tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Cardiomyopathy, Restrictive D002313 1 associated lipids
Paraparesis, Tropical Spastic D015493 1 associated lipids
Neurodermatitis D009450 1 associated lipids
Posterior Leukoencephalopathy Syndrome D054038 1 associated lipids
Ecthyma, Contagious D004474 1 associated lipids
Priapism D011317 1 associated lipids
Vulvar Lichen Sclerosus D007724 1 associated lipids
Myelinolysis, Central Pontine D017590 1 associated lipids
Protoporphyria, Erythropoietic D046351 1 associated lipids
Smooth Muscle Tumor D018235 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Kato K et al. Modulation of long-term potentiation induction in the hippocampus by N-methyl-D-aspartate-mediated presynaptic inhibition. 1999 Neuroscience pmid:10426482
Pirenne J Contribution of large animal models to the development of clinical intestinal transplantation. 1999 Apr-Jun Acta Gastroenterol. Belg. pmid:10427786
Jamieson NV Adult small intestinal transplantation in Europe. 1999 Apr-Jun Acta Gastroenterol. Belg. pmid:10427790
Kahan BD An immunosuppressive triumvirate to minimize renal injuries associated with calcineurin antagonist therapy. 1999 Transplantation pmid:10428260
Reichenspurner H et al. Optimization of the immunosuppressive protocol after lung transplantation. 1999 Transplantation pmid:10428269
Soccal PM et al. Improvement of drug-induced chronic renal failure in lung transplantation. 1999 Transplantation pmid:10428288
Levy GA Neoral/cyclosporine-based immunosuppression. 1999 Liver Transpl Surg pmid:10431016
Pollock R and Rivera VM Regulation of gene expression with synthetic dimerizers. 1999 Meth. Enzymol. pmid:10432459
Shinkura N et al. Autoantibodies to FK506 binding protein 12 (FKBP12) in autoimmune diseases. 1999 Autoimmunity pmid:10433096
Briggs WA et al. Lymphocyte suppression by rolipram with other immunosuppressive drugs. 1999 J Clin Pharmacol pmid:10434230
Harikrishnan P and Harden PN Tacrolimus can resolve cyclosporin-induced gingival hyperplasia. 1999 Nephrol. Dial. Transplant. pmid:10435907
Tsuji Y et al. Effects of cyclosporin A, FK506 and steroid hormones on hair growth. 1999 Exp. Dermatol. pmid:10439282
Sheikh AM et al. Concomitant human immunodeficiency virus protease inhibitor therapy markedly reduces tacrolimus metabolism and increases blood levels. 1999 Transplantation pmid:10440408
Moxey-Mims MM Increased incidence of insulin-dependent diabetes mellitus in pediatric renal transplant patients receiving tacrolimus (FK506) 1999 Transplantation pmid:10440413
Magee CC et al. Nocardial infection in a renal transplant recipient on tacrolimus and mycophenolate mofetil. 1999 Clin. Nephrol. pmid:10442495
Kur F et al. Tacrolimus (FK506) as primary immunosuppressant after lung transplantation. 1999 Thorac Cardiovasc Surg pmid:10443520
Uchiyama H et al. Approach to withdrawal from tacrolimus in a fully allogeneic murine skin graft model. 1999 Immunology pmid:10447745
Volbracht C et al. ATP controls neuronal apoptosis triggered by microtubule breakdown or potassium deprivation. 1999 Mol. Med. pmid:10449809
Goulet MT et al. C32-O-phenalkyl ether derivatives of the immunosuppressant ascomycin: a tether length study. 1999 Bioorg. Med. Chem. Lett. pmid:10450986
Armstrong HM et al. Potent immunosuppressive C32-O-arylethyl ether derivatives of ascomycin with reduced toxicity. 1999 Bioorg. Med. Chem. Lett. pmid:10450987