| MeSH term | MeSH ID | Detail |
|---|---|---|
| Granuloma Annulare | D016460 | 1 associated lipids |
| Paraneoplastic Syndromes, Nervous System | D020361 | 1 associated lipids |
| Intestinal Fistula | D007412 | 1 associated lipids |
| Latent Tuberculosis | D055985 | 1 associated lipids |
| Nephritis, Hereditary | D009394 | 1 associated lipids |
| Mastocytosis, Cutaneous | D034701 | 1 associated lipids |
| Pancreatitis, Graft | D055589 | 1 associated lipids |
| Hearing Loss, Sudden | D003639 | 1 associated lipids |
| Rectal Diseases | D012002 | 1 associated lipids |
| Citrullinemia | D020159 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Saito K et al. | Severe diffuse duodenitis successfully treated with intravenous tacrolimus after colectomy for ulcerative colitis. | 2014 | Intern. Med. | pmid:25366006 |
| Labrador J et al. | Risk factors for thrombotic microangiopathy in allogeneic hematopoietic stem cell recipients receiving GVHD prophylaxis with tacrolimus plus MTX or sirolimus. | 2014 | Bone Marrow Transplant. | pmid:24566710 |
| Liu Y et al. | Role of retrograde trafficking in stress response, host cell interactions, and virulence of Candida albicans. | 2014 | Eukaryotic Cell | pmid:24363364 |
| Wei TQ et al. | Sandwich assay for tacrolimus using 2 antitacrolimus antibodies. | 2014 | Clin. Chem. | pmid:24381229 |
| Kurzawski M et al. | CYP3A5 and CYP3A4, but not ABCB1 polymorphisms affect tacrolimus dose-adjusted trough concentrations in kidney transplant recipients. | 2014 | Pharmacogenomics | pmid:24444408 |
| Xue F et al. | CYP3A5 genotypes affect tacrolimus pharmacokinetics and infectious complications in Chinese pediatric liver transplant patients. | 2014 | Pediatr Transplant | pmid:24438215 |
| Chen YK et al. | Personalized tacrolimus dose requirement by CYP3A5 but not ABCB1 or ACE genotyping in both recipient and donor after pediatric liver transplantation. | 2014 | PLoS ONE | pmid:25310192 |
| Steinebrunner N et al. | Pharmacodynamic monitoring of nuclear factor of activated T cell-regulated gene expression in liver allograft recipients on immunosuppressive therapy with calcineurin inhibitors in the course of time and correlation with acute rejection episodes--a prospective study. | 2014 | Ann. Transplant. | pmid:24457606 |
| Müller GG et al. | Topical tacrolimus 0.03% as sole therapy in vernal keratoconjunctivitis: a randomized double-masked study. | 2014 | Eye Contact Lens | pmid:24418865 |
| Hesselink DA et al. | The role of pharmacogenetics in the disposition of and response to tacrolimus in solid organ transplantation. | 2014 | Clin Pharmacokinet | pmid:24249597 |
| Zhu X et al. | Pilot study using tacrolimus rather than cyclosporine plus antithymocyte globulin as an immunosuppressive therapy regimen option for severe aplastic anemia in adults. | 2014 | Blood Cells Mol. Dis. | pmid:24931461 |
| Doligalski CT et al. | Sublingual administration of tacrolimus: current trends and available evidence. | 2014 | Pharmacotherapy | pmid:25251980 |
| Souza MC et al. | Tacrolimus-loaded PLGA implants: in vivo release and ocular toxicity. | 2014 | Curr. Eye Res. | pmid:24325382 |
| Talreja N et al. | Successful desensitization to agalsidase beta after anaphylaxis. | 2014 | Ann. Allergy Asthma Immunol. | pmid:24331397 |
| Ricciardelli I et al. | Towards gene therapy for EBV-associated posttransplant lymphoma with genetically modified EBV-specific cytotoxic T cells. | 2014 | Blood | pmid:25185261 |
| Mujtaba MA et al. | Conversion from tacrolimus to belatacept to prevent the progression of chronic kidney disease in pancreas transplantation: case report of two patients. | 2014 | Am. J. Transplant. | pmid:25179306 |
| Huang H et al. | Effect and mechanism of tacrolimus on melanogenesis on A375 human melanoma cells. | 2014 | Chin. Med. J. | pmid:25131236 |
| Choi SW et al. | Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation: a phase 1/2 trial. | 2014 | Lancet Oncol. | pmid:24295572 |
