Dumont FJ et al. |
Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin. |
1990 |
J. Immunol. |
pmid:1688572
|
Woo J et al. |
Immunosuppressive activity of FK-506 in rats: flow cytometric analysis of lymphocyte populations in blood, spleen and thymus during treatment and following drug withdrawal. |
1990 |
Clin. Exp. Immunol. |
pmid:1689226
|
Dumont FJ et al. |
The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T cells. |
1990 |
J. Immunol. |
pmid:1689353
|
Zeevi A et al. |
Bioassay of plasma specimens from liver transplant patients on FK 506 immunosuppression. |
1990 |
Transplant. Proc. |
pmid:1689902
|
Imventarza O et al. |
Renal transplantation in baboons under FK 506. |
1990 |
Transplant. Proc. |
pmid:1689903
|
Monden M et al. |
A potent immunosuppressive effect of FK 506 in orthotopic liver transplantation in primates. |
1990 |
Transplant. Proc. |
pmid:1689904
|
Ericzon BG et al. |
Pancreaticoduodenal allotransplantation with FK 506 in the cynomolgus monkey. |
1990 |
Transplant. Proc. |
pmid:1689905
|
Murase N et al. |
Induction of liver, heart, and multivisceral graft acceptance with a short course of FK 506. |
1990 |
Transplant. Proc. |
pmid:1689906
|
Hoffman AL et al. |
The effect of FK 506 on small intestine allotransplantation in the rat. |
1990 |
Transplant. Proc. |
pmid:1689907
|
Lee KK et al. |
Successful orthotopic small bowel transplantation with short-term FK 506 immunosuppressive therapy. |
1990 |
Transplant. Proc. |
pmid:1689908
|
Ueda Y et al. |
Induction of graft acceptance after dog kidney or liver transplantation. |
1990 |
Transplant. Proc. |
pmid:1689909
|
Ohara K et al. |
Toxicologic evaluation of FK 506. |
1990 |
Transplant. Proc. |
pmid:1689910
|
Nalesnik MA et al. |
The effect of FK 506 and CyA on the Lewis rat renal ischemia model. |
1990 |
Transplant. Proc. |
pmid:1689911
|
Murase N et al. |
Suppression of allograft rejection with FK506. I. Prolonged cardiac and liver survival in rats following short-course therapy. |
1990 |
Transplantation |
pmid:1696405
|
Propper DJ et al. |
FK506--its influence on anti-class 1 MHC alloantibody responses to blood transfusions. |
1990 |
Transplantation |
pmid:1696409
|
Maruyama M et al. |
Effect of FK506 treatment on allocytolytic T lymphocyte induction in vivo: differential effects of FK506 on L3T4+ and Ly2+ T cells. |
1990 |
Transplantation |
pmid:1696410
|
Standaert RF et al. |
Molecular cloning and overexpression of the human FK506-binding protein FKBP. |
1990 |
Nature |
pmid:1696686
|
Tropschug M et al. |
Isolation and sequence of an FK506-binding protein from N. crassa which catalyses protein folding. |
1990 |
Nature |
pmid:1696687
|
Randall T |
New antirejection drugs anticipated. |
1990 |
JAMA |
pmid:1696999
|
Metcalfe S et al. |
FK 506 and cyclosporine A: early effects on activation and gene induction in mouse spleen cells. |
1990 |
Transplant. Proc. |
pmid:1697107
|
Morris RE et al. |
A study of the contrasting effects of cyclosporine, FK 506, and rapamycin on the suppression of allograft rejection. |
1990 |
Transplant. Proc. |
pmid:1697111
|
Woo J et al. |
Flow cytometric analysis of lymphocyte populations and activation antigen expression in blood and lymphoid tissues of FK 506-treated rats. |
1990 |
Transplant. Proc. |
pmid:1697112
|
Woo J et al. |
Effects of FK 506 and low concentration cyclosporine on human lymphocyte activation antigen expression: a flow cytometric analysis. |
1990 |
Transplant. Proc. |
pmid:1697113
|
Wicker LS et al. |
Suppression of B cell activation by cyclosporin A, FK506 and rapamycin. |
1990 |
Eur. J. Immunol. |
pmid:1700753
|
Sigal NH et al. |
Observations on the mechanism of action of FK-506. A pharmacologic probe of lymphocyte signal transduction. |
1990 |
Biochem. Pharmacol. |
pmid:1700909
|
Hara S et al. |
