tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Precursor Cell Lymphoblastic Leukemia-Lymphoma D054198 10 associated lipids
Dyspnea D004417 10 associated lipids
Hemophilia A D006467 10 associated lipids
Muscular Dystrophies D009136 10 associated lipids
Alveolar Bone Loss D016301 10 associated lipids
Glycosuria D006029 10 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Fatigue D005221 10 associated lipids
Vision Disorders D014786 10 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Long QT Syndrome D008133 10 associated lipids
Neuromuscular Diseases D009468 10 associated lipids
Thinness D013851 11 associated lipids
Shock, Septic D012772 11 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
Dehydration D003681 11 associated lipids
Hyperpigmentation D017495 11 associated lipids
Influenza, Human D007251 11 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Exanthema D005076 11 associated lipids
Uveitis, Anterior D014606 11 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Candidiasis, Oral D002180 11 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Shock D012769 11 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Duodenal Ulcer D004381 12 associated lipids
Keloid D007627 12 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Osteoporosis D010024 12 associated lipids
Retinoblastoma D012175 12 associated lipids
Listeriosis D008088 12 associated lipids
Eye Diseases D005128 12 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Crohn Disease D003424 12 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Hepatitis C, Chronic D019698 12 associated lipids
Skin Neoplasms D012878 12 associated lipids
Rosacea D012393 13 associated lipids
Critical Illness D016638 13 associated lipids
Hypoglycemia D007003 13 associated lipids
Sarcoidosis D012507 13 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Corneal Diseases D003316 13 associated lipids
Biliary Fistula D001658 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Green MD and Michaels MG Tacrolimus: effects and side effects. 1999 Pediatr. Infect. Dis. J. pmid:10223694
Ferrari D et al. P2X7/P2Z purinoreceptor-mediated activation of transcription factor NFAT in microglial cells. 1999 J. Biol. Chem. pmid:10224077
Herr I et al. FK506 prevents stroke-induced generation of ceramide and apoptosis signaling. 1999 Brain Res. pmid:10224298
Charco R et al. Serum cholesterol changes in long-term survivors of liver transplantation: a comparison between cyclosporine and tacrolimus therapy. 1999 Liver Transpl Surg pmid:10226111
Taylor DO et al. A randomized, multicenter comparison of tacrolimus and cyclosporine immunosuppressive regimens in cardiac transplantation: decreased hyperlipidemia and hypertension with tacrolimus. 1999 J. Heart Lung Transplant. pmid:10226898
Torocsik HV et al. FK506-induced leukoencephalopathy in children with organ transplants. 1999 Neurology pmid:10227644
Göthel SF and Marahiel MA Peptidyl-prolyl cis-trans isomerases, a superfamily of ubiquitous folding catalysts. 1999 Cell. Mol. Life Sci. pmid:10228556
Uno T et al. Pharmacokinetic advantages of a newly developed tacrolimus oil-in-water-type emulsion via the enteral route. 1999 Lipids pmid:10230718
Johnston A and Holt DW Therapeutic drug monitoring of immunosuppressant drugs. 1999 Br J Clin Pharmacol pmid:10233195
Vente C et al. Erosive mucosal lichen planus: response to topical treatment with tacrolimus. 1999 Br. J. Dermatol. pmid:10233234
Lyon CC et al. Recalcitrant pyoderma gangrenosum treated with systemic tacrolimus. 1999 Br. J. Dermatol. pmid:10233300
Jolles S et al. Combination oral and topical tacrolimus in therapy-resistant pyoderma gangrenosum. 1999 Br. J. Dermatol. pmid:10233301
Mollison KW et al. A macrolactam inhibitor of T helper type 1 and T helper type 2 cytokine biosynthesis for topical treatment of inflammatory skin diseases. 1999 J. Invest. Dermatol. pmid:10233764
Akahane M et al. Osteogenic phenotype expression of allogeneic rat marrow cells in porous hydroxyapatite ceramics. 1999 J. Bone Miner. Res. pmid:10234577
Stratta RJ et al. Evolution in pancreas transplantation techniques: simultaneous kidney-pancreas transplantation using portal-enteric drainage without antilymphocyte induction. 1999 Ann. Surg. pmid:10235529
Remy I and Michnick SW Clonal selection and in vivo quantitation of protein interactions with protein-fragment complementation assays. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10318894
Genazzani AA et al. Calcineurin controls inositol 1,4,5-trisphosphate type 1 receptor expression in neurons. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10318964
Morioka M et al. Activities of calcineurin and phosphatase 2A in the hippocampus after transient forebrain ischemia. 1999 Brain Res. pmid:10320733
Ferlicot S et al. [Smooth muscle mesentery associated with Epstein-Barr virus (EBV). Report of a case in a child with a liver transplant under FK506 regimen]. 1999 Ann Pathol pmid:10320913
Raofi V et al. A prospective randomized trial comparing the efficacy of tacrolimus versus cyclosporine in black recipients of primary cadaveric renal transplants. 1999 Am. J. Surg. pmid:10326847