| Zwiech R | [The early C4d urinary excretion and long-term kidney graft survival in patients treated with tacrolimus and mycophenolate mophetil]. | 2014 | Pol. Merkur. Lekarski | pmid:24779215 |
| Boschetti G et al. | Tacrolimus induction followed by maintenance monotherapy is useful in selected patients with moderate-to-severe ulcerative colitis refractory to prior treatment. | 2014 | Dig Liver Dis | pmid:25023007 |
| Personett HA et al. | Impact of molecular adsorbent recirculating system therapy on tacrolimus elimination: a case report. | 2014 | Transplant. Proc. | pmid:25017243 |
| Enderby CY et al. | Tacrolimus dosage requirements in lung transplant recipients receiving antifungal prophylaxis with voriconazole followed by itraconazole: a preliminary prospective study. | 2014 | Clin Transplant | pmid:24931421 |
| Feng S et al. | A rapidly reversible chemical dimerizer system to study lipid signaling in living cells. | 2014 | Angew. Chem. Int. Ed. Engl. | pmid:24841150 |
| Rotter D et al. | Calcineurin and its regulator, RCAN1, confer time-of-day changes in susceptibility of the heart to ischemia/reperfusion. | 2014 | J. Mol. Cell. Cardiol. | pmid:24838101 |
| Fazal MA et al. | Dyslipidaemia among renal transplant recipients: cyclosporine versus tacrolimus. | 2014 | J Pak Med Assoc | pmid:25272531 |
| Muduma G et al. | A UK analysis of the cost of switching renal transplant patients from an immediate-release to a prolonged-release formulation of tacrolimus based on differences in trough concentration variability. | 2014 | J Med Econ | pmid:24754700 |
| Bloch J et al. | Donor ABCB1 genetic polymorphisms influence epithelial-to-mesenchyme transition in tacrolimus-treated kidney recipients. | 2014 | Pharmacogenomics | pmid:25521359 |
| Hodzic E et al. | Posterior reversible encephalopathy syndrome (PRES) as a complication of immunosuppressive therapy in renal transplantation in children. | 2014 | Med Arh | pmid:25195358 |
| Chen Y et al. | Comparison of long-term impact of immunosuppressants at therapeutic doses on hepatic function and histological changes in unilateral nephrectomized rats. | 2014 | Exp. Toxicol. Pathol. | pmid:25081300 |
| Xie M et al. | Brucellosis infection in an adult liver transplant recipient. | 2014 | Transpl Infect Dis | pmid:24666385 |
| Takazono T et al. | Paradoxical response to disseminated non-tuberculosis mycobacteriosis treatment in a patient receiving tumor necrosis factor-α inhibitor: a case report. | 2014 | BMC Infect. Dis. | pmid:24576098 |
| Heilman RL et al. | Delayed allograft inflammation following alemtuzumab induction for kidney transplantation. | 2013 Sep-Oct | Clin Transplant | pmid:23924146 |
| Benoit S and Hamm H | Psoriasis from a prosthesis: unusual Koebner phenomenon in a girl with autoamputation of the leg. | 2013 Sep-Oct | Pediatr Dermatol | pmid:23360396 |
| Zahdi MR et al. | Erosive pustular dermatosis of the scalp successfully treated with oral prednisone and topical tacrolimus. | 2013 Sep-Oct | An Bras Dermatol | pmid:24173187 |
| Riva N et al. | [Pharmacovigilance of calcineurin inhibitor in peidatric kidney and liver transplantation]. | 2013 Nov-Dec | Farm Hosp | pmid:24256007 |
| Brodrick B et al. | Influence of treatments on prognosis for vulvar lichen sclerosus: facts and controversies. | 2013 Nov-Dec | Clin. Dermatol. | pmid:24160287 |
| Bloom RD et al. | A randomized, crossover pharmacokinetic study comparing generic tacrolimus vs. the reference formulation in subpopulations of kidney transplant patients. | 2013 Nov-Dec | Clin Transplant | pmid:24118450 |
| Labirua-Iturburu A et al. | Calcineurin inhibitors in a cohort of patients with antisynthetase-associated interstitial lung disease. | 2013 May-Jun | Clin. Exp. Rheumatol. | pmid:23465087 |
| Chen SY et al. | Individualization of tacrolimus dosage basing on cytochrome P450 3A5 polymorphism--a prospective, randomized, controlled study. | 2013 May-Jun | Clin Transplant | pmid:23432535 |
