tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Esophageal Perforation D004939 1 associated lipids
Epididymitis D004823 1 associated lipids
Pruritus Vulvae D011539 1 associated lipids
Central Serous Chorioretinopathy D056833 1 associated lipids
Feline Acquired Immunodeficiency Syndrome D016181 1 associated lipids
Budd-Chiari Syndrome D006502 1 associated lipids
AIDS-Associated Nephropathy D016263 1 associated lipids
Oral Ulcer D019226 1 associated lipids
Epidermolysis Bullosa Dystrophica D016108 1 associated lipids
Primary Graft Dysfunction D055031 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
St A Nunes FA and Lucey MR Searching for a balance when applying immunosuppression after liver transplantation. 2001 Transplantation pmid:11258425
Ringe B et al. A novel management strategy of steroid-free immunosuppression after liver transplantation: efficacy and safety of tacrolimus and mycophenolate mofetil. 2001 Transplantation pmid:11258429
Matsuda S et al. Two distinct action mechanisms of immunophilin-ligand complexes for the blockade of T-cell activation. 2000 EMBO Rep. pmid:11258483
Queille-Roussel C et al. The new topical ascomycin derivative SDZ ASM 981 does not induce skin atrophy when applied to normal skin for 4 weeks: a randomized, double-blind controlled study. 2001 Br. J. Dermatol. pmid:11260007
Weir MR et al. Long-term impact of discontinued or reduced calcineurin inhibitor in patients with chronic allograft nephropathy. 2001 Kidney Int. pmid:11260422
Chand DH et al. Tacrolimus: the good, the bad, and the ugly. 2001 Pediatr Transplant pmid:11260486
Grotz WH et al. Calcineurin-inhibitor induced pain syndrome (CIPS): a severe disabling complication after organ transplantation. 2001 Transpl. Int. pmid:11263551
Nikiforow S et al. CD4+ T-cell effectors inhibit Epstein-Barr virus-induced B-cell proliferation. 2001 J. Virol. pmid:11264363
Vasquez E et al. Clotrimazole increases tacrolimus blood levels: a drug interaction in kidney transplant patients. 2001 Clin Transplant pmid:11264634
Nagashima N et al. Decreased effect of immunosuppression on immunocompetence in African--Americans after kidney and liver transplantation. 2001 Clin Transplant pmid:11264637
Ciancio G et al. The use of intravenous tacrolimus and mycophenolate mofetil as induction and maintenance immunosuppression in simultaneous pancreas--kidney recipients with previous transplants. 2001 Clin Transplant pmid:11264642
Utsugi R et al. Tolerance across a two-haplotype, fully MHC-mismatched barrier induced in miniature swine renal allografts treated with a 12-day course of tacrolimus. 2001 Feb-Mar Transplant. Proc. pmid:11266727
Gasser M et al. Putative regulatory function of alloreactive Th2 cells in tolerant recipients after small bowel transplantation. 2001 Feb-Mar Transplant. Proc. pmid:11266759
Nakao A et al. Changes of allo-intestinal graft survival and intragraft cytokine expression by bone marrow augmentation with tacrolimus treatment in rats. 2001 Feb-Mar Transplant. Proc. pmid:11266851
Janezic AL et al. Alternatively spliced variants of IL-2 mRNA in sequential transplant kidney core needle biopsies. 2001 Feb-Mar Transplant. Proc. pmid:11266873
Opelz G New immunosuppressants and HLA matching. 2001 Feb-Mar Transplant. Proc. pmid:11266911
Jiang H et al. IL-10: a tacrolimus-specific cytotoxic mediator in ongoing allograft rejection. 2001 Feb-Mar Transplant. Proc. pmid:11266931
Orsenigo R et al. FK506 and SMS 201-995: effect on heterotopic heart transplantation in rats. 2001 Feb-Mar Transplant. Proc. pmid:11266956
Ishibashi M et al. Experimental study of tacrolimus immunosuppression on the mode of administration: efficacy of constant intravenous infusion avoiding C(max). 2001 Feb-Mar Transplant. Proc. pmid:11266958
Erickson LM et al. Gene expression profiles of rat heart allografts with immunosuppression. 2001 Feb-Mar Transplant. Proc. pmid:11266960
Reutzel-Selke A et al. Donor pretreatment of grafts from marginal donors improves long-term graft outcome. 2001 Feb-Mar Transplant. Proc. pmid:11267150
Ettenger R The practical problems of prednisone in pediatric renal transplantation. 2001 Feb-Mar Transplant. Proc. pmid:11267159
Berloco P et al. Tacrolimus as cornerstone immunosuppressant in kidney transplantation. 2001 Feb-Mar Transplant. Proc. pmid:11267161
Ciancio G et al. Daclizumab induction for primary kidney transplant recipients using tacrolimus, mycophenolate mofetil, and steroids as maintenance immunosuppression. 2001 Feb-Mar Transplant. Proc. pmid:11267169