The effects of a new immunosuppressive agent, FK506, on the glomerular injury in rats with accelerated nephrotoxic serum glomerulonephritis. |
1990 |
Clin. Immunol. Immunopathol. |
pmid:1700936
|
Murase N et al. |
Effect of FK 506 on spontaneous diabetes in BB rats. |
1990 |
Diabetes |
pmid:1700959
|
Kawashima H and Mochizuki M |
Effects of a new immunosuppressive agent, FK 506, on the efferent limb of the immune responses. |
1990 |
Exp. Eye Res. |
pmid:1701148
|
Siekierka JJ et al. |
The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase. |
1990 |
J. Biol. Chem. |
pmid:1701173
|
Johansson A and Möller E |
Evidence that the immunosuppressive effects of FK506 and cyclosporine are identical. |
1990 |
Transplantation |
pmid:1701570
|
Reyes J et al. |
Expressive dysphasia possibly related to FK506 in two liver transplant recipients. |
1990 |
Transplantation |
pmid:1701571
|
Tsuji RF et al. |
Selective immunosuppression of prodigiosin 25-C and FK506 in the murine immune system. |
1990 |
J. Antibiot. |
pmid:1701765
|
Granelli-Piperno A et al. |
The effect of immunosuppressive agents on the induction of nuclear factors that bind to sites on the interleukin 2 promoter. |
1990 |
J. Exp. Med. |
pmid:1701825
|
Collier SJ |
Immunosuppressive drugs. |
1989-1990 |
Curr. Opin. Immunol. |
pmid:2484794
|
McCauley J et al. |
Treatment of cyclosporin-induced haemolytic uraemic syndrome with FK506. |
1989 Dec 23-30 |
Lancet |
pmid:2481200
|
Yoshimura N et al. |
Effect of a new immunosuppressive agent, FK506, on human lymphocyte responses in vitro. I. Inhibition of expression of alloantigen-activated suppressor cells, as well as induction of alloreactivity. |
1989 |
Transplantation |
pmid:2465592
|
Yoshimura N et al. |
Effect of a new immunosuppressive agent, FK506, on human lymphocyte responses in vitro. II. Inhibition of the production of IL-2 and gamma-IFN, but not B cell-stimulating factor 2. |
1989 |
Transplantation |
pmid:2465593
|
Takabayashi K et al. |
Effect of FK-506, a novel immunosuppressive drug on murine systemic lupus erythematosus. |
1989 |
Clin. Immunol. Immunopathol. |
pmid:2466594
|
Morris RE et al. |
Immunopharmacology of FK-506. |
1989 |
Transplant. Proc. |
pmid:2468201
|
Yoshimura N et al. |
A new immunosuppressive agent, FK506, inhibits the expression of alloantigen-activated suppressor cells as well as the induction of alloreactivity. |
1989 |
Transplant. Proc. |
pmid:2468202
|
Thomson AW et al. |
Immunosuppressive activity, T-cell subset analysis, and acute toxicity of FK-506 in rats. |
1989 |
Transplant. Proc. |
pmid:2468203
|
Sanghvi A et al. |
Increased cyclosporine uptake by cells pretreated with FK506 and evidence for binding of both drugs to a common intracellular protein. |
1989 |
Transplant. Proc. |
pmid:2468204
|
Takagishi K et al. |
Effects of FK-506 on collagen arthritis in mice. |
1989 |
Transplant. Proc. |
pmid:2468205
|
Arita C et al. |
Effect of FK 506 (FR 900506) on collagen arthritis in rats: a preliminary report. |
1989 |
Transplant. Proc. |
pmid:2468206
|
Morimoto T et al. |
Blood levels of FK506 after intramuscular and intravenous administration in dogs. |
1989 |
Transplant. Proc. |
pmid:2468207
|
Tsuchimoto S et al. |
Orthotopic liver transplantation in rats receiving FK506. |
1989 |
Transplant. Proc. |
pmid:2468208
|
Yokota K et al. |
Comparative studies of FK506 and cyclosporine in canine orthotopic hepatic allograft survival. |
1989 |
Transplant. Proc. |
pmid:2468209
|
Inagaki K et al. |
Effects of FK506 and 15-deoxyspergualin in rat orthotopic liver transplantation. |
1989 |
Transplant. Proc. |
pmid:2468210
|
Gudas VM et al. |
Comparison of the immunosuppressive and toxic effects of FK506 and cyclosporine in xenograft recipients. |
1989 |
Transplant. Proc. |
pmid:2468211
|
Sato K et al. |
Pancreaticoduodenal allotransplantation with cyclosporine and FK506. |
1989 |
Transplant. Proc. |
pmid:2468212
|
