tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kakefuda T et al. | Nitrosyl hemoglobin detected by near-infrared spectroscopy in rat liver allografts. | 1999 | Transpl. Int. | pmid:10551995 |
| Chen L et al. | Bastadin 10 stabilizes the open conformation of the ryanodine-sensitive Ca(2+) channel in an FKBP12-dependent manner. | 1999 | J. Biol. Chem. | pmid:10551814 |
| Zoppo A et al. | Trimetazidine counteracts tacrolimus nephrotoxicity in a hypertensive liver transplant patient. | 1999 | Transplantation | pmid:10551656 |
| Pirsch JD | Cytomegalovirus infection and posttransplant lymphoproliferative disease in renal transplant recipients: results of the U.S. multicenter FK506 Kidney Transplant Study Group. | 1999 | Transplantation | pmid:10551653 |
| Rolles K et al. | A pilot study of immunosuppressive monotherapy in liver transplantation: tacrolimus versus microemulsified cyclosporin. | 1999 | Transplantation | pmid:10551650 |
| Ocran KW et al. | Tacrolimus toxicity due to drug interaction with mibefradil in a patient after liver transplantation. | 1999 | Z Gastroenterol | pmid:10549098 |
| Dubernard JM et al. | [The first transplantation of a hand in humans. Early results]. | 1999 | Chirurgie | pmid:10546388 |
| Klein A | Tacrolimus rescue in liver transplant patients with refractory rejection or intolerance or malabsorption of cyclosporine. The US Multicenter FK506 Liver Study Group. | 1999 | Liver Transpl Surg | pmid:10545538 |
| Himukai R et al. | Relationship between the subcellular localization and structures of catalytic domains of FKBP-type PPIases. | 1999 | J. Biochem. | pmid:10544281 |
| Wiedeman PE et al. | Retention of immunosuppressant activity in an ascomycin analogue lacking a hydrogen-bonding interaction with FKBP12. | 1999 | J. Med. Chem. | pmid:10543889 |
| Pearlman DA | Free energy grids: a practical qualitative application of free energy perturbation to ligand design using the OWFEG method. | 1999 | J. Med. Chem. | pmid:10543875 |
| Aoki Y and Kao PN | Erythromycin inhibits transcriptional activation of NF-kappaB, but not NFAT, through calcineurin-independent signaling in T cells. | 1999 | Antimicrob. Agents Chemother. | pmid:10543746 |
| Matsuda J | [Tacrolimus hydrate (tacrolimus)]. | 1999 | Nippon Rinsho | pmid:10543146 |
| Capone D et al. | Effects of itraconazole on tacrolimus blood concentrations in a renal transplant recipient. | 1999 | Ann Pharmacother | pmid:10534229 |
| MistrÃková J et al. | Increased neoplasm development due to immunosuppressive treatment with FK-506 in BALB/C mice persistently infected with the mouse herpesvirus (MHV-72). | 1999 | Viral Immunol. | pmid:10532652 |
| Leroy-Matheron C et al. | Inhibitor against coagulation factor V after liver transplantation. | 1999 | Transplantation | pmid:10532550 |
| Migita K et al. | FK506 markedly enhances apoptosis of antigen-stimulated peripheral T cells by down-regulation of Bcl-xL. | 1999 | Transplantation | pmid:10532544 |
| Ellis D et al. | Epstein-Barr virus-related disorders in children undergoing renal transplantation with tacrolimus-based immunosuppression. | 1999 | Transplantation | pmid:10532541 |
| Morris-Stiff G et al. | Immunosuppression in renal transplantation. Meta-analysis should not have included one of the studies. | 1999 | BMJ | pmid:10531121 |
| Minematsu T et al. | Sustained QT prolongation induced by tacrolimus in guinea pigs. | 1999 | Life Sci. | pmid:10530807 |
| Okada M et al. | Successful treatment of chronic graft-versus-host disease with sulfasalazine in allogeneic bone marrow transplantation. | 1999 | Acta Haematol. | pmid:10529517 |
| Morita H et al. | Immunosuppressive effect of leukotriene B(4) receptor antagonist in vitro. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10529362 |
| Cannon RD et al. | Clinical efficacy of the Abbott Tacrolimus II assay for the IMx. | 1999 Oct-Dec | Ann. Clin. Lab. Sci. | pmid:10528829 |
| Grimbert P et al. | Tacrolimus (FK506)-induced severe and late encephalopathy in a renal transplant recipient. | 1999 | Nephrol. Dial. Transplant. | pmid:10528682 |