| Ramirez CB et al. | Completely steroid-free immunosuppression in liver transplantation: a randomized study. | 2013 May-Jun | Clin Transplant | pmid:23621629 |
| Krishna N et al. | Tacrolimus-induced paranoid delusions and fugue-like state. | 2013 May-Jun | Gen Hosp Psychiatry | pmid:22959421 |
| He L et al. | Treatment of idiopathic membranous nephropathy with combination of low-dose tacrolimus and corticosteroids. | 2013 May-Jun | J. Nephrol. | pmid:22956434 |
| Kanzelmeyer NK et al. | Correlations with six-month protocol biopsy findings in pediatric transplant recipients on low- and regular-dose CNI regimens. | 2013 Mar-Apr | Clin Transplant | pmid:23414365 |
| Tiwari R et al. | Enhancements in healthcare information technology systems: customizing vendor-supplied clinical decision support for a high-risk patient population. | 2013 Mar-Apr | J Am Med Inform Assoc | pmid:22813760 |
| Albekairy A et al. | Cytochrome P450 3A4FNx011B as pharmacogenomic predictor of tacrolimus pharmacokinetics and clinical outcome in the liver transplant recipients. | 2013 Mar-Apr | Saudi J Gastroenterol | pmid:23481136 |
| LaMattina JC et al. | Native kidney function following liver transplantation using calcineurin inhibitors: single-center analysis with 20 years of follow-up. | 2013 Mar-Apr | Clin Transplant | pmid:23294013 |
| Alfson ED et al. | Lysis of catatonic withdrawal by propofol in a bone-marrow transplant recipient with adenovirus limbic encephalitis. | 2013 Mar-Apr | Psychosomatics | pmid:22705183 |
| Yoshida EM et al. | Canadian national retrospective chart review comparing the long term effect of cyclosporine vs. tacrolimus on clinical outcomes in patients with post-liver transplantation hepatitis C virus infection. | 2013 Mar-Apr | Ann Hepatol | pmid:23396740 |
| Castillo G et al. | [Acute cellular rejection in a liver transplantation patient due to changing the brand of a generic immunosuppressant]. | 2013 Jul-Sep | Rev Gastroenterol Mex | pmid:23866966 |
| Bechstein WO et al. | A comparative, randomized trial of concentration-controlled sirolimus combined with reduced-dose tacrolimus or standard-dose tacrolimus in renal allograft recipients. | 2013 Jul-Aug | Transplant. Proc. | pmid:23953523 |
| Zhao YJ et al. | Late, severe, noninfectious diarrhea after renal transplantation: high-risk factors, therapy, and prognosis. | 2013 Jul-Aug | Transplant. Proc. | pmid:23953533 |
| Weiler N et al. | Tacrolimus effects and side effects after liver transplantation: is there a difference between immediate and extended release? | 2013 Jul-Aug | Transplant. Proc. | pmid:23953543 |
| Stringa P et al. | Ischemic preconditioning and tacrolimus pretreatment as strategies to attenuate intestinal ischemia-reperfusion injury in mice. | 2013 Jul-Aug | Transplant. Proc. | pmid:23953566 |
| Tachibana A et al. | Repopulation of the immunosuppressed retrorsine-treated infant rat liver with human hepatocytes. | 2013 Jul-Aug | Xenotransplantation | pmid:23683097 |
| Favi E et al. | Tacrolimus plus mycophenolate mofetil vs. cyclosporine plus everolimus in deceased donor kidney transplant recipients: three-yr results of a single-center prospective clinical trial. | 2013 Jul-Aug | Clin Transplant | pmid:23710603 |
| Eberlin M et al. | Increased medication compliance of liver transplant patients switched from a twice-daily to a once-daily tacrolimus-based immunosuppressive regimen. | 2013 Jul-Aug | Transplant. Proc. | pmid:23726723 |
| Satyanarayan HS et al. | Efficacy and tolerability of combined treatment with NB-UVB and topical tacrolimus versus NB-UVB alone in patients with vitiligo vulgaris: a randomized intra-individual open comparative trial. | 2013 Jul-Aug | Indian J Dermatol Venereol Leprol | pmid:23760325 |
| Babalola O and Strober BE | Treatment of atopic dermatitis in pregnancy. | 2013 Jul-Aug | Dermatol Ther | pmid:23914886 |
