tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Rheumatoid Nodule D012218 1 associated lipids
Hernia, Ventral D006555 1 associated lipids
Hepatitis, Autoimmune D019693 1 associated lipids
Moyamoya Disease D009072 1 associated lipids
Polyomavirus Infections D027601 1 associated lipids
Lymphohistiocytosis, Hemophagocytic D051359 1 associated lipids
Multiple Endocrine Neoplasia Type 2a D018813 1 associated lipids
Apraxias D001072 1 associated lipids
Hypertensive Encephalopathy D020343 1 associated lipids
Hearing Loss, Bilateral D006312 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Gerber DA et al. Immunosuppressive agents: recent developments in molecular action and clinical application. 1998 Transplant. Proc. pmid:9636637
Schneeberger H et al. Tacrolimus as a primary immunosuppressive therapy in cadaveric renal transplantation: five years' experience at a single center. 1998 Transplant. Proc. pmid:9636642
Resch K and Szamel M Molecular mechanisms of the immunosuppressive action of cyclosporin A. 1997 Sep-Oct Int. J. Immunopharmacol. pmid:9637358
Baldari CT et al. NF-AT-luciferase reporter T cell lines as tools to screen immunosuppressive drugs. 1998 Biologicals pmid:9637743
Abraham RT Mammalian target of rapamycin: immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling. 1998 Curr. Opin. Immunol. pmid:9638370
Takahara S et al. A comparative study of FK506 granules and capsules in renal transplant recipients. 1998 Transpl. Int. pmid:9638846
Morris-Stiff G and Jurewicz WA Single centre experience with mycophenolate mofetil for refractory rejection in cadaveric renal transplantation. 1998 Transpl. Int. pmid:9638849
Murray M et al. Comparison of tacrolimus absorption in transplant patients receiving continuous versus interrupted enteral nutritional feeding. 1998 Ann Pharmacother pmid:9640479
Kuwata T et al. A role of calcineurin in coreceptor regulation during differentiation of Cd4+Cd8+ T cells. 1998 Biochem. Biophys. Res. Commun. pmid:9642110
Gruessner RW et al. Suggested guidelines for the use of tacrolimus in pancreas/kidney transplantation. 1998 Clin Transplant pmid:9642520
Gabe SM et al. The effect of tacrolimus (FK506) on intestinal barrier function and cellular energy production in humans. 1998 Gastroenterology pmid:9649460
Canzanello VJ et al. Late hypertension after liver transplantation: a comparison of cyclosporine and tacrolimus (FK 506). 1998 Liver Transpl Surg pmid:9649648
Friberg H et al. Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. 1998 J. Neurosci. pmid:9651198
Tarumi K et al. The plasma FK506-binding protein 12 level is related to acute cellular rejection in small bowel transplantation. 1998 Immunopharmacol Immunotoxicol pmid:9653668
Kommers T et al. Regulation of the phosphorylation of glial fibrillary acidic protein (GFAP) by glutamate and calcium ions in slices of immature rat spinal cord: comparison with immature hippocampus. 1998 Neurosci. Lett. pmid:9654363
Cetinkale O et al. Involvement of neutrophils in ischemia-reperfusion injury of inguinal island skin flaps in rats. 1998 Plast. Reconstr. Surg. pmid:9655420
Matsui H et al. [Physiological role of calcineurin in central nervous system]. 1998 Tanpakushitsu Kakusan Koso pmid:9655961
Tamura K [Multiple actions of tacrolimus and cyclosporin A as specific inhibitors of calcineurin]. 1998 Tanpakushitsu Kakusan Koso pmid:9655970
Morozumi K et al. [Current topics of the rejection pathology in human renal allografts]. 1998 Hinyokika Kiyo pmid:9656109
Nishioka T et al. [Is tacrolimus effective for ongoing renal allograft rejection?]. 1998 Hinyokika Kiyo pmid:9656112