Vincenti F Tacrolimus (FK 506) in kidney transplantation: five-year survival results of the U.S. multicenter, randomized, comparative trial. 2001 Feb-Mar Transplant. Proc. pmid:11267172
Calconi G and Vianello A One-year follow-up of a large European trial comparing dual versus triple tacrolimus-based immunosuppressive regimens following renal transplantation. 2001 Feb-Mar Transplant. Proc. pmid:11267173
Pretagostini R et al. Conversion from cyclosporin to tacrolimus in chronic allograft nephropathy. 2001 Feb-Mar Transplant. Proc. pmid:11267174
Abouljoud M et al. Conversion to neoral provides effective rescue therapy for liver and kidney transplant patients intolerant of Prograf. 2001 Feb-Mar Transplant. Proc. pmid:11267175
Kauffman HM et al. Drug regimens affect cadaveric kidney graft survival. 2001 Feb-Mar Transplant. Proc. pmid:11267176
Dudley CR Conversion at first rejection: a prospective trial comparing cyclosporine microemulsion with tacrolimus in renal transplant recipients. 2001 Feb-Mar Transplant. Proc. pmid:11267179
Wang W et al. Effect of rapamycin and FK506 on mesangial cell proliferation. 2001 Feb-Mar Transplant. Proc. pmid:11267180
Salazar A et al. Sirolimus-tacrolimus combination for combined kidney-pancreas transplantation: effect on renal function. 2001 Feb-Mar Transplant. Proc. pmid:11267181
Zaltzman J et al. Tacrolimus, MMF, steroid, and ALG immunotherapy for high immunological risk renal transplant recipients. 2001 Feb-Mar Transplant. Proc. pmid:11267183
Zamauskaite A et al. FK506 and CsA differ in their effect on intracellular cytokine expression following kidney transplantation. 2001 Feb-Mar Transplant. Proc. pmid:11267184
Aguirrezabalaga J et al. Lipid profiles in liver transplantation in patients receiving tacrolimus or cyclosporin. 2001 Feb-Mar Transplant. Proc. pmid:11267192
Shishido S et al. Pharmacokinetics of tacrolimus in pediatric renal transplant recipients. 2001 Feb-Mar Transplant. Proc. pmid:11267193
Glanemann M et al. Mycophenolate mofetil is superior in combination with tacrolimus compared to cyclosporine for immunosuppressive therapy after liver transplantation. 2001 Feb-Mar Transplant. Proc. pmid:11267194
van den Berg AP et al. Prediction of the inhibition of IL-2 production by calcineurin inhibitors. 2001 Feb-Mar Transplant. Proc. pmid:11267197
Wu M et al. Cyclosporine and tacrolimus alter renin-angiotesin system in mouse medullary-thick ascending limb cultured cells. 2001 Feb-Mar Transplant. Proc. pmid:11267198
Luke PP et al. IVIG rescue therapy in renal transplantation. 2001 Feb-Mar Transplant. Proc. pmid:11267206
Felipe CR et al. Choosing the right dose of new immunossuppressive drugs for new populations: importance of pharmacokinetic studies. 2001 Feb-Mar Transplant. Proc. pmid:11267207
Evans NJ et al. The expression of endothelin and inducible nitric oxide synthase in human renal allografts and their role in chronic renal allograft nephropathy. 2001 Feb-Mar Transplant. Proc. pmid:11267247
Cailhier JF et al. CMV in kidney transplants in the tacrolimus-mycophenolate era. 2001 Feb-Mar Transplant. Proc. pmid:11267255
Quiroga I et al. Differential homocysteine levels in renal transplant patients receiving neoral versus tacrolimus. 2001 Feb-Mar Transplant. Proc. pmid:11267261
Chakrabarti P et al. Outcome after steroid withdrawal in adult renal transplant patients receiving tacrolimus-based immunosuppression. 2001 Feb-Mar Transplant. Proc. pmid:11267274
Del Castillo D Analysis of primary and recurrent rejection following renal transplantation in a large, comparative, multicentre trial. 2001 Feb-Mar Transplant. Proc. pmid:11267283
Busque S et al. Canadian multicentre trial of tacrolimus/azathioprine/steroids versus tacrolimus/mycophenolate mofetil/steroids versus neoral/mycophenolate mofetil/steroids in renal transplantation. 2001 Feb-Mar Transplant. Proc. pmid:11267285
Sperschneider H A large, multicentre trial to compare the efficacy and safety of tacrolimus with cyclosporine microemulsion following renal transplantation. 2001 Feb-Mar Transplant. Proc. pmid:11267291
Mühlbacher F Tacrolimus versus cyclosporin microemulsion in liver transplantation: results of a 3-month study. 2001 Feb-Mar Transplant. Proc. pmid:11267317
Peltekian K et al. De novo use of low-dose tacrolimus and sirolimus in liver transplantation. 2001 Feb-Mar Transplant. Proc. pmid:11267318