| Shadidy M et al. | Biochemical analysis of mouse FKBP60, a novel member of the FKPB family. | 1999 | Biochim. Biophys. Acta | pmid:10524204 |
| Lee SF et al. | Cytokine receptor common beta chain as a potential activator of cytokine withdrawal-induced apoptosis. | 1999 | Mol. Cell. Biol. | pmid:10523628 |
| Mao Z and Wiedmann M | Calcineurin enhances MEF2 DNA binding activity in calcium-dependent survival of cerebellar granule neurons. | 1999 | J. Biol. Chem. | pmid:10521511 |
| Hübner GI et al. | Drug interaction between mycophenolate mofetil and tacrolimus detectable within therapeutic mycophenolic acid monitoring in renal transplant patients. | 1999 | Ther Drug Monit | pmid:10519451 |
| Yoshimoto T and Siesjö BK | Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia. | 1999 | Brain Res. | pmid:10519051 |
| Pacocha SE et al. | Regulation of antigen-induced human T-lymphocyte responses by calcineurin antagonists. | 1999 | J. Allergy Clin. Immunol. | pmid:10518828 |
| Bekersky I et al. | Bioequivalence of 1 and 5 mg tacrolimus capsules using a replicate study design. | 1999 | J Clin Pharmacol | pmid:10516937 |
| Przepiorka D et al. | Tacrolimus and minidose methotrexate for prevention of acute graft-versus-host disease after HLA-mismatched marrow or blood stem cell transplantation. | 1999 | Bone Marrow Transplant. | pmid:10516680 |
| Moore JM | NMR techniques for characterization of ligand binding: utility for lead generation and optimization in drug discovery. | 1999 | Biopolymers | pmid:10516573 |
| Cardenas ME et al. | Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action. | 1999 | Clin. Microbiol. Rev. | pmid:10515904 |
| Cunningham EB | An inositolphosphate-binding immunophilin, IPBP12. | 1999 | Blood | pmid:10515881 |
| Fan L et al. | Improved artificial death switches based on caspases and FADD. | 1999 | Hum. Gene Ther. | pmid:10515447 |
| Charney DA et al. | Plasma cell-rich acute renal allograft rejection. | 1999 | Transplantation | pmid:10515379 |
| Rostaing L et al. | Differences in Type 1 and Type 2 intracytoplasmic cytokines, detected by flow cytometry, according to immunosuppression (cyclosporine A vs. tacrolimus) in stable renal allograft recipients. | 1999 | Clin Transplant | pmid:10515221 |
| Robinson BV et al. | Optimal dosing of intravenous tacrolimus following pediatric heart transplantation. | 1999 | J. Heart Lung Transplant. | pmid:10512526 |
| Dusting GJ et al. | Cyclosporin A and tacrolimus (FK506) suppress expression of inducible nitric oxide synthase in vitro by different mechanisms. | 1999 | Br. J. Pharmacol. | pmid:10510443 |
| Böttiger Y et al. | Tacrolimus whole blood concentrations correlate closely to side-effects in renal transplant recipients. | 1999 | Br J Clin Pharmacol | pmid:10510159 |
| Lee WP and Mathes DW | Hand transplantation: pertinent data and future outlook. | 1999 | J Hand Surg Am | pmid:10509267 |
| Sche PP et al. | Display cloning: functional identification of natural product receptors using cDNA-phage display. | 1999 | Chem. Biol. | pmid:10508685 |
| Chautan M et al. | Interdigital cell death can occur through a necrotic and caspase-independent pathway. | 1999 | Curr. Biol. | pmid:10508592 |
| Tredger JM et al. | Performance of the IMx tacrolimus II assay and practical limits of detection. | 1999 | Clin. Chem. | pmid:10508145 |
| Cao Z et al. | Comparison of tacrolimus concentrations measured by the IMx tacrolimus II vs the PRO-TRAC II FK506 ELISA assays. | 1999 | Clin. Chem. | pmid:10508139 |
| Cacciarelli TV et al. | An analysis of pretransplantation variables associated with long-term allograft outcome in pediatric liver transplant recipients receiving primary tacrolimus (FK506) therapy. | 1999 | Transplantation | pmid:10507484 |
| Letko E et al. | Tacrolimus (FK 506). | 1999 | Ann. Allergy Asthma Immunol. | pmid:10507260 |
| Linder MW and Elin RJ | Implications of methodologic bias for therapeutic drug monitoring. | 1999 | Arch. Pathol. Lab. Med. | pmid:10506447 |
| Yoshimura R et al. | The effect of immunosuppressive agents (FK-506, rapamycin) on renal P450 systems in rat models. | 1999 | J. Pharm. Pharmacol. | pmid:10504034 |