunophilin (Hsp56) in the glucocorticoid receptor heterocomplex has no effect on receptor folding or function. |
1993 |
Biochemistry |
pmid:7682438
|
Shorrock C and Neuberger J |
The changing face of liver transplantation. |
1993 |
Gut |
pmid:7682532
|
Nakajima J |
[The immunosuppressive effects of FK506 on single lung allotransplantation in Japanese monkey (Macaca fuscata)]. |
1993 |
Nihon Kyobu Geka Gakkai Zasshi |
pmid:7690829
|
Wenzel-Seifert K and Seifert R |
Partial inhibition of human neutrophil activation by FK-506 at supratherapeutic concentrations. |
1993 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:7690907
|
Takada K et al. |
Distribution characteristics of immunosuppressants FK506 and cyclosporin A in the blood compartment. |
1993 |
Biopharm Drug Dispos |
pmid:7508273
|
Thomson AW et al. |
Comparative effects of rapamycin, FK 506 and cyclosporine on antibody production, lymphocyte populations and immunoglobulin isotype switching in the rat. |
1993 |
Immunopharmacol Immunotoxicol |
pmid:7693791
|
Tzakis AG et al. |
Intestinal transplantation in children under FK 506 immunosuppression. |
1993 |
J. Pediatr. Surg. |
pmid:7693907
|
Kawauchi M et al. |
Prolonged survival of orthotopically transplanted heart xenograft in infant baboons. |
1993 |
J. Thorac. Cardiovasc. Surg. |
pmid:7693999
|
Lemster B et al. |
Blood lymphocytes of autoimmune disease patients receiving FK506 exhibit normal ex vivo cytokine gene expression and proliferative responses. |
1993 |
Immunol. Lett. |
pmid:7510265
|
Parent SA et al. |
Calcineurin-dependent growth of an FK506- and CsA-hypersensitive mutant of Saccharomyces cerevisiae. |
1993 |
J. Gen. Microbiol. |
pmid:7510323
|
Metcalfe S et al. |
Prodigiosin 25C: effect in in vitro models for T cell activation and T cell cycling and in vivo for rat heart allografts. |
1993 |
Int. Arch. Allergy Immunol. |
pmid:7685216
|
Bumgardner GL and Roberts JP |
New immunosuppressive agents. |
1993 |
Gastroenterol. Clin. North Am. |
pmid:7685324
|
Ahmed SS et al. |
Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporine A and FK-506 in rat and human liver microsomes. |
1993 |
J. Pharmacol. Exp. Ther. |
pmid:7685382
|
Sewell KL |
Immunotherapy and other novel therapies, including biologic response modifiers, apheresis, and dietary modifications. |
1993 |
Curr Opin Rheumatol |
pmid:7685614
|
Henke W and Jung K |
Comparison of the effects of the immunosuppressive agents FK 506 and cyclosporin A on rat kidney mitochondria. |
1993 |
Biochem. Pharmacol. |
pmid:7690566
|
Altmeyer A and Dumont FJ |
Rapamycin inhibits IL-1-mediated interferon-gamma production in the YAC-1 T cell lymphoma. |
1993 |
Cytokine |
pmid:7687472
|
Przepiorka D et al. |
Bronchiolitis obliterans organizing pneumonia in a BMT patient receiving FK506. |
1993 |
Bone Marrow Transplant. |
pmid:7687503
|
Bram RJ et al. |
Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location. |
1993 |
Mol. Cell. Biol. |
pmid:7687744
|
Fesik SW |
NMR structure-based drug design. |
1993 |
J. Biomol. NMR |
pmid:7689377
|
McManus BM et al. |
Direct myocardial injury by enterovirus: a central role in the evolution of murine myocarditis. |
1993 |
Clin. Immunol. Immunopathol. |
pmid:7689428
|
Namiki Y et al. |
Tautomeric phenomenon of a novel potent immunosuppressant (FK506) in solution. I. Isolation and structure determination of tautomeric compounds. |
1993 |
J. Antibiot. |
pmid:7689551
|
Ibarra F et al. |
Bidirectional regulation of Na+,K(+)-ATPase activity by dopamine and an alpha-adrenergic agonist. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7678337
|
Murase N et al. |
Graft-versus-host disease after brown Norway-to-Lewis and Lewis-to-Brown Norway rat intestinal transplantation under FK506. |
1993 |
Transplantation |
pmid:7678353
|
Herold KC et al. |
Inhibition of glucose-stimulated insulin release from beta TC3 cells and rodent islets by an analog of FK506. |
1993 |
Transplantation |
pmid:7678356
|
Holman MJ et al. |
FK506-associated thrombotic thrombocytopenic purpura. |
1993 |
Transplantation |
pmid:7678357
|