Watanabe K et al. |
Prolongation effect of a small dose of FK506, cyclosporine, or azathioprine on renal allografts in dogs treated with fractionated lymphoid irradiation and donor bone marrow cell infusion. |
1989 |
Transplant. Proc. |
pmid:2468213
|
Sakamoto K et al. |
Analysis of long-term acceptance of xenografts in rats induced by short-term administration of FK506. |
1989 |
Transplant. Proc. |
pmid:2468222
|
Nakajima K et al. |
Effects of 15-deoxyspergualin and FK506 on the histology and survival of hamster-to-rat cardiac xenotransplantation. |
1989 |
Transplant. Proc. |
pmid:2468223
|
Ochiai T et al. |
Comparative studies on the immunosuppressive activity of FK506, 15-deoxyspergualin, and cyclosporine. |
1989 |
Transplant. Proc. |
pmid:2468228
|
Yasunami Y et al. |
Effects of a novel immunosuppressive agent, FK-506, on islet allograft survival in the rat. |
1989 |
Transplant. Proc. |
pmid:2468234
|
Kobayashi C et al. |
Suppression of corneal graft rejection in rabbits by a new immunosuppressive agent, FK-506. |
1989 |
Transplant. Proc. |
pmid:2468254
|
Kuroki H et al. |
Experimental studies of vascularized allogeneic limb transplantation in the rat using a new immunosuppressive agent, FK-506: morphological and immunological analysis. |
1989 |
Transplant. Proc. |
pmid:2468255
|
Arai K et al. |
Prolonged limb allograft survival with short-term treatment with FK-506 in rats. |
1989 |
Transplant. Proc. |
pmid:2468256
|
Ishibashi M et al. |
Immunopharmacologic effects of immunosuppressive agents explored by a new effector monocyte generation assay. |
1989 |
Transplant. Proc. |
pmid:2469228
|
Starzl TE et al. |
Liver transplantation: an unfinished product. |
1989 |
Transplant. Proc. |
pmid:2469232
|
Hatanaka H et al. |
FK-506 related compounds produced by Streptomyces tsukubaensis No. 9993. |
1989 |
J. Antibiot. |
pmid:2470720
|
Gschwendt M et al. |
The immunosuppressant FK-506, like cyclosporins and didemnin B, inhibits calmodulin-dependent phosphorylation of the elongation factor 2 in vitro and biological effects of the phorbol ester TPA on mouse skin in vivo. |
1989 |
Immunobiology |
pmid:2471685
|
Fujii Y et al. |
Effect of a novel immunosuppressive agent, FK506, on mitogen-induced inositol phospholipid degradation in rat thymocytes. |
1989 |
Transplantation |
pmid:2472025
|
Tocci MJ et al. |
The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes. |
1989 |
J. Immunol. |
pmid:2472451
|
Beck Y and Akiyama N |
Effect of FK-506 and cyclosporine on human lymphocyte responses in vitro. |
1989 |
Transplant. Proc. |
pmid:2472695
|
Thomson AW |
FK-506--how much potential? |
1989 |
Immunol. Today |
pmid:2473767
|
Ochiai T et al. |
Optimal serum trough levels of FK506 in renal allotransplantation of the beagle dog. |
1989 |
Transplantation |
pmid:2474208
|
Ochiai T et al. |
Effects of combination treatment with FK506 and cyclosporine on survival time and vascular changes in renal-allograft-recipient dogs. |
1989 |
Transplantation |
pmid:2474209
|
Siekierka JJ et al. |
FK-506, a potent novel immunosuppressive agent, binds to a cytosolic protein which is distinct from the cyclosporin A-binding protein, cyclophilin. |
1989 |
J. Immunol. |
pmid:2474605
|
Thomson AW and Woo J |
Immunosuppressive properties of FK-506 and rapamycin. |
1989 |
Lancet |
pmid:2474733
|
Todo S et al. |
Renal transplantation in baboons under FK 506. |
1989 |
Surgery |
pmid:2474865
|
Kay JE et al. |
Inhibition of T-lymphocyte activation by the immunosuppressive drug FK-506. |
1989 |
Immunology |
pmid:2475433
|
Moriyama S |
[Experimental tracheal reconstruction by allotransplantation]. |
1989 |
Nihon Kyobu Geka Gakkai Zasshi |
pmid:2475555
|
Freedman RB |
Immunosuppression. Convergence of drug action. |
1989 |
Nature |
pmid:2477712
|
Siekierka JJ et al. |
A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin. |
