tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Immunoblastic Lymphadenopathy D007119 2 associated lipids
Ileal Neoplasms D007078 2 associated lipids
Hypothermia D007035 19 associated lipids
Hypotension D007022 41 associated lipids
Hypoglycemia D007003 13 associated lipids
Hypertension, Renal D006977 9 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypertension D006973 115 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypersensitivity D006967 22 associated lipids
Hyperparathyroidism, Secondary D006962 4 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperkalemia D006947 3 associated lipids
Hyperglycemia D006943 21 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hypercalcemia D006934 13 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Hyperalgesia D006930 42 associated lipids
Hydronephrosis D006869 4 associated lipids
Deltaretrovirus Infections D006800 1 associated lipids
HIV Seropositivity D006679 15 associated lipids
Herpesviridae Infections D006566 4 associated lipids
Herpes Labialis D006560 1 associated lipids
Hernia, Ventral D006555 1 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hepatolenticular Degeneration D006527 3 associated lipids
Hepatitis C D006526 7 associated lipids
Hepatitis, Viral, Animal D006524 4 associated lipids
Hepatic Veno-Occlusive Disease D006504 1 associated lipids
Budd-Chiari Syndrome D006502 1 associated lipids
Hemorrhage D006470 15 associated lipids
Hemophilia A D006467 10 associated lipids
Hemolytic-Uremic Syndrome D006463 2 associated lipids
Hemolysis D006461 131 associated lipids
Hematuria D006417 13 associated lipids
Hematoma D006406 5 associated lipids
Hematologic Diseases D006402 3 associated lipids
Heart Injuries D006335 6 associated lipids
Heart Failure D006333 36 associated lipids
Cardiomegaly D006332 31 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Hearing Loss, Noise-Induced D006317 4 associated lipids
Hearing Loss, Bilateral D006312 1 associated lipids
Headache D006261 4 associated lipids
Hand Injuries D006230 1 associated lipids
Hand Dermatoses D006229 5 associated lipids
Hallucinations D006212 4 associated lipids
Gynecomastia D006177 6 associated lipids
Graves Disease D006111 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Ong CS Tacrolimus ointment for atopic dermatitis. 1998 N. Engl. J. Med. pmid:9867560
Sharma AK and Holder FE Clostridium difficile diarrhea after use of tacrolimus following renal transplantation. 1998 Clin. Infect. Dis. pmid:9868682
Pascual M et al. Plasma exchange and tacrolimus-mycophenolate rescue for acute humoral rejection in kidney transplantation. 1998 Transplantation pmid:9869086
Kawai M et al. Studies on an immunosuppressive macrolactam, ascomycin: synthesis of a C-33 hydroxyl derivative. 1998 Bioorg. Med. Chem. Lett. pmid:9871515
Schultz LW and Clardy J Chemical inducers of dimerization: the atomic structure of FKBP12-FK1012A-FKBP12. 1998 Bioorg. Med. Chem. Lett. pmid:9871618
Mohri T et al. Rapid adhesion and spread of non-adherent colon cancer Colo201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A. 1998 Cell Struct. Funct. pmid:9872566
Goulet MT et al. C32-O-imidazol-2-yl-methyl ether derivatives of the immunosuppressant ascomycin with improved therapeutic potential. 1998 Bioorg. Med. Chem. Lett. pmid:9873523
Takamatsu H et al. Neuroprotective effects depend on the model of focal ischemia following middle cerebral artery occlusion. 1998 Eur. J. Pharmacol. pmid:9874163
Murthy JN et al. Tacrolimus metabolite cross-reactivity in different tacrolimus assays. 1998 Clin. Biochem. pmid:9876892
Naruse K et al. Uni-axial cyclic stretch induces c-src activation and translocation in human endothelial cells via SA channel activation. 1998 FEBS Lett. pmid:9877176