tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Gout D006073 4 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Granuloma, Giant Cell D006101 7 associated lipids
Graves Disease D006111 6 associated lipids
Gynecomastia D006177 6 associated lipids
Hallucinations D006212 4 associated lipids
Hand Dermatoses D006229 5 associated lipids
Hand Injuries D006230 1 associated lipids
Headache D006261 4 associated lipids
Hearing Loss, Bilateral D006312 1 associated lipids
Hearing Loss, Noise-Induced D006317 4 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Cardiomegaly D006332 31 associated lipids
Heart Failure D006333 36 associated lipids
Heart Injuries D006335 6 associated lipids
Hematologic Diseases D006402 3 associated lipids
Hematoma D006406 5 associated lipids
Hematuria D006417 13 associated lipids
Hemolysis D006461 131 associated lipids
Hemolytic-Uremic Syndrome D006463 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Ohye H et al. Effects of immunosuppressant agents on growth hormone release and gene expression. 1998 Endocr. J. pmid:9790238
Bajaj-Elliott M et al. Interactions between stromal cell--derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia. 1998 J. Clin. Invest. pmid:9788959
Masugi T and Otsuka K [Immunosuppressive drugs and calcineurin]. 1998 Tanpakushitsu Kakusan Koso pmid:9788176
Heering P et al. Distal tubular acidosis induced by FK506. 1998 Clin Transplant pmid:9787958
Wu A et al. Outcome of 22 successful pregnancies after liver transplantation. 1998 Clin Transplant pmid:9787957
Peddi VR et al. Use of tacrolimus eliminates acute rejection as a major complication following simultaneous kidney and pancreas transplantation. 1998 Clin Transplant pmid:9787948
Rayes N et al. Pregnancies following liver transplantation--how safe are they? A report of 19 cases under cyclosporine A and tacrolimus. 1998 Clin Transplant pmid:9787947
Nishida T et al. [FK506 for the prophylaxis of graft-versus-host-disease after bone marrow transplantation from HLA-genotypically mismatched unrelated donor]. 1998 Rinsho Ketsueki pmid:9785975
Maestri M et al. [Treatment of the nephrotoxicity of immunosuppressive drugs with insulin-like growth factor-I]. 1998 Minerva Chir pmid:9780630
Motamedi H and Shafiee A The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506. 1998 Eur. J. Biochem. pmid:9780228