1989 |
Nature |
pmid:2477714
|
Harding MW et al. |
A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase. |
1989 |
Nature |
pmid:2477715
|
Kay JE et al. |
The mechanism of action of the immunosuppressive drug FK-506. |
1989 |
Cell. Immunol. |
pmid:2478301
|
Starzl TE et al. |
FK 506 for liver, kidney, and pancreas transplantation. |
1989 |
Lancet |
pmid:2478846
|
Arai K et al. |
Limb allografts in rats immunosuppressed with FK506. I. Reversal of rejection and indefinite survival. |
1989 |
Transplantation |
pmid:2479130
|
Francavilla A et al. |
Augmentation of rat liver regeneration by FK 506 compared with cyclosporin. |
1989 |
Lancet |
pmid:2479802
|
Walliser P et al. |
Inhibition of murine B-lymphocyte proliferation by the novel immunosuppressive drug FK-506. |
1989 |
Immunology |
pmid:2480331
|
Aoki M et al. |
[Histological observations of immunosuppressive effects of FK-506 in canine lung allotransplantation]. |
1989 |
Bull Chest Dis Res Inst Kyoto Univ |
pmid:2482787
|
Kay JE and Benzie CR |
T lymphocyte activation through the C28 pathway is insensitive to inhibition by the immunosuppressive drug FK-506. |
1989 |
Immunol. Lett. |
pmid:2483716
|
Leonard DK et al. |
Toxicity of FK-506 in human fetal pancreas. |
1989 |
Diabetes |
pmid:2463195
|
Stephen M et al. |
Immunosuppressive activity, lymphocyte subset analysis, and acute toxicity of FK-506 in the rat. A comparative and combination study with cyclosporine. |
1989 |
Transplantation |
pmid:2463701
|
Inamura N et al. |
Immunosuppressive effect of FK506 on collagen-induced arthritis in rats. |
1988 |
Clin. Immunol. Immunopathol. |
pmid:2446810
|
Inamura N et al. |
Prolongation of skin allograft survival in rats by a novel immunosuppressive agent, FK506. |
1988 |
Transplantation |
pmid:2447690
|
Ochiai T et al. |
Studies on FK506 in experimental organ transplantation. |
1988 |
Transplant. Proc. |
pmid:2450414
|
|
Immunosuppression: FK506. |
1988 |
Transplant. Proc. |
pmid:2450415
|
Todo S et al. |
Effect of FK506 in experimental organ transplantation. |
1988 |
Transplant. Proc. |
pmid:2450416
|
Tsuchimoto S et al. |
[Orthotopic liver transplantation in the rat--immunosuppressive effect of FR100906 on the survival of liver allografts]. |
1988 |
Nihon Geka Gakkai Zasshi |
pmid:2452341
|
Nakajima K et al. |
Prolongation of cardiac xenograft survival in rats treated with 15-deoxyspergualin alone and in combination with FK506. |
1988 |
Transplantation |
pmid:2454521
|
Todo S et al. |
Immunosuppression of canine, monkey, and baboon allografts by FK 506: with special reference to synergism with other drugs and to tolerance induction. |
1988 |
Surgery |
pmid:2456627
|
Kawashima H et al. |
Effects of a new immunosuppressive agent, FK506, on experimental autoimmune uveoretinitis in rats. |
1988 |
Invest. Ophthalmol. Vis. Sci. |
pmid:2458329
|
Warty V et al. |
FK506: a novel immunosuppressive agent. Characteristics of binding and uptake by human lymphocytes. |
1988 |
Transplantation |
pmid:2458643
|
Hewitt CW and Black KS |
Comparative studies of FK506 with cyclosporine. |
1988 |
Transplantation |
pmid:2458644
|
Woo J et al. |
Spleen lymphocyte populations and expression of activation markers in rats treated with the potent new immunosuppressive agent FK-506. |
1988 |
Immunology |
pmid:2460401
|
Hatanaka H et al. |
FR-900520 and FR-900523, novel immunosuppressants isolated from a Streptomyces. II. Fermentation, isolation and physico-chemical and biological characteristics. |
1988 |
J. Antibiot. |
pmid:2461926
|
Inamura N et al. |
Immunosuppressive effect of FK506 on experimental allergic encephalomyelitis in rats. |
1988 |
Int. J. Immunopharmacol. |
pmid:2463974
|
Hatanaka H et al. |
FR-900520 and FR-900523, novel immunosuppressants isolated from a Streptomyces. I. Taxonomy of the producing strain. |
1988 |
J. Antibiot. |
pmid:3198493
|