| MeSH term | MeSH ID | Detail |
|---|---|---|
| Infection | D007239 | 6 associated lipids |
| Abnormalities, Multiple | D000015 | 13 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Bone Diseases | D001847 | 4 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
| Ulcer | D014456 | 16 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Obesity | D009765 | 29 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
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|---|---|---|---|---|
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| Elmer DS et al. | Metabolic effects of FK 506 (tacrolimus) versus cyclosporine in portally drained pancreas allografts. | 1998 | Transplant. Proc. | pmid:9532159 |
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| Wakizaka Y et al. | Xenotransplantation of hamster liver into Gunn rats reserves congenital hyperbilirubinemia. | 1996 | Transplant. Proc. | pmid:8623372 |
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| Serrano M et al. | Clinical value of a single determination of intracellular ATP levels in stimulated CD4+ T lymphocytes in pediatric patients with stable liver transplantation. | 2012 | Transplant. Proc. | pmid:23146475 |
| Charco R et al. | Hypercholesterolemia in long-term survivors of liver transplantation: a comparison between cyclosporine and FK 506. | 1998 | Transplant. Proc. | pmid:9636605 |
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| DÃaz-Molina B et al. | Effect of CYP3A5, CYP3A4, and ABCB1 genotypes as determinants of tacrolimus dose and clinical outcomes after heart transplantation. | 2012 | Transplant. Proc. | pmid:23146479 |
| San Segundo D et al. | Study of B-cell subpopulations in lung transplant recipients with posttransplant infection. | 2012 | Transplant. Proc. | pmid:23146491 |
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| Tanabe K et al. | Excellent outcome of ABO-incompatible living kidney transplantation under pretransplantation immunosuppression with tacrolimus, mycophenolate mofetil, and steroid. | 2004 | Transplant. Proc. | pmid:15518791 |
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| Morris RE et al. | A study of the contrasting effects of cyclosporine, FK 506, and rapamycin on the suppression of allograft rejection. | 1990 | Transplant. Proc. | pmid:1697111 |
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| Sano N et al. | Oral FK 506 blood levels are elevated in pig short bowel model: further investigations with co-administration of an intestinal CYP3A4 inhibitor. | 2002 | Transplant. Proc. | pmid:12034301 |
| Charco R et al. | Changes in renal function in long-term survivors of liver transplantation: a comparison between cyclosporine microemulsion and tacrolimus therapy. | 2002 | Transplant. Proc. | pmid:12176478 |
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| Yokoyama I et al. | Immunosuppressant effect on Fas antigen expression and p53 of an experimental tumor. | 1998 | Transplant. Proc. | pmid:9865346 |
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| Gerauer K et al. | Long-term cardiac allograft survival in mice treated with malononitrilamide 715. | 1998 | Transplant. Proc. | pmid:9865349 |
| Prasad GV et al. | Role of dietary salt intake in posttransplant hypertension with tacrolimus-based immunosuppression. | 2005 | Transplant. Proc. | pmid:15919496 |
| Miller J et al. | FK 506 in kidney transplantation: results of the U.S.A. randomized comparative phase III study. The FK 506 Kidney Transplant Study Group. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123008 |
| Jordan ML et al. | Five-year experience with tacrolimus rescue for renal allograft rejection. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123009 |
| Toyama Y et al. | Prolonged small bowel graft survival using photochemotherapy and low-dose FK 506. | 1996 | Transplant. Proc. | pmid:8907924 |
| Yamada T et al. | Synergistic effect of FK 506 and trifluoperazine on the immunosuppression in rat small bowel transplantation. | 1996 | Transplant. Proc. | pmid:8907927 |
| Malaise J et al. | Tacrolimus compared with cyclosporine microemulsion in primary simultaneous pancreas-kidney transplantation: the EURO-SPK 3-year results. | 2005 Jul-Aug | Transplant. Proc. | pmid:16182828 |
| Zmonarski SC et al. | Lowering of Messenger Ribonucleic Acid Toll-Like Receptors 2-4,9 in Peripheral Blood Mononuclear Cells in Kidney Allograft Recipients, Relationships With Immunosuppressive Treatment, and Delayed Graft Function Occurrence. | 2016 | Transplant. Proc. | pmid:27496439 |
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| Crespo-Leiro MG | Tacrolimus in heart transplantation. | 2003 | Transplant. Proc. | pmid:12962869 |
| Perico N et al. | FK 506 does not affect the glomerular filtration rate and renal plasma flow in the rat. | 1991 | Transplant. Proc. | pmid:1721378 |
| Zegarska J et al. | Evaluation of the Relationship Between Concentrations of Tacrolimus Metabolites, 13-O-Demethyl Tacrolimus and 15-O-Demethyl Tacrolimus, and Clinical and Biochemical Parameters in Kidney Transplant Recipients. | 2018 | Transplant. Proc. | pmid:30177142 |
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