| Conti R et al. | Jessner-Kanof disease: two effective and sure therapeutic options. | 2013 Jul-Aug | Dermatol Ther | pmid:23914897 |
| Chakkera HA et al. | Genetic differences in Native Americans and tacrolimus dosing after kidney transplantation. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375287 |
| Tian Ch et al. | B- and T-lymphocyte attenuator/herpes virus entry mediator as early indicators for acute rejection following kidney transplantation. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375291 |
| Yao B et al. | The incidence of posttransplantation diabetes mellitus during follow-up in kidney transplant recipients and relationship to Fok1 vitamin D receptor polymorphism. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375298 |
| Miyazaki T et al. | Two case reports of successful withdrawal of mycofenolate mofetil after living donor lobar lung transplantation. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375323 |
| Chang HY et al. | Long-term follow-up of arrhythmia characteristics and clinical outcomes in heart transplant patients. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375324 |
| Al Nahdi N et al. | First successful treatment of post-liver transplant hepatitis C fibrosing cholestatic hepatitis with boceprevir, peginterferon and ribavirin in a pre-transplant null responder. | 2013 Jan-Feb | Ann Hepatol | pmid:23293209 |
| Seco-Melantuche R et al. | [Incidence of drug-induced thrombocytopenia in hospitalized patients]. | 2013 Jan-Feb | Farm Hosp | pmid:23461497 |
| Rao V et al. | A non-induction renal sparing approach after liver transplantation: high dose mycophenolate mofetil with delayed, low-dose tacrolimus. | 2013 Jan-Feb | Transplant. Proc. | pmid:23267806 |
| Langone A et al. | Does reduction in mycophenolic acid dose compromise efficacy regardless of tacrolimus exposure level? An analysis of prospective data from the Mycophenolic Renal Transplant (MORE) Registry. | 2013 Jan-Feb | Clin Transplant | pmid:22861144 |
| Shiba H et al. | Switching from tacrolimus to cyclosporine A to prevent primary biliary cirrhosis recurrence after living-donor liver transplantation. | 2013 Apr-Jun | Int Surg | pmid:23701152 |
| Adamu B et al. | New-onset diabetes after renal transplantation: a case series as seen in a Nigerian kidney transplant population. | 2013 Apr-Jun | Niger J Clin Pract | pmid:23563475 |
| Cangemi G et al. | Comparison of antibody-conjugated magnetic immunoassay and liquid chromatography-tandem mass spectrometry for the measurement of cyclosporine and tacrolimus in whole blood. | 2013 Apr-Jun | Int J Immunopathol Pharmacol | pmid:23755756 |
| Nakatani K | [Personalized medicine in transplantation therapy]. | 2013 | Rinsho Byori | pmid:23947183 |
| Vassal O et al. | [Bacterial parotitis in an immunocompromised patient in adult ICU]. | 2013 | Ann Fr Anesth Reanim | pmid:23948025 |
| Rabie R et al. | Efficacy of antiviral therapy for hepatitis C after liver transplantation with cyclosporine and tacrolimus: a systematic review and meta-analysis. | 2013 | Liver Transpl. | pmid:22821730 |
| Nonaka K et al. | Intractable membranous lupus nephritis showing selective improvement of subepithelial deposits with tacrolimus therapy: a case report. | 2013 | Clin. Nephrol. | pmid:22541676 |
| Boivin AA et al. | Influence of SLCO1B3 genetic variations on tacrolimus pharmacokinetics in renal transplant recipients. | 2013 | Drug Metab. Pharmacokinet. | pmid:23149872 |
| van den Hoogen MW et al. | Effect of a single intraoperative high-dose ATG-Fresenius on delayed graft function in donation after cardiac-death donor renal allograft recipients: a randomized study. | 2013 | Exp Clin Transplant | pmid:23431996 |
| Brown RS et al. | Topical tacrolimus with custom trays in the treatment of severe oral chronic graft-versus-host disease refractory to a potent topical steroid therapy: a case report. | 2013 | Oral Surg Oral Med Oral Pathol Oral Radiol | pmid:23102802 |
| van den Hoogen MW et al. | Insulin requirement after a renal transplant in patients with type 2 diabetes: the choice of calcineurin inhibitors. | 2013 | Exp Clin Transplant | pmid:23432070 |
| Du J et al. | Long-term efficacy and safety of tacrolimus ointment in the treatment of vitiligo. | 2013 | J. Dermatol. | pmid:24111918 |
| Uchino M et al. | Topical tacrolimus therapy for antibiotic-refractory pouchitis. | 2013 | Dis. Colon Rectum | pmid:24022534 |
| de Jonge H et al. | Impact of CYP3A5 genotype on tacrolimus versus midazolam clearance in renal transplant recipients: new insights in CYP3A5-mediated drug metabolism. | 2013 | Pharmacogenomics | pmid:24024898 |
| Shihab FS et al. | Effect of corticosteroid withdrawal on tacrolimus and mycophenolate mofetil exposure in a randomized multicenter study. | 2013 | Am. J. Transplant. | pmid:23167508 |
| Rojas LE et al. | Meta-analysis and systematic review of the effect of the donor and recipient CYP3A5 6986A>G genotype on tacrolimus dose requirements in liver transplantation. | 2013 | Pharmacogenet. Genomics | pmid:23873120 |
| Jones AC et al. | Phage p1-derived artificial chromosomes facilitate heterologous expression of the FK506 gene cluster. | 2013 | PLoS ONE | pmid:23874942 |
| Tadano T et al. | [A case of calcineurin-inhibitor induced pain syndrome associated with tacrolimus therapy for ulcerative colitis]. | 2013 | Nihon Shokakibyo Gakkai Zasshi | pmid:24097149 |
| Faralli JA et al. | Dexamethasone increases αvβ3 integrin expression and affinity through a calcineurin/NFAT pathway. | 2013 | Biochim. Biophys. Acta | pmid:24100160 |
| Valente G et al. | Conversion from twice-daily to once-daily tacrolimus in stable liver transplant patients: effectiveness in a real-world setting. | 2013 | Transplant. Proc. | pmid:23622676 |
| Landy J et al. | Oral tacrolimus as maintenance therapy for refractory ulcerative colitis--an analysis of outcomes in two London tertiary centres. | 2013 | J Crohns Colitis | pmid:23623737 |
| Karapetyan YE et al. | Unique drug screening approach for prion diseases identifies tacrolimus and astemizole as antiprion agents. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23576755 |
| Israni AK et al. | Tacrolimus trough levels after month 3 as a predictor of acute rejection following kidney transplantation: a lesson learned from DeKAF Genomics. | 2013 | Transpl. Int. | pmid:23879408 |
| Huang D et al. | Genome-scale metabolic network guided engineering of Streptomyces tsukubaensis for FK506 production improvement. | 2013 | Microb. Cell Fact. | pmid:23705993 |
| Ban YH et al. | Characterization of FK506 biosynthetic intermediates involved in post-PKS elaboration. | 2013 | J. Nat. Prod. | pmid:23706030 |
| Pamuk F et al. | Effects of tacrolimus and nifedipine, alone or in combination, on gingival tissues. | 2013 | J. Periodontol. | pmid:23289868 |
| Zlatic SA et al. | Chemical-genetic disruption of clathrin function spares adaptor complex 3-dependent endosome vesicle biogenesis. | 2013 | Mol. Biol. Cell | pmid:23761069 |
| Ceschi A et al. | Acute calcineurin inhibitor overdose: analysis of cases reported to a national poison center between 1995 and 2011. | 2013 | Am. J. Transplant. | pmid:23279718 |
| López E et al. | FKBP52 is involved in the regulation of SOCE channels in the human platelets and MEG 01 cells. | 2013 | Biochim. Biophys. Acta | pmid:23228564 |
| Fujita Y et al. | Analysis of cytochrome P450 gene polymorphism in a lupus nephritis patient in whom tacrolimus blood concentration was markedly elevated after administration of azole antifungal agents. | 2013 | J Clin Pharm Ther | pmid:22971159 |
| Sofue T et al. | Excess fluid distribution affects tacrolimus absorption in peritoneal dialysis patients. | 2013 | Clin. Exp. Nephrol. | pmid:23269423 |
| Loar RW et al. | Posterior reversible encephalopathy syndrome and hemorrhage associated with tacrolimus in a pediatric heart transplantation recipient. | 2013 | Pediatr Transplant | pmid:23331314 |