Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Alloway RR | Mounting Clinical Evidence With Tacrolimus Generic Products. | 2017 | Transplantation | pmid:28749820 |
Wei L et al. | Therapeutic Effects of FK506 on IgA Nephropathy Rat. | 2017 | Kidney Blood Press. Res. | pmid:29179182 |
Lee D et al. | Age and Early Graft Function Relate With Risk-Benefit Ratio of Allogenic Islet Transplantation Under Antithymocyte Globulin-Mycophenolate Mofetil-Tacrolimus Immune Suppression. | 2017 | Transplantation | pmid:27779572 |
Li X et al. | Tacrolimus induces fibroblasts apoptosis and reduces epidural fibrosis by regulating miR-429 and its target of RhoE. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28669722 |
Chen YS et al. | Population pharmacokinetic analysis of tacrolimus in Chinese myasthenia gravis patients. | 2017 | Acta Pharmacol. Sin. | pmid:28552913 |
Kim HS et al. | The Protective Effect of Febuxostat on Chronic Tacrolimus-Induced Nephrotoxicity in Rats. | 2017 | Nephron | pmid:27701176 |
Berntsen HF et al. | The fungal neurotoxin penitrem A induces the production of reactive oxygen species in human neutrophils at submicromolar concentrations. | 2017 | Toxicology | pmid:29037868 |
Eleftheriadis T et al. | In human cell cultures, everolimus is inferior to tacrolimus in inhibiting cellular alloimmunity, but equally effective as regards humoral alloimmunity. | 2017 | Int Urol Nephrol | pmid:28508247 |
Banovic F et al. | Therapeutic effectiveness of calcineurin inhibitors in canine vesicular cutaneous lupus erythematosus. | 2017 | Vet. Dermatol. | pmid:28439997 |
Huang TQ et al. | Protection of FK506 against neuronal apoptosis and axonal injury following experimental diffuse axonal injury. | 2017 | Mol Med Rep | pmid:28339015 |
Truffinet O et al. | Tacrolimus Exerts Only a Transient Effectiveness in Refractory Pediatric Crohn Disease: A Case Series. | 2017 | J. Pediatr. Gastroenterol. Nutr. | pmid:27429426 |
Vanhove T et al. | Determinants of the Magnitude of Interaction Between Tacrolimus and Voriconazole/Posaconazole in Solid Organ Recipients. | 2017 | Am. J. Transplant. | pmid:28224698 |
Spallanzani V et al. | Red blood cell exchange as an approach for treating a case of severe tacrolimus overexposure. | 2017 | Transfus. Apher. Sci. | pmid:28223040 |
Kirpalani A et al. | Idiosyncratic drug reactions and membranous glomerulopathy. | 2017 | BMJ Case Rep | pmid:28137906 |
Kim JM et al. | Differences in Peripheral Blood Lymphocytes between Brand-Name and Generic Tacrolimus Used in Stable Liver Transplant Recipients. | 2017 | Med Princ Pract | pmid:28092916 |
Srivastava AK et al. | Serial in vivo imaging of transplanted allogeneic neural stem cell survival in a mouse model of amyotrophic lateral sclerosis. | 2017 | Exp. Neurol. | pmid:28038988 |
Yang D et al. | JC polyomavirus nephropathy, a rare cause of transplant dysfunction: Case report and review of literature. | 2017 | Transpl Infect Dis | pmid:28036142 |
Van Laecke S et al. | Effect of Magnesium Supplements on Insulin Secretion After Kidney Transplantation: A Randomized Controlled Trial. | 2017 | Ann. Transplant. | pmid:28848225 |
Triñanes J et al. | Deciphering Tacrolimus-Induced Toxicity in Pancreatic β Cells. | 2017 | Am. J. Transplant. | pmid:28432716 |
Al-Kadhimi Z et al. | Low incidence of severe cGvHD and late NRM in a phase II trial of thymoglobulin, tacrolimus and sirolimus for GvHD prevention. | 2017 | Bone Marrow Transplant. | pmid